Comparative Evaluation of Microhardness and Enamel Solubility of Treated Surface Enamel with Resin Infiltrant, Fluoride Varnish, and Casein Phosphopeptide-amorphous Calcium Phosphate: An In Vitro Study

Dhillon, Steffi N; Deshpande, Anshula; Macwan, Chirag; Patel, Kinjal S; Shah, Yatish T.; Jain, Aishwarya

doi:10.5005/jp-journals-10005-1833

Cited by 7 publications

(10 citation statements)

References 42 publications

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“…Regarding the EDX results, specimens treated with lactoferrin in both DM and PM groups revealed that the decline in Ca weight% was not statistically significant compared with a statistically significant reduction in the P weight%. Ca/P ratio also decreased with no statistical significance, explaining the decline in microhardness, which may be due to the breakdown of hydroxyapatite and loss of mineral content (calcium and phosphorus) [ 32 ]. Demineralization of enamel arises from chemical reactions that cause the major enamel component, hydroxyapatite crystals, to break down.…”

Section: Discussionmentioning

confidence: 99%

Effect of lactoferrin on enamel characteristics of primary and permanent teeth: an in-vitro study

Atia,

El-nemr,

Abo-Elsoud

2023

BMC Oral Health

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Background Lactoferrin, a glycoprotein naturally found in breast milk, is known for its bactericidal and antiviral properties, as well as its capacity to modulate the immune system; therefore, pediatricians routinely recommend it as dietary support. The objective of this study was to determine how lactoferrin oral suspension could affect the enamel surface characteristics of primary and permanent teeth. Methods This research was conducted on 40 unidentified extracted teeth, including primary and permanent teeth. Experimental teeth were free of cracks or enamel defects, as confirmed by careful examination using a dental operating microscope. The crowns were bisected into 80 specimens and assorted into two groups based on the type of dentition. Group DM included 40 specimens of second deciduous molars, while Group PM contained 40 samples of first premolars. Each of the DM and PM specimens was subsequently split based on the type of dispersion medium into two subgroups: a control subgroup (artificial saliva) and a test subgroup (lactoferrin suspension). The specimens were immersed in lactoferrin suspension for two minutes, then kept in artificial saliva for the rest of the 24 h for 30 successive days. This is a pioneering study about the effect of orally supplemented lactoferrin on teeth; therefore, we examined enamel hardness, ultra-morphology, and mineral contents. Results Our findings indicated a highly significant decrease (p < 0.01) in the microhardness of the lactoferrin subgroup in Group DM (second deciduous molars) and a significant reduction (p < 0.05) in the microhardness of the lactoferrin subgroup in Group PM (premolars). Calcium weight% was not statistically different (p > 0.05) compared with a significant decline (p < 0.05) in phosphorus weight% in lactoferrin subgroups in both DM and PM groups. The enamel surface of lactoferrin subgroups in both DM and PM groups was demineralized and porous, with the enamel of deciduous teeth being more affected by lactoferrin than permanent teeth. Conclusion Lactoferrin suspension decreased the microhardness of enamel and both calcium and phosphorus weight percentages. Both dentitions exhibited erosions in the enamel surface, with primary teeth being more affected than the permanent teeth.

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Section: Discussionmentioning

confidence: 99%

Effect of lactoferrin on enamel characteristics of primary and permanent teeth: an in-vitro study

Atia,

El-nemr,

Abo-Elsoud

2023

BMC Oral Health

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“…Other studies that have used the AFM analysis technique [ 42 , 43 , 44 ] have found that the hardness of dental hard tissues decreases after the use of fluoride varnishes. Additionally, fluoride varnish is effective in reducing enamel demineralization [ 45 , 46 ].…”

Section: Discussionmentioning

confidence: 99%

Xylitol Fluoride Varnish: In Vitro Effect Analysis on Enamel by Atomic Force Microscopy

et al. 2022

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(1) Background: Numerous studies have shown the beneficial role of fluoride in the primary prevention of dental caries. The aim of the present study was to put into evidence the change in the enamel structure immediately after the application of a fluoride varnish. (2) Methods: A xylitol–fluoride varnish was evaluated. The enamel specimens (n = 10) were analyzed by atomic force microscopy on enamel surface and treatment with fluoride varnish applied. The dimensional topographic analysis was performed by 2D and 3D analysis software. Statistical analysis was performed using SPSS Version 26.00 (IBM, Armonk, NY, USA). A one-sample statistics test was used to identify significant differences (p < 0.05). (3) Results: Surface roughness (Ra) measurements ranged from Ra = 0.039 μm (±0.048), to Ra = 0.049 μm (±0.031), respectively (p < 0.05), with an increase in the surface roughness passing from the intact enamel to the enamel exposed to fluoride varnish. When comparing Ra values of the nonfluorinated enamel and fluorinated enamel, significant differences (p < 0.05) were found, suggesting that the varnish had a protective effect on the enamel surface. (4) Conclusions: Xylitol–fluoride varnish, even in one single short-time application, is effective in reducing the surface roughness of enamel structure exposed to abrasion, thus increasing resistance to dental caries.

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“…The concern arises when discussing the treatment of superficial interproximal lesions, given the fact that restorative therapy involves removing a considerable amount of sound tissue, thus bringing the tooth into a circle of treatment and retreatment. 1 , 2 Currently, aiming at a minimally invasive and nondestructive odontology, various remineralizing agents could be indicated, such as dental hygiene instruction and fluoride topical application. However, these procedures are limited to the surface of the lesion, not being able to reach the demineralized tissue.…”

Section: Introductionmentioning

confidence: 99%

“…However, these procedures are limited to the surface of the lesion, not being able to reach the demineralized tissue. 1 In addition, requires the cooperation of patients to ensure successful treatment. 1 , 2 …”

Section: Introductionmentioning

confidence: 99%

“…The principle is to use a low-viscosity resin to penetrate the porosities of the demineralized surface through a capillary phenomenon, interrupting the demineralization process and paralyzing the carious lesion. 1 , 3 , 4 , 5 Icon® is the unique commercially available resin infiltrant in the market, is mainly composed of light-curable triethylene glycol dimethacrylate (TEGDMA) that allows the infiltration within the WSL by capillarity due to its wettability and viscosity to occlude its pores. 6 It is applied mainly to initial white spots, non-cavitated extending radiographically from all enamel to the outer third of dentin on smooth and proximal tooth surfaces.…”

Section: Introductionmentioning

confidence: 99%

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Radiopacity and physical properties evaluation of infiltrants with Barium and Ytterbium addition

Pedreira,

Damasceno,

Cerqueira

et al. 2023

Braz. Dent. J.

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Radiopaque properties in the infiltrant should be interesting for clinicians to feel more confident to indicate this treatment. Thus, the aim of this study was to evaluate the effect of the incorporation of barium and ytterbium particles on the physical properties of resin infiltrants. Groups were divided according to the addition of ytterbium oxide (Y) alone (30 or 40%) or Y with barium (YB) (15/15% or 20/20% respectively) in the Icon commercial infiltrant and in the experimental infiltrant base. Digital radiography (n=5), Microradiography (n=5), Microtomography (n=3), degree of conversion (n=5), water sorption (n=16), solubility (n=16), contact angle (n=16), flexural strength (n=16), elastic modulus (n=16) and Energy dispersive X-ray Spectroscopy (n=10) were performed. Analyses were performed using the R program, with a significance level of 5%, and microradiography and Microtomography analyses were evaluated qualitatively. In groups with 30 or 40% of ytterbium, radiopacity was higher or equal to enamel. Microradiography and Microtomography appear to have more radiopacity in groups with 40% (Y). Among the groups with no particle addition, those of the experimental infiltrant presented a higher degree of conversion than those of Icon®. In most groups, there was solubility below the ISO-recommended levels. The addition of particles resulted in higher viscosity. Groups with Icon had higher flexural strength and elastic modulus than groups with experimental infiltrant. The addition of 40% (Y) improved polymerization, had low solubility, and had greater radiopacity than enamel, however negatively affected the viscosity increasing then. Experimental groups with the base showed a higher water sorption than Icon groups.

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Comparative Evaluation of Microhardness and Enamel Solubility of Treated Surface Enamel with Resin Infiltrant, Fluoride Varnish, and Casein Phosphopeptide-amorphous Calcium Phosphate: An In Vitro Study

Cited by 7 publications

References 42 publications

Effect of lactoferrin on enamel characteristics of primary and permanent teeth: an in-vitro study

Effect of lactoferrin on enamel characteristics of primary and permanent teeth: an in-vitro study

Xylitol Fluoride Varnish: In Vitro Effect Analysis on Enamel by Atomic Force Microscopy

Radiopacity and physical properties evaluation of infiltrants with Barium and Ytterbium addition

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