1965
DOI: 10.1111/j.1749-6632.1965.tb49390.x
|View full text |Cite
|
Sign up to set email alerts
|

Comparative Morphology of the Cardiac Conduction Tissue in Animals*

Abstract: The gross distribution, histologic structure, blood supply, innervation, and physiologic implications of this unique fiber system has continued to attract the research interests of investigators from many disciplines of science. The resulting body of diverse information is a voluminous and indeed a fascinating scientific story.A complete survey of even the essential achievements is beyond the limited time and scope of this presentation. However, the interested reader can obtain an appreciation of advancements … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

1
20
0
2

Year Published

1971
1971
2012
2012

Publication Types

Select...
9

Relationship

0
9

Authors

Journals

citations
Cited by 105 publications
(23 citation statements)
references
References 22 publications
1
20
0
2
Order By: Relevance
“…(6) Previous histological and immonohistochemical studies by James,(10;13;24) Truex et al,(11;25) and Schuessler et al(5;26) support our functional and structural data, which demonstrate that the canine and human SAN are electrically insulated from most of the nearby atrial myocardium except for several SEPs. This conduction barrier is formed by the sinus nodal coronary arteries, connective tissue, and fat, as well as an abrupt change in Cx43 expression between atrial and nodal cells.…”
Section: Discussionsupporting
confidence: 83%
“…(6) Previous histological and immonohistochemical studies by James,(10;13;24) Truex et al,(11;25) and Schuessler et al(5;26) support our functional and structural data, which demonstrate that the canine and human SAN are electrically insulated from most of the nearby atrial myocardium except for several SEPs. This conduction barrier is formed by the sinus nodal coronary arteries, connective tissue, and fat, as well as an abrupt change in Cx43 expression between atrial and nodal cells.…”
Section: Discussionsupporting
confidence: 83%
“…Anatomical (10,27,29,49,50) and functional (7,46) studies suggest that the canine SAN (23) is a more realistic model for the human SAN (21) than that of small mammals (9,22). Figure 1 represents a more recent view of the structure of SAN pacemaker complex in canine and human hearts that consists of several major pacemaker compartments (head, center, and tail) surrounded by coronary arteries, fibrous tissue, fat, and the atrial myocardium all situated along CT.…”
Section: New Model Of the Canine And Human San Pacemaker Complexmentioning
confidence: 96%
“…Moreover, with the exception of mitochondrial density which depends on heart size, all cardiac myocytes have the same size and morphology, making it difficult to distinguish the myocytes of one species from another [16–19]. The same is true for specialised cardiac tissue such as the His bundles responsible for the conduction of the electrical impulse from the atria to the ventricles [20, 21]. …”
Section: Morphological Similarity Of the Mammalian Heartmentioning
confidence: 99%