Comparative epidemiology of rotavirus, subgenus F (types 40 and 41) adenovirus, and astrovirus gastroenteritis in children

Abstract

We report a 5 year prospective study of episodes of rotavirus, subgenus F adenovirus, and astrovirus gastroenteritis diagnosed by electron or immune electron microscopy in a single regional virology laboratory. Of 1426 total infections, the numbers in each category were 1117 (78.3%), 254 (17.8%), and 20 (7.9%), respectively. Using restriction endonuclease analysis or immune electron microscopy, all but 20 of the subgenus F adenovirus strains were classified as type 40 (n = 50) or type 41 (n = 184). Rotavirus and astrovirus infections were more prevalent in winter than summer, whereas subgenus F (either type 40 and 41) adenoviruses showed no seasonal variation in prevalence. The ratio of type 40 to all typable subgenus F adenoviruses declined between 1984 and 1986 and then increased again. Adenoviruses were relatively more important as causes of viral gastroenteritis in infants aged less than 6 months than in toddlers aged 12 months or more, but even in young infants more rotavirus than adenovirus infections were diagnosed. Our data confirmed the epidemiological differences between rotavirus, subgenus F adenovirus and rotavirus gastroenteritis and documented the shared epidemiological characteristics of type 40 or 41 adenovirus infections.

Investigation of the Enteric Adenovirus Antigen Frequency by Immunochromotographic Method in Children with Acute Gastroenteritis

“…In our study, adenovirus was found in 102 stool samples from 3206 (3.2%) which falls slightly below the national and world average. It has been reported that although it is slightly more common in the summer, gastroenteritis caused by adenovirus may occur in a large part of the year (2,5,9). In studies performed in our country, Akıncı et al (10) found that the adenovirus-related gastroenteristis was seen equally throughout the year, a little more often in the summer.…”

“…It has been shown that adenovirus was the most common cause of gastroenteritis in children under 2 years of age (7,12). Bates et al (9) found that 50% of children with adenovirus-detected gastroenteritis were under 2 years of age, Hazar et al (12) reported that 35% of children infected with adenovirus were aged 6-11 months and 35% were 1-2 years of age. Gül et al (7) found that 57.1% of children were 1-2 years and 28.6% were 0-1 years of age.…”

Ocorrência de adenovirus em crianças com gastrenterite aguda grave na Cidade de Belém, Pará, Brasil

“…Este discreto aumento de AdE en marzo, puede ser asociado, tal vez, al mayor índice de precipitación pluviométrica en la región. Cabe destacar, sin embargo, que no hay evidencia de estacionalidad para este virus en diversas investigaciones llevadas a cabo en países de clima templado, en donde se configuró el carácter endémico de 23,24,25 la infección . En Rio de Janeiro y en Bahia tampoco se 21 observó variación estacional significativa .…”

Adenovirus infection in children with diarrhea disease in Northwestern Nigeria

“…7 In Nigeria, few available studies conducted in the Southern and Northcentral regions have associated adenoviruses with 3.8% 9 and 6.7% 10 of pediatric diarrhea. In Northwestern Nigeria, there is no published information on the epidemiology of EAds which some studies [11][12][13] have implicated as the second most important viral agent associated with gastroenteritis in children. This study was therefore conducted to investigate the epidemiology of human enteric adenoviruses associated with gastroenteritis in children 0-5 years old in Northwestern Nigeria.…”