Comparative evaluation of Nano-Hydroxyapatite preparation and Calcium Sucrose Phosphate on microhardness of deciduous teeth after iron drop exposure - An in-vitro study

Rathi, Nilesh; Baid, Rutika; Baliga, Sudhindra; Thosar, Nilima

doi:10.4317/jced.53677

Cited by 13 publications

(21 citation statements)

References 11 publications

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“…In addition, apatite formed in an environment containing more calcium and phosphate is expected to contain less CO2 and less Mg by replacing them with calcium and phosphate, making enamel more acid resistant and increasing its surface hardness levels ( 12 ). This result is in agreement with Swarup JS et al ( 1 ), Rathi N et al ( 13 ), and Ebadifar A et al ( 7 ).…”

Section: Discussionsupporting

confidence: 92%

The effect of combining laser and nanohydroxy-apatite on the surface properties of enamel with initial defects

Assal¹,

Saafan²,

Moustafa³

et al. 2018

J Clin Exp Dent

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BackgroundThe aim of this study was to evaluate the effect of combining fractional CO2 LASER and nanohydroxy apatite on surface microhardness and color of enamel with initial defects.Material and MethodsTwo types of nano hydroxylapatite (nHAP) was prepared; Pure hydroxyapatite (nHA) and Fluoro hydroxyapatite (nFHA), Sixty extracted premolar teeth without visible caries or structural defects on enamel surface were used, immersed in 10 ml of a demineralizing solution for 2 weeks to create artificial white spot lesions, they were randomly allocated into two groups; Group 1: nHA, Group 2: nFHA, each group is then subdivided into 2 subgroups (A and B) where two different in vitroremineralization procedures have been performed, the first procedure utilizes a 10 wt% nHA aqueous slurries only, the second was first exposed to irradiation from a fractional CO2 laser then (nHAP) was applied. Microhardness and color were measured using a micro-Vickers hardness tester and spectrophotometer respectively.ResultsLaser treated teeth in both groups showed the highest mean hardness and lowest color difference where ΔE was less than 3.3 units, in both tests the pure type of nanohydroxyapatite gave better results than the nanofluroapatite type.ConclusionsNano-hydroxyapatite has remarkable remineralizing effects on initial lesions of enamel, certainly higher when combined with laser application. Key words:CO2 LASER, Enamel remineralization, Nanohydroxy apatite.

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Section: Discussionsupporting

confidence: 92%

The effect of combining laser and nanohydroxy-apatite on the surface properties of enamel with initial defects

Assal¹,

Saafan²,

Moustafa³

et al. 2018

J Clin Exp Dent

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“…22 Rani et al 23 and Thomas et al 24 demonstrated the superiority of CaSP in increasing the mean surface hardness as compared to CPP-ACP at 12th and 15th day of remineralization. Likewise, Rathi et al 7 also showed increase in mean microhardness of enamel after CaSP application.…”

Section: Microhardness Assessmentmentioning

confidence: 84%

“…An increase in the mean microhardness of enamel was evident in all the studies, post-application of CaSP. 6,7,12,14,[19][20][21][22][23][24] In addition, CaSP was also found to be effective in restoring the color of white spot lesion(s) and fluorotic enamel to that of normal enamel. 26 CaSP was also proven to be superior to other remineralizing agents in controlling the lesion depth.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of Remineralizing Efficacy of Calcium Sucrose Phosphate: A Systematic Review of In Vitro Studies

Karad

Dhole²

2019

J Indian Orthod Soc

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Background: Despite improved oral hygiene regime and availability of preventive formulations, dental caries continues to be a global dental problem. Calcium sucrose phosphate (CaSP) is a remineralizing agent with cariostatic action, which is commonly available in the form of tooth cream. Considering the paucity of evidence, this systematic literature review aims to evaluate the remineralizing efficacy of CaSP. Methodology: The review was conducted as per Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. Various databases, including PubMed, Cochrane Central, and Google Scholar, were searched until March 15, 2018 and were assessed for inclusion by two independent reviewers. The primary outcome was to assess the remineralizing efficacy of CaSP, and the secondary outcome was to assess the potential of CaSP in arresting white spot lesion(s) on enamel. Results: Out of 2,876 articles, only 13 were qualified for inclusion. Included studies presented a low risk of bias for the following items: caries-free teeth or restoration, and adherence to manufacture’s instruction for the usage of remineralizing agent in the risk of bias scale. Ten studies reported an increase in the microhardness of enamel after CaSP application, and three studies reported the effect of CaSP on arresting white spot lesion(s). CaSP was found to be a better remineralizing agent in comparison to casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), casein phosphopeptide-amorphous calcium phosphate with fluoride (CPP-ACPF) and other remineralizing agents in terms of increasing microhardness of enamel. In addition, CaSP application was also found to have a beneficial effect in restoring the color of white spot lesion(s) to that of normal enamel. Conclusion: CaSP tooth cream was found to be an effective remineralizing agent, compared to others, such as CPP-ACP and CPP-ACPF, in terms of increasing the mean microhardness of enamel and arresting white spot lesion(s).

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“…Hence, they have enhanced wettability which helps it to form a thin but strong layer on enamel surface that bonds to the tooth structure. [ 16 17 ] Finally, grape seed extract (GSE) has recently been advocated for its positive effects on the RML process of artificial carious lesions of the enamel in human primary teeth due to the GSE being rich in proanthocyanidin (PA), which is mainly composed of monomeric catechin and epicatechin, gallic acid, and polymeric and oligomeric procyanidins. PA has been reported to strengthen collagen-based tissues by increasing collagen cross-links.…”

Section: Introductionmentioning

confidence: 99%

Comparative evaluation of the remineralizing potential of commercially available agents on artificially demineralized human enamel: An In vitro study

et al. 2019

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Background: Caries is highly prevalent multifactorial disease, but its progression can be prevented in the initial stage of demineralization through remineralization (RML). Various materials have been proposed for the same, successful outcome can prove to be a boon in the prevention of caries. Aim: The aim of the study is to assess the RML potential of four commercially available agents so as to restore the enamel closest to its previous microhardness levels. Materials and Methods: Sixty permanent intact premolars were randomly divided into six groups: Four test groups – (1) bioactive glass (BAG) Novamin (SHY-NM), (2) nano-hydroxyapatite (nHAp) (Acclaim), (3) functionalized tricalcium phosphate (f-TCP) (Clinpro Tooth Crème), and (4) grape seed extract (GSE); one positive control – (5) fluoride (1000 ppm) containing dentifrice (Colgate Calci-Lock); and one negative control – (6) distilled water. The samples were initially evaluated for baseline surface microhardness (SMH); later on, these samples were placed in the demineralizing solution for 48 h in an incubator at 37°C, and postdemineralization again SMH was measured. Thereafter, the samples were subjected to the pH cycling for consecutive 21 days, and SMH was recorded. The SMH was evaluated using a Vickers microhardness tester. Statistical analysis was done using a post hoc Tukey test for each group based on the stage of treatment and one-way ANOVA for comparison among different groups. Results: BAG Novamin showed SMH recovery at 96.75% followed by f-TCP at 95.83%, nHAp at 90.88%, and GSE at 48.71%. Statistically significant differences were observed between the first three groups and the rest of the groups after RML stage. Conclusion: BAG Novamin, f-TCP, and nHAp showed considerable RML followed to a lesser extent by GSE.

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Comparative evaluation of Nano-Hydroxyapatite preparation and Calcium Sucrose Phosphate on microhardness of deciduous teeth after iron drop exposure - An in-vitro study

Cited by 13 publications

References 11 publications

The effect of combining laser and nanohydroxy-apatite on the surface properties of enamel with initial defects

The effect of combining laser and nanohydroxy-apatite on the surface properties of enamel with initial defects

Evaluation of Remineralizing Efficacy of Calcium Sucrose Phosphate: A Systematic Review of In Vitro Studies

Comparative evaluation of the remineralizing potential of commercially available agents on artificially demineralized human enamel: An In vitro study

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