Comparative In Vitro Activities of Amoxicillin-Clavulanate against Aerobic and Anaerobic Bacteria Isolated from Antral Puncture Specimens from Patients with Sinusitis

Goldstein, Ellie J. C.; Citron, Diane M.; Merriam, C. Vreni

doi:10.1128/aac.43.3.705

Cited by 18 publications

(10 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Prevotella species, anaerobic streptococci, and Fusobacterium species accounted for 75% of anaerobic pathogens isolated in the present study, a finding consistent with results of other studies [2][3][4][7][8][9][10]. Goldstein et al [15] reported selected antimicrobial susceptibilities of a large number of aerobic ( ) and anaerobic ( ) pathogens ison p 207 n p 162 lated from antral sinus puncture specimens (type not stated) during 1994-1999. They noted a diversity of aerobic and anaerobic bacteria, a finding similar to that of our study.…”

Section: Discussionsupporting

confidence: 93%

Bacteriologic Findings Associated with Chronic Bacterial Maxillary Sinusitis in Adults

et al. 2002

View full text Add to dashboard Cite

An open-label, multicenter study was performed to assess bacteriologic findings associated with chronic bacterial maxillary sinusitis in adults. Seventy aerobic (52.2%) and 64 anaerobic (47.8%) pathogens were recovered from clinically evaluable patients at baseline (before therapy). The most commonly isolated anaerobes were Prevotella species (31.1%), anaerobic streptococci (21.9%), and Fusobacterium species (15.6%). The aerobes most frequently recovered included Streptococcus species (21.4%), Haemophilus influenzae (15.7%), Pseudomonas aeruginosa (15.7%), and Staphylococcus aureus and Moraxella catarrhalis (10.0% each). Recurrences of signs or symptoms of bacterial maxillary sinusitis associated with anaerobes were twice as frequent as were those associated with aerobes when counts of anaerobes were > or =10(3) cfu/mL. A pathogenic role for Granulicatella species in cases of chronic sinusitis was documented for the first time.

show abstract

Section: Discussionsupporting

confidence: 93%

Bacteriologic Findings Associated with Chronic Bacterial Maxillary Sinusitis in Adults

et al. 2002

View full text Add to dashboard Cite

show abstract

“…The use of postoperative topical antibiotics for up to two weeks is recommended to minimize the risk of infection, but their usefulness has never been formally demonstrated 41,48,49. Moreover, the long treatment period and the excessive use of antibiotics play a role in the development of resistant bacterial strains 44,50…”

Section: Current Use Of Topical Antibacterial Eye Dropsmentioning

confidence: 99%

A European Perspective on Topical Ophthalmic Antibiotics: Current and Evolving Options

2011

View full text Add to dashboard Cite

BackgroundEye infections can be vision-threatening and must be treated effectively by appropriate and safe use of topical ophthalmic anti-infectives. This review will essentially consider the current and evolving treatment options for the various types of bacterial eye infections. Ocular surface bacterial infections affect subjects of all ages with a high frequency in newborns and children.MethodsThis article presents a review of the peer-reviewed published scientific literature in order to define the well-established uses of anti-infective eye drops in the field of ocular infections. A comprehensive search of the recent published literature including topical ophthalmic anti-infectives effective in bacterial ocular infections was performed. Clinical studies provide relevant data concerning the characteristics and clinical efficacy of antibacterial eye drops in ocular anterior segment infections or for perioperative prophylaxis. Publications were included to cover the current options of antibacterial eye drops available in Europe.ResultsSeveral recent publications identified effective topical ocular antibacterials requiring a reduced dose regimen and a short treatment course. Additional literature reviewed included data on novel perioperative prophylaxis, indications for topical fortified antibiotics and innovative research including the risk of resistance.ConclusionsSafe and effective topical antibiotic eye drops for the treatment and prevention of ocular infections must be adapted to the type of bacteria suspected. Usual topical antimicrobials should be replaced by more recent and more effective treatments. The use of highly effective fluoroquinolones should be reserved for the most severe cases to avoid resistance. Short treatment courses, such as azithromycin, can be easily used in children, thereby improving quality of life.

show abstract

“…Goldstein et al. likewise found significantly greater susceptibility of antral bacterial strains to amoxicillin/clavulanate than to amoxicillin in adult sinusitis patients . Furthermore, amoxicillin/clavulanate was active against all isolated strains and exhibited the greatest activity against the spectrum of aerobic and anaerobic specimens examined …”

Section: Discussionmentioning

confidence: 96%

“…Given the absence of direct evidence for antibiotic prophylaxis before SES, inclusion criteria were expanded to incorporate papers of all levels of evidence, including expert opinion. Publications providing indirect evidence for appropriate prophylactic antibiotic regimens (e.g., studies testing antibiotic sensitivity in sinusitis patients) were also included ( Table ) . Studies that merely reported use of perioperative antibiotics for SES or associated postsurgical complications were excluded, as these reports neither provided rationale for antibiotic selection nor sought to specifically justify use of one antibiotic over another .…”

Section: Search Outcomementioning

confidence: 99%

“…Publications providing indirect evidence for appropriate prophylactic antibiotic regimens (e.g., studies testing antibiotic sensitivity in sinusitis patients) were also included ( Table 2). 5,8,[17][18][19][20][21][22][23][24][25][26][27][30][31][32][33][34][35] Studies that merely reported use of perioperative antibiotics for SES or associated postsurgical complications were excluded, as these reports neither provided rationale for antibiotic selection nor sought to specifically justify use of one antibiotic over another. [1][2][3][4]6,7,[10][11][12]14,16,[36][37][38]…”

Section: Search Outcomementioning

confidence: 99%

See 1 more Smart Citation

Rational Prophylactic Antibiotic Selection for Sinus Elevation Surgery

Akers

Hill

Kawaguchi

2019

Clin Adv Periodontics

View full text Add to dashboard Cite

Focused Clinical Question For a generally healthy patient with no risk indicators for postoperative infection, what is the most appropriate perioperative antibiotic regimen for sinus elevation surgery in terms of reducing postoperative infection risk and minimizing untoward effects? Clinical Scenario A 38‐year‐old female patient in good general and periodontal health presents missing tooth #14 (Fig. ). She reports no systemic conditions, no history of sinusitis, and no allergies. Medications include acetaminophen and ibuprofen as needed for pain. The patient's dentition is minimally restored, with no active caries. Cone‐beam computed tomography reveals a clear, pneumatized left maxillary sinus and inadequate bone volume to support dental implant placement (Fig. ). No septa or pathologic lesions are present, the ostium appears patent, and no thickening of the Schneiderian membrane is appreciable. The patient states that she wants to replace her missing molar without restoring adjacent teeth (Figs. and ). Baseline clinical appearance (example sinus elevation case). The patient is a healthy 38‐year‐old female missing tooth #14. Inadequate bone volume is present for dental implant placement due to pneumatization of the left maxillary sinus. Preoperative cone‐beam computed tomography images. 2a Sagittal view. 2b Coronal view. Cone‐beam computed tomography images at postoperative month 6. 3a Sagittal view. 3b Coronal view. Definitive implant‐supported restoration, tooth #14.

show abstract

Comparative In Vitro Activities of Amoxicillin-Clavulanate against Aerobic and Anaerobic Bacteria Isolated from Antral Puncture Specimens from Patients with Sinusitis

Cited by 18 publications

References 10 publications

Bacteriologic Findings Associated with Chronic Bacterial Maxillary Sinusitis in Adults

Bacteriologic Findings Associated with Chronic Bacterial Maxillary Sinusitis in Adults

A European Perspective on Topical Ophthalmic Antibiotics: Current and Evolving Options

Rational Prophylactic Antibiotic Selection for Sinus Elevation Surgery

Contact Info

Product

Resources

About