Comparative Quality Assessment of Three Different Marketed Brands of Indian Polyherbal Formulation - Triphala Churna

Agarwal, Princy

doi:10.26717/bjstr.2018.05.001237

Cited by 4 publications

(15 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Presence of ascorbic acid may contribute to the low pH of the Triphala formulations. Previous study done with different brands of Triphala churna in India also showed comparable pH values 3 while a study reported different pH value. 34 Loss on drying was used to determine the volatile constituents in powdered drugs.…”

Section: Discussionmentioning

confidence: 73%

“…In the previous study on Triphala churna, the phytochemical screening of the aqueous extract of different brands revealed the presence of carbohydrates, steroids, flavonoids, tannins, saponins, phenols and ascorbic acid while glycosides only in one brand with the absence of alkaloids, proteins, amino acids and terpenoids. 3 However, another study done for a marketed brand and a lab-prepared sample confirmed the presence of alkaloids and the absence of saponins and proteins. 30 Another study confirmed the absence of glycosides, proteins, saponins, alkaloids and phytosterols.…”

Section: Discussionmentioning

confidence: 94%

“…Preliminary phytochemical screening of aqueous extracts of each brand of Triphala powder was performed to detect various bioactive substances such as alkaloids, carbohydrates, reducing sugar, flavonoids, saponins, tannins, steroids, proteins, amino acids, glycosides, phenols, terpenoids and ascorbic acid. 3,24…”

Section: Preliminary Phytochemical Screeningmentioning

confidence: 99%

“…Physicochemical tests such as determination of pH value, 3 moisture content (Loss on Drying), Loss on Ignition, 28 ash values (Total ash, Acidinsoluble ash, Water-soluble ash) and extractive values (Ethanol-soluble and Water-soluble extractive value) were done in triplicate for each brands.…”

Section: Physicochemical Analysismentioning

confidence: 99%

“…The World Health Organization has been estimated that 80% of the population in developing countries depends on traditional herbal medicines. The herbal products are widely used as a complementary and alternative medicine for different ailments, [1][2][3] and also people use those as dietary supplements 4,5 in Sri Lanka. Triphala is a poly-herbal medicine, which consists of dried fruits of three medicinal plants which are Terminalia chebula Retz (Family Combretaceae), Terminalia bellerica Roxb (Family Combretaceae) and Phyllanthus emblica L. (Family Phyllanthaceae) in equal proportions, based on Ayurvedic Formulary of India (AFI).…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Comparative Quality Evaluation of Different Brands of ‘Triphala’: A Polyherbal Medicine in Sri Lanka

Premathilake¹,

Thuvaragan²,

Sanmugarajah³

et al. 2021

JYP

View full text Add to dashboard Cite

Background: Triphala is a well-known polyherbal formulation widely used as an herbal, complementary and alternative medicine for various ailments, especially for gastrointestinal problems, and it is used as a dietary supplement for long years. Objectives: Objective of this study was to comparatively evaluate the quality of three marketed brands of Triphala tablets (Brand T 1 and T 2 ) and capsules (Brand T 3 ) which are available in Sri Lanka. Materials and Methods: This laboratory based experimental qualitative study was done among three brands of Triphala. Phytochemical screening was carried out for all those brands. Physicochemical tests were also performed to determine pH, moisture content, and loss on ignition, ash values and extractive values. Data were analysed by using Statistical Package of Social Sciences 23. Results: Physicochemical tests revealed that all three brands failed to comply with pharmacopoeial limits at least in one physicochemical test. According to ANOVA test, there was significant difference between results of physicochemical tests of marketed brands of Triphala. Conclusion: All three Triphala brands did not meet the quality standards. Quality of herbal medicine marketed in Sri Lanka should be monitored and regularized by relevant authorities.

show abstract

Section: Discussionmentioning

confidence: 73%

Section: Discussionmentioning

confidence: 94%

Section: Preliminary Phytochemical Screeningmentioning

confidence: 99%

Section: Physicochemical Analysismentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Comparative Quality Evaluation of Different Brands of ‘Triphala’: A Polyherbal Medicine in Sri Lanka

Premathilake¹,

Thuvaragan²,

Sanmugarajah³

et al. 2021

JYP

View full text Add to dashboard Cite

show abstract

Pharmaceutical and Pharmacological Evaluation of Amoxicillin after Solubility Enhancement Using the Spray Drying Technique

et al. 2022

View full text Add to dashboard Cite

The dose frequency of drugs belonging to class II is usually high and associated with harmful effects on the body. The study aimed to enhance the solubility of the poorly water-soluble drug amoxicillin (AM) by the solid dispersion (SD) technique. Six different SDs of AM, F1−F6, were prepared by the spray drying technique using two other carriers, HP-β-CD (F1−F3) and HPMC (F4−F6), in 1:1, 1:2, and 1:3 drug-to-polymer ratios. These SDs were analyzed to determine their practical yield, drug content, and aqueous solubility using analytical techniques such as Fourier transform infrared spectroscopy, scanning electron microscopy, thermogravimetric analysis, and powder X-ray diffraction. The effect of polymer concentration on SDs was determined using aqueous solubility, in vitro dissolution, and in vivo studies. The results showed no drug−polymer interactions in SDs. Solubility studies showed that SDs based on the drug-to-polymer ratio of 1:2 (F2 and F5) were highly soluble in water compared to those with ratios of 1:1 and 1:3. In vitro dissolution studies also showed that SDs with a ratio of 1:2 released the highest drug concentration from both polymeric systems. The SDs based on HPMC confirmed the more sustained release of the drug as compared to that of HP-β-CD. All the SDs were observed as stable and amorphous, with a smooth spherical surface. In vivo studies reveal the enhancement of pharmacokinetics parameters as compared to standard AM. Hence, it is confirmed that spray drying is an excellent technique to enhance the solubility of AM in an aqueous medium. This may contribute to the enhancement of the pharmacokinetic behaviors of SDs.

show abstract

Effect of Particle Size on Physical Properties of Rambutan Seed Powder

So’bah Ahmad,

Rabiatul ‘Adawiyah Sayuti

2024

JRNN

View full text Add to dashboard Cite

Rambutan seed powder is derived from the crushing of dried seed of rambutan (Nephelium lappaceum L.) and it is promisingly used as an incorporating powder into food product. However, there is limited information on the effects of particle size on the handling and processing of rambutan seed powder in the industry. Therefore, a study was performed to determine the effects of particle sizes on physical properties of rambutan seeds powder. The physical properties measured moisture content, bulk and tapped density, as well as flowability characteristics. In this work, the powders were classified based on their mean diameter (d50) that ranged between less than 250 μm, between 250 μm and 750 μm and more than 750 μm. The fine rambutan seed powder (RSP) with particle 250 μm to 750 μm exhibited the best powder characteristics as it holds lowest moisture content, 5.42% and fair and passable flow properties, with Hausner ratio of 1.26 ± 1.20. The results indicated a significant impact of particle size on the cohesivity, where smaller particle size tended to decrease flowability and caused caking and agglomeration, which led to undesirable quality of food product.

show abstract

Comparative Quality Assessment of Three Different Marketed Brands of Indian Polyherbal Formulation - Triphala Churna

Cited by 4 publications

References 1 publication

Comparative Quality Evaluation of Different Brands of ‘Triphala’: A Polyherbal Medicine in Sri Lanka

Comparative Quality Evaluation of Different Brands of ‘Triphala’: A Polyherbal Medicine in Sri Lanka

Pharmaceutical and Pharmacological Evaluation of Amoxicillin after Solubility Enhancement Using the Spray Drying Technique

Effect of Particle Size on Physical Properties of Rambutan Seed Powder

Contact Info

Product

Resources

About