Uso de alfuzosina para la expulsión de cálculos del tercio distal del uréter

Morúa, Alejandro García; García, José Antonio Guevara; Montelongo, Rafael Martínez; Guerra, Lauro Salvador Gómez

doi:10.4321/s0210-48062009000900013

Cited by 3 publications

(1 citation statement)

References 25 publications

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“…There are different treatment options including conservative management, shock wave lithotripsy (SWL) and ureteroscopy (URS). Advancement in minimally invasive surgery has resulted in widespread acceptance of ESWL and URS are very efficient modalities with success rates ranging from 63-86% and 57-92% respectively [19][20][21] . Nevertheless both these interventions are associated with complications and are expensive.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous Expulsion of Lower Ureteric Stones in Patients with Elevated Level of C-Reactive Protein

Hamid¹,

Ali²,

Ullah³

et al. 2022

PJMHS

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Background: Around 4–15% of people worldwide have urolithiasis, and ureteric stones account for around 20% of this condition. One of the most frequent situations a urologist has to deal with is acute renal colic caused by urolithiasis. Objective: To determine the spontaneous expulsion of lower ureteric stones in patients with elevated level of c-reactive protein Methodology: This descriptive cross sectional study was performed at the urology department Khalifa Gul Nawaz Teaching Hospital, Bannu Medical College Bannu for a period of six months from January 2022 to June 2022. A total of 210 patients were included in the study using non probability consecutive sampling. All patients had lower ureteric stone and raised CRP. Patients were followed till spontaneous expulsion or stone clearance. Data was analyzed using IBM SPSS version 23. Results: A total of 210 patients were enrolled in this study. There were 112(53.33%) were female and 98(46.67%) were male. Patients included in the study had age range from 18- 60yr,mean age was 34.32±7.92 SD. Patients selected in the study had lower ureteric stones ranging from 5-9mm. mean stone size was 6.990 mm ±0.92 SD. Mean CRP was 3.36 mg/dl ±1.99 SD. 50 (31.25%) patients with CRP 0.5-4.9mg/dl passed stones spontaneously while 45 (90%) patients with CRP 5-9.9 mg/dl passed stone spontaneously. Conclusion: Serum CRP is a relatively newer marker now increasingly being used for the purpose of predicting spontaneous stone expulsion of small lower ureteric stones. However current evidence still does not support CRP levels alone to be recommended for this purpose. Clinical assessment of every individual patient is still the mainstay of decision for intervention. Keywords: Spontaneous expulsion; lower ureteric stones; c-reactive protein

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Section: Discussionmentioning

confidence: 99%

Spontaneous Expulsion of Lower Ureteric Stones in Patients with Elevated Level of C-Reactive Protein

Hamid¹,

Ali²,

Ullah³

et al. 2022

PJMHS

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Efficacy of Alfuzosin Versus Control Group in Upper Ureteric Stone Expulsion in Adult Population of Lahore, Pakistan

Humayun¹,

Mujtaba²,

Seerwan³

et al. 2022

GJMS

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Background: Urinary stone disease is one of the commonest urological diseases worldwide. The objective of this study was to compare the efficacy of alfuzosin versus control group in upper ureteric stone expulsion in adult population of district Lahore, Pakistan.Materials Methods: This trial was conducted in Department of Urology, Sheikh Zayed Hospital, Lahore, Pakistan form January 2017 to June 2017. All adult patients with upper ureteric stone size 5-10 mm were eligible. Those with multiple stones, having fever, severe pain, history of surgery in past two weeks and growth on urine culture or pyuria were excluded. Experimental and control groups each had 30 patients. Experimental group received Tab. alfuzosin 10 mg daily for four weeks and Tab. diclofenac sodium 50 mg SOS for acute pain. The control group received Tab. diclofenac sodium 50 mg SOS for acute pain. We followed all patients for four weeks for expulsion of ureteric stones by X-ray KUB or CT KUB. Sex, age and stone size were matching variables. Stone expulsion (yes, no) was research variable. We compared count of stone expulsion between two groups by using McNemar chi-square test at alpha 0.5 using GraphPad.Results: Out of 30 patients in experimental group, 23 (76.67%) were men and seven (23.33%) women and out of 30 in control group, 20 (66.67%) were men and 10 (33.33%) women, almost similar in both groups. Mean age in experimental group was 39.45±10.33 years and in control group it was 37.38±8.28 years, almost similar in both groups. Mean stone size was 7.45±1.47 (5-10) mm in the experimental and 7.28±1.68 (5-10) mm in control group, being comparable in both the groups. In experimental group, stone expulsion was achieved in 23 (76.67%) cases and not in seven (23.33%) cases and in control group, it was achieved in 16 (53.33%) cases and not in 14 (46.67%) cases. There was statistically no significant difference in efficacy of alfuzosin versus control group (p=.1213).Conclusion: Our study showed no difference in efficacy of alfuzosin versus control group for upper ureteric stone expulsion in adult population of district Lahore, Pakistan.

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Efficacy of Doxazosin Versus Tamsulosin in Lower Ureteric Stone Expulsion in Adult Population of District Dera Ismail Khan, Pakistan

Seerwan

Khan

Ilyas

et al. 2021

GJMS

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Background: Urolithiasis is the third common disease of the urinary tract after UTIs and pathological diseases of the prostate. The objective of this study was to compare the efficacy of doxazosin versus tamsulosin in lower ureteric stone expulsion in adult population of District Dera Ismail Khan, Pakistan.Materials Methods: This non-randomized control trial was conducted in the Department of Urology, Gomal Medical College, Dera Ismail Khan, Pakistan from February 2020 to December 2020. The 252 patients included in our study were divided in to two groups. The patients in experimental group received Tab. doxazosin 4 mg daily for 4 weeks and Tab. diclofenac sodium 50 mg B.D for 5 days and then on need basis. The patients in control group received Cap. tamsulosin 0.4 mg daily for 4 weeks and similarly Tab. diclofenac sodium 50 mg as in experimental group. All the patients were followed regularly for expulsion of ureteric stones for four weeks. Sex, age and stone size were matching, while stone expulsion was a research variable. Hypothesis was verified by McNemar chi-square test.Results: Out of 252 patients, 113 (89.68%) patients in experimental group, while 77 (61.11%) patients in control group passed the stones. There was statistically significant difference in efficacy in doxazosin group as compared to tamsulosin group (p-value=.0001).Conclusion: The use of doxazosin as the medical expulsion therapy for the lower ureteric stone proved to be more effective as compared to tamsulosin as demonstrated by our results.

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Uso de alfuzosina para la expulsión de cálculos del tercio distal del uréter

Cited by 3 publications

References 25 publications

Spontaneous Expulsion of Lower Ureteric Stones in Patients with Elevated Level of C-Reactive Protein

Spontaneous Expulsion of Lower Ureteric Stones in Patients with Elevated Level of C-Reactive Protein

Efficacy of Alfuzosin Versus Control Group in Upper Ureteric Stone Expulsion in Adult Population of Lahore, Pakistan

Efficacy of Doxazosin Versus Tamsulosin in Lower Ureteric Stone Expulsion in Adult Population of District Dera Ismail Khan, Pakistan

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