Comparative metabolite fingerprinting of chia, flax and sesame seeds using LC-MS untargeted metabolomics

Brigante, Federico I.; Podio, Natalia S.; Wunderlin, Daniel Alberto; Baroni, María Verónica

doi:10.1016/j.foodchem.2021.131355

Cited by 16 publications

(4 citation statements)

References 32 publications

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“…Nevertheless, the FPJ group separated from the MC group, and the metabolic profiles of samples in the FPJ and MC groups were in two different dimensions of the PC2 axis. In addition, the QC group was well clustered near the origin of the PCA score, indicating that the sample preparation method had good repeatability and stable data quality (Brigante et al, 2022). As shown in Figure 3E, R 2 Y evaluated the goodness of fit of the model that represented the fraction of explained Y‐variation, whereas Q 2 estimated the prediction ability (Niu et al, 2018).…”

Section: Resultsmentioning

confidence: 99%

Serum metabonomic study to explore the amelioration mechanisms of co‐fermented collagen peptide‐jackfruit juice on the immunosuppressed mice

Ma,

Cheng,

Wen

et al. 2024

eFood

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The main purpose of this study was to investigate the improvement effect and serum metabolomic analysis of co‐fermented collagen peptide‐jackfruit juice (FPJ) against immunosuppression in cyclophosphamide‐induced mice. Serum samples were analyzed using ultra‐performance liquid chromatography coupled with mass spectrometry (UPLC‐MS/MS) targeted metabolomics technology, including the normal group, model group, and FPJ group, and determine if such treatments were able to revert immunosuppression‐related metabolic changes to normal status. The results showed that 32 differential metabolites were upregulated and 42 metabolites were downregulated in the model group compared with the normal group. After FPJ intervention, there was a trend of normal callback. Adenosine, inosine, guanosine, 2‐deoxyadenosine, hypoxanthine, xanthine, d‐xylulose‐5‐phosphate, ribulose‐5‐phosphate, phenylpyruvic acid, hippuric acid, 3‐(3‐hydroxyphenyl)‐propionic acid, 3‐ureidopropionate, uridine, dCDP and malonic acid may be used as predictive markers of immunosuppression. Notably, these biomarkers were involved in purine metabolism, pentose phosphate pathway, phenylalanine metabolism, and pyrimidine metabolism. In this study, FPJ inhibited oxidative stress and improved the gut microbes by regulating the disorders of metabolic pathways. The metabolomics approach developed herein provides novel insight into the metabolic disturbances associated with immunosuppression, which will contribute to understanding the mechanism of FPJ on immunosuppression further and providing a basis for further research.

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Section: Resultsmentioning

confidence: 99%

Serum metabonomic study to explore the amelioration mechanisms of co‐fermented collagen peptide‐jackfruit juice on the immunosuppressed mice

Ma,

Cheng,

Wen

et al. 2024

eFood

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“…The main problems in the storage of flax seed, especially if it is related to food products for health [1] consumer properties [2] is to ensure product quality. In particular, the article [3] describes special methods for determining flax seed quality indicators, including those related to damage, but the latter problem is not sufficiently developed.…”

Section: Problem Descriptionmentioning

confidence: 99%

Innovative technologies for the processing of raw materials of plant origin to improve the quality of food supply of the troops

Riabchykov

Tsykhanovska

Tovma

et al. 2022

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The object of research: morphological and cultural characteristics of micromycetes: yeast Saccharomyces cerevisiae and mycelial fungi Mucorracemosus grown on agar medium.The subject of research: flax seed suspension, ultrafine powder of double oxide of divalent and trivalent ferrum, micromycetes: yeast Saccharomyces cerevisiae and mycelial fungi MucorracemosusInvestigated problem: ensuring the bacteriostatic properties of raw materials and obtaining products with an extended dates of expiry.The subject in scientific results: the impact of nanoparticles (NP FeO×Fe2O3) on the bacteriostatic (protective) properties of flax seeds against fungal infections has been studied and the dependence of bacteriostatic properties on the amount of nanomagnetite has been determined. The ability of nanomagnetite to improve the bacteriostatic properties of flax seeds has been proven: addition of 0.1 %; 0.15 %; 0.2 % of nanomagnetite suppresses the development of microflora (micromycetes) in flax seed samples by 8–20 times. A reduction in the number of micromycetes (yeast Saccharomycescerevisiae and mycelial fungi Mucorracemosus) by 8–10 times and the size by 10–20 times was established compared to the control. The rational content of nanoparticles (NPs FeO×Fe2O3–nanomagnetite) has been determined as 0.15 % of the weight of the recipe mixture. The proposed mathematical model makes it possible to predict the effectiveness of using NP FeO×Fe2O3 – nanomagnetite to inhibit the growth of mycelial fungi to ensure the bacteriostatic properties of raw materials, in particular, flax seeds. The area of practical use of the research results: food industry enterprises specializing in the production of bakery and flour confectionery products using a mixture of wheat and rye flour with the addition of food additives. Innovative technological product: flour raw material with a mineral nano-additive suspension based on the double oxide of divalent and trivalent ferrum, which allows to ensure quality and extend dates of expiry of the product. Scope of the innovative technological product: to enhance the quality of food supply of the troops in extreme conditions

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“…It is feasible to evaluate raw materials through qualitative and quantitative analyses of known specific functional components. As a result, a fingerprint‐based evaluation system has been widely used for evaluating the quality of PNPs, such as traditional Chinese medicine and food seasoning 7,8 . However, there are still many challenges to be faced in new resource functional, active ingredient discovery, quality marker screening, and functional comparison, establishing a rapid, comprehensive, and effective method.…”

Section: Introductionmentioning

confidence: 99%

Screening strategy for predominant phenolic components of digestive enzyme inhibitors in passion fruit peel extracts on simulated gastrointestinal digestion

et al. 2022

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BACKGROUND The targeted biological activity of a natural product is often the result of the combined action of multiple functional components. Screening for predominant contributing components of targeting activity is crucial for quality evaluation. RESULTS Thirteen and nine phenolic compounds inhibiting α‐glucosidase and α‐amylase, respectively, were identified in the ethanol extracts of passion fruit peel through liquid chromatography–tandem mass spectrometry and multivariate analysis. Considering the different concentrations of components and their interactions, the role of the semi‐inhibitory concentration (IC50) in the dose–effect relationship is limited. We proposed the active contribution rate (ACR), which is the ratio of a single component concentration to its IC50 in the whole, to assess the relative activity of each compound. Luteolin, quercetin, and vitexin exhibited a minimum IC50. Before the simulation of gastrointestinal digestion, quercetin, salicylic acid, and luteolin were identified as the dominant contributors to α‐glucosidase inhibition according to ACR, while salicylic acid, 2,3‐dihydroxybenzoic acid, and quercetin were identified as dominant contributors to α‐amylase inhibition. After simulated digestion, the contents of all polyphenolic compounds decreased by various degrees. Salicylic acid, gentisic acid, and vitexin became the dominant inhibitors of α‐glucosidase based on ACR (cumulative 57.96%), while salicylic acid and 2,3‐dihydroxybenzoic acid became the dominant inhibitors of α‐amylase (cumulative 84.50%). CONCLUSION Therefore, the ACR evaluation strategy can provide a quantitative reference for screening the predominant contributor components of a specific activity in complex systems. © 2022 Society of Chemical Industry.

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Comparative metabolite fingerprinting of chia, flax and sesame seeds using LC-MS untargeted metabolomics

Cited by 16 publications

References 32 publications

Serum metabonomic study to explore the amelioration mechanisms of co‐fermented collagen peptide‐jackfruit juice on the immunosuppressed mice

Serum metabonomic study to explore the amelioration mechanisms of co‐fermented collagen peptide‐jackfruit juice on the immunosuppressed mice

Innovative technologies for the processing of raw materials of plant origin to improve the quality of food supply of the troops

Screening strategy for predominant phenolic components of digestive enzyme inhibitors in passion fruit peel extracts on simulated gastrointestinal digestion

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