Comparative Evaluation of Efficacy of Use of Tamsulosin and/or Tolterodine for Medical Treatment of Distal Ureteral Stones

Erturhan, Sakıp; Erbağcı, Ahmet; Yağcı, Faruk; Çelik, Mehmet Ali; Solakhan, Mehmet; Sarıca, Kemal

doi:10.1016/j.urology.2007.01.009

Cited by 69 publications

(52 citation statements)

References 21 publications

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“…The combined search strategies identified 29 trials [6,9,10,11,12,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38], including 2,763 patients (1,051 tamsulosin 0.4 mg/day, 145 tamsulosin 0.2 mg/day and 1,567 controls), that met the inclusion criteria. One of the studies was written in Korean [26] and another in Chinese [38].…”

Section: Resultsmentioning

confidence: 99%

Tamsulosin for Ureteral Stones: A Systematic Review and Meta-Analysis of a Randomized Controlled Trial

Dong

Ding

et al. 2012

Urol Int

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Background/Aims: To evaluate the efficacy of tamsulosin as a medical expulsive therapy of ureteral stones. Methods: We searched PubMed, EMBASE, the Cochrane Library, and ISI-Science Citation Index up to December 2011. All randomized controlled trials were identified in which patients were randomized to receive either tamsulosin or standard therapy with/without placebo for ureteral stones. Outcome measures assessed were overall stone expulsion rate (primary) and expulsion time, and the number of pain episodes (secondary). Three authors independently assessed study quality and extracted data. All data were analyzed using RevMan 5.0. Results: Twenty-nine trials with a total of 2,763 patients met the inclusion criteria. The pooled analysis showed a 19% improvement in stone clearance with tamsulosin. According to the doses of tamsulosin, the pooling effects of tamsulosin were analyzed, with a higher expulsion rate obtained than in controls. Compared with calcium channel blockers, there was a higher stone expulsion rate in tamsulosin. In addition, a shorter expulsion time, fewer colic episodes and adverse effects were observed. Conclusions: Tamsulosin is a safe and effective medical expulsive therapy choice for ureteral stones. It should be recommended for most patients with distal ureteral stones before stones are 10 mm in size. In future, high-quality multicenter, randomized and placebo-controlled trials are needed to evaluate the outcome.

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Section: Resultsmentioning

confidence: 99%

Tamsulosin for Ureteral Stones: A Systematic Review and Meta-Analysis of a Randomized Controlled Trial

Dong

Ding

et al. 2012

Urol Int

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“…La posibilidad de expulsión espontánea del cálculo depende esencialmente de su tamaño y localización, la estenosis del uréter en su anatomía interna. La historia de expulsión espontánea y la posible causa de retención de cálculos son el espasmo, el edema y la infección ureteral 2,21 . Se menciona que, en una obstrucción completa, los signos de daño renal aparecen a las 3 o 4 semanas.…”

Section: Discussionunclassified

Uso de alfuzosina para la expulsión de cálculos del tercio distal del uréter

Morúa¹,

García²,

Montelongo³

et al. 2009

Actas Urol Esp

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“…Only 4 studies had a low risk of bias, 14,27,33,36 7 had a moderate risk of bias, 24,25,30,32,34,35,38,40 and 11 had a high risk of bias 23,26,28,29,31,37,39,[41][42][43] (Figure 2). A poor description of the randomization process is mainly responsible for the high proportion of moderate or high risk of bias studies.…”

Section: Methodological Qualitymentioning

confidence: 99%

“…Studies were written in English 14,[23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41] and Korean. 42,43 Most articles compared tamsulosin to standard therapy alone (NSAIDs + hydration 6 opioids).…”

Section: Literature Searchmentioning

confidence: 99%

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Tamsulosin for treatment of unilateral distal ureterolithiasis: a systematic review and metaanalysis

Malo

Audette-Côté

Émond

et al. 2014

CJEM

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Objectives: The lifetime prevalence of ureterolithiasis is approximately 13% for men and 7% for women in the United States. Tamsulosin, an a-antagonist, has been used as therapy to facilitate the expulsion of lithiasis. Whether it is a good treatment for distal lithiasis remains controversial. We conducted a systematic review and meta-analysis to evaluate the effect of tamsulosin on the passage of distal ureterolithiasis. Methods: A systematic search was conducted using MEDLINE, EMBASE, and Cochrane Central. Trial eligibility was evaluated by two investigators. All randomized controlled trials (RCTs) comparing tamsulosin to standard therapy or placebo for the treatment of a single distal ureterolithiasis # 10 mm in adult patients with renal colic confirmed by radiographic imaging were included. Data extraction was conducted in duplicate. Primary outcome was the expulsion rate, and secondary outcomes were the mean time for ureterolithiasis expulsion, analgesic requirements, and side effects. Mantel-Haenszel random effect models were used, and heterogeneity was assessed using I 2 statistics. Data were presented with relative risks (RRs). Results: The search strategy identified 685 articles, of which 22 studies were included. Combined results suggested a benefit for the expulsion of ureterolithiasis (# 10 mm) when tamsulosin was used compared to a standard treatment (RR 1.50 [95% CI 1.31-1.71], I 2 5 70%). A decrease in the average time of expulsion of the ureterolithiasis of 3.33 days in favour of tamsulosin was observed (95% CI 24.23, 22.44], I 2 5 67%). Conclusion: Tamsulosin increases the rate of spontaneous passage of distal ureterolithiasis (# 10 mm). RÉ SUMÉObjectif: La pré valence de la lithiase uré té rale au cours de la vie est d'environ 13% chez les hommes et 7% chez les femmes aux É tats-Unis. La tamsulosine, un alpha-bloquant, est utilisé e comme traitement pour faciliter l'expulsion des calculs; toutefois, le recours à ce traitement dans la lithiase distale fait l'objet de controverse. Nous avons donc mené un examen mé thodique et une mé ta-analyse afin d'é valuer l'effet de la tamsulosine sur le passage des lithiases uré té rales distales. Mé thode: Une recherche mé thodique a é té effectué e dans les bases de donné es MEDLINE, EMBASE, et Cochrane Central, et l'acceptabilité des essais a é té soumise à l'examen de deux chercheurs. Ont é té retenus tous les essais comparatifs, à ré partition alé atoire, visant à mettre en parallè le la tamsulosine avec les procé dé s thé rapeutiques habituels ou avec un placé bo dans le traitement d'une seule lithiase uré té rale distale,# 10 mm, confirmé e à la radiographie, chez des adultes souffrant de colique né phré tique. L'extraction des donné es a é té ré alisé e en double. Le principal critè re d'é valuation é tait le taux d'expulsion, et les critè res d'é valuation secondaires portaient sur le temps moyen é coulé avant l'expulsion des lithiases uré té rales, l'administration d'analgé siques, et les effets indé sirables. Nous avons eu recours aux modè...

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Comparative Evaluation of Efficacy of Use of Tamsulosin and/or Tolterodine for Medical Treatment of Distal Ureteral Stones

Cited by 69 publications

References 21 publications

Tamsulosin for Ureteral Stones: A Systematic Review and Meta-Analysis of a Randomized Controlled Trial

Tamsulosin for Ureteral Stones: A Systematic Review and Meta-Analysis of a Randomized Controlled Trial

Uso de alfuzosina para la expulsión de cálculos del tercio distal del uréter

Tamsulosin for treatment of unilateral distal ureterolithiasis: a systematic review and metaanalysis

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