Comparative Evaluation of Hair Density and Grouped Hair Unit Pattern between Androgenetic Alopecia and Normal Scalp

Han, Seung Seog; Park, Yong‐Tae; Yoo, Jae Hak; Park, Tae Ho; Kim, Kea Jeung

doi:10.5021/ad.2004.16.1.1

Cited by 3 publications

(1 citation statement)

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“…The occipital and vertex scalp may present different skin micro-environment to the microbiome as they originate from different embryonic developmental plates and are exposed to varying degrees of solar irradiation. AGA patients typically feature a patterned baldness whereby lower hair density, hair thinning and yellow dots depicting enlarged sebaceous glands in response to androgen are evident in the vertex scalp area [43, 44]. Despite the changes, the microbiome in AGA patients did not differ significantly between different sites on the scalp; nor was it significantly unique according to individual age and AGA severity.…”

Section: Discussionmentioning

confidence: 99%

Microbiome in the hair follicle of androgenetic alopecia patients

Chu

et al. 2019

PLoS ONE

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Androgenetic alopecia is the most common form of hair loss in males. It is a multifactorial condition involving genetic predisposition and hormonal changes. The role of microflora during hair loss remains to be understood. We therefore analyzed the microbiome of hair follicles from hair loss patients and the healthy. Hair follicles were extracted from occipital and vertex region of hair loss patients and healthy volunteers and further dissected into middle and lower compartments. The microbiome was then characterized by 16S rRNA sequencing. Distinct microbial population were found in the middle and lower compartment of hair follicles. Middle hair compartment was predominated by Burkholderia spp . and less diverse; while higher bacterial diversity was observed in the lower hair portion. Occipital and vertex hair follicles did not show significant differences. In hair loss patients, miniaturized vertex hair houses elevated Propionibacterium acnes in the middle and lower compartments while non-miniaturized hair of other regions were comparable to the healthy. Increased abundance of P . acnes in miniaturized hair follicles could be associated to elevated immune response gene expression in the hair follicle.

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Section: Discussionmentioning

confidence: 99%

Microbiome in the hair follicle of androgenetic alopecia patients

Chu

et al. 2019

PLoS ONE

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A new practical classification for spatial distribution and morphology of human hair: Ahmad'sLGMAclassification

Malik¹

2017

J of Cosmetic Dermatology

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Hair characteristics and androgenetic alopecia in Koreans

Choi

2013

J Korean Med Assoc

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T he scalp hair is composed of one hundred thousand of hairs. Each hair goes through the three phases of the hair cycle, which causes the hair to turn from an anagen hair into a catagen hair, then into a telogen hair, and finally into a new anagen hair. The number of hairs is maintained at a relatively constant level because each hair has its own hair cycle. The hair of Koreans is relatively thicker than that of Caucasians and Africans but its growth rate and density are lower. There are various factors that influence hair growth such as hormones, nutritional status, and drugs. However, androgen is most important among these factors and, particularly, androgenetic alopecia is caused by androgen and genetic factors. Because excessive dihydrotestosterone produced by 5α-reductase is of the greatest importance in androgenetic alopecia, finasteride or dutasteride, which inhibits the action of 5α-reductase, is effective in treating androgenetic alopecia. Also, minoxidil is widely used as it promotes hair growth. Furthermore, there are various types of hair diseases and specialized examination is required for differential diagnosis.

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Comparative Evaluation of Hair Density and Grouped Hair Unit Pattern between Androgenetic Alopecia and Normal Scalp

Cited by 3 publications

References 0 publications

Microbiome in the hair follicle of androgenetic alopecia patients

Microbiome in the hair follicle of androgenetic alopecia patients

A new practical classification for spatial distribution and morphology of human hair: Ahmad'sLGMAclassification

Hair characteristics and androgenetic alopecia in Koreans

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