Comparative Evaluation of Bioactive Synthetic NovaBone Putty and Calcified Algae-derived Porous Hydroxyapatite Bone Grafts for the Treatment of Intrabony Defects

Abstract

IntroductionTo compare and evaluate clinically and radio-graphically the bone regeneration and the amount of bone fill in intrabony component of periodontal osseous defects through the osteoconductive and osteostimulative effect of bioactive synthetic NovaBone Putty - CMF and osteoconductive effect of calcified algae-derived porous hydroxyapatite Frios® Algi-pore® bone grafts.Materials and methodsTwenty-two sites in 11 patients, within the age range of 25 to 60 years, showing intrabony defects were selected according to split mouth design and divided into group I (Frios® Algipore®) and group II (NovaBone Putty - CMF). All the selected sites were assessed with the clinical and radiographic parameters like plaque index, gingival index (full mouth and site specific), sulcus bleeding index, probing pocket depth, clinical attachment level, gingival recession, and radiographic bone fill. All the clinical and radiographic parameter values obtained at different intervals (baseline, 3, and 6 months) were subjected to statistical analysis.ResultsA statistically significant reduction in pocket depth of 2.55 ± 0.52 mm (group I), 2.64 ± 0.67 mm (group II) and gain in clinical attachment level of 7.55 ± 1.44 mm (group I), 7.55 ± 2.38 mm (group II) were recorded at the end of the study. A slight increase in gingival recession was observed. The mean percentage change in amount of radiographic bone fill of group II (71.34%) was more than group I (61.93%).ConclusionBoth NovaBone Putty - CMF and Frios® Algipore® improve healing outcomes and lead to a reduction of probing depth, a resolution of osseous defects, and a gain in clinical attachment, but radiographic observation found better results with NovaBone Putty.How to cite this articleBembi NN, Bembi S, Mago J, Baweja GK, Baweja PS. Comparative Evaluation of Bioactive Synthetic NovaBone Putty and Calcified Algae-derived Porous Hydroxyapatite Bone Grafts for the Treatment of Intrabony Defects. Int J Clin Pediatr Dent 2016;9(4):285-290.

Management of Dehiscence During Implant Placement With Sandwich Technique: A Case Report.

“…Histological examination of the treated sites showed ossification of the implant pores and the implant periphery. 25 Bowen et al 26 also found that this graft material offers the potential for increasing new bone mass. A collagen membrane was trimmed and used to contain the bone grafts and also exclude the non-regenerative cells, such as epithelial cells from colonizing the site.…”

Application of 4MATRIX and PRF in the Treatment of Infrabone Defects in Chronic Periodontopathy

“…In the last twenty years, periodontal therapy has progressed significantly, from formerly used resective methods, to principles of preservation and regeneration of periodontal tissues which are used today Bembi et al, found no significant difference in the results of treatment with two materials, NovaBone Putty– CMF, and Frios Algipore, followed by clinical parameters of probe depth and clinical attachment level ( 12 ).…”

Socket Shield and Bioactive Glass Around Anterior Maxilla Immediate Dental Implants

“…Also, Barakat et al 5 found that this technique maintained the buccal bone plate, and Mitsias et al 6 The third generation bioactive glass, calcium phosphosilicate, utilized in this study was proven to result in vital bone formation after a 4 to 5 months healing period and tended to increase over time as found by Kesmas et al, 15 Kotsakis et al, 17,18 and Gonshor et al 19 who reported that this relatively fast healing may provide a clinical advantage for implant osseointegration. In addition, the findings of Bembi et al 20 revealed that the bioactive calcium phosphosilicate was biocompatible and safe to use without causing any inadvertent tissue response or antigenic reaction for the treatment of intra bony defects once good oral hygiene and inflammationfree periodontal tissue were maintained in the postoperative phase. These findings were further confirmed by Mahesh et al 21,25 and Babbush and Kanawati 22 who have shown that this bioactive glass paste consistency allowed faster and proper filling of the peri implant defects.…”

“…[9][10][11][12][13][14] The osteostimulative properties of bone graft materials can lead to new bone formation within 4-6 months of healing and tend to increase over time which is ideal to ensure good quality of bone and sufficient thickness of the overlying soft tissue for long-term implant survival. [15][16][17][18][19][20][21][22][23][24][25] Compared to delayed implants, immediate implants in the anterior maxilla encounter some adverse esthetic outcomes resulting from labial plate resorption and gingival recession. [26][27][28] However, improved implant macro-mechanical design, and surface treatments that can ensure long term biointegration, were found to minimize such complications in carefully selected patients.…”