Comparative effects of antihistamines on aircrew mission effectiveness under sustained operations.

Eddy, Douglas R.; Dalrymple, Mathieu A.; Schiflett, Samuel G.

doi:10.1037/e454472004-001

Cited by 3 publications

(3 citation statements)

References 12 publications

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“…43 The effectiveness of H1 antagonistic antihistamines have been put to question as a counteragent to motion sickness in aircrew. 44 The results of this study indicate that not only may they be inefficient, they could potentially be counterproductive in that they enhance motion sensitivity.…”

Section: Visual-vestibular Responsementioning

confidence: 79%

The effects of meclizine on motion sickness revisited

Wibble

Engström

Verrecchia

et al. 2020

Brit J Clinical Pharma

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Antihistamines make up the first line of treatments against motion-sickness. Still, their efficacy and specific mechanism have come into question. The aim of this study was to investigate the effect of meclizine on motion-sensitivity. Methods: This study was carried out as a triple-blinded randomized trial involving 12 healthy subjects who were exposed to (i) vestibular (VES), (ii) visual (VIS) and (iii) visual-vestibular (VIS+VES) stimulations in the roll plane. Subjects were divided into 2 groups by stratified randomization, receiving either meclizine or a placebo. Stimulations were carried out before, and after, drug administration, presented at 2 intensity levels of 14 and 28 /s 2. Eye movements were tracked, and torsional slowphase velocities, amplitudes and nystagmus beats were retrieved. Subjects initially graded for their motion-sickness susceptibility. Results: Susceptibility had no effect on intervention outcome. Despite large variations, repeated ANOVAS showed that meclizine led to a relative increase in torsional velocity compared to placebo during vestibular stimulation for both intensities: 2.36 (7.65) from −0.01 (4.17) during low intensities, and 2.61 (6.67) from −3.49 (4.76) during high. The visual-vestibular stimuli yielded a decrease during low acceleration,

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Section: Visual-vestibular Responsementioning

confidence: 79%

The effects of meclizine on motion sickness revisited

Wibble

Engström

Verrecchia

et al. 2020

Brit J Clinical Pharma

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“…Their main side-effect is drowsiness. In addition, they have been shown to have serious negative influences on a broad range of human performance tasl,:• including reaction time, tracking, continuous memory, visual search, digit symbol, divided attention, and vigilance (see Eddy, Dalrymple, and Schiflett, 1992; for brief reviews).…”

Section: Other Drugsmentioning

confidence: 99%

Readiness to Perform testing: A critical analysis of the concept and current practices.

Gilliland¹,

Schlegel²

1993

PsycEXTRA Dataset

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“…First, we focused on conceptualization, description, and measurement of individual performance (Klinger et al, 1993). At the same time, we initiated investigations related to team performance and dynamic environments (Dalrymple, Eddy, & Schiflett, 1995;Dalrymple & Schiflett, 1997;Eddy, 1989;Eddy, et al, 1992;Elliott, Serfaty, & Schiflett, 1998;Elliott, Schiflett, & Dalrymple, 1998;Fahey et al, in review;MacMillan, et al, 1998;Schiflett & Elliott, in review;Schiflett, et al, 1990). Finally, we are investigating various methods to model performance (Cobb et.…”

Section: Introductionmentioning

confidence: 99%

Simulation-based Agent Support in a Synthetic Team-based C2 Task Environment

Elliott¹,

Chaiken²,

Dalrymple³

et al. 2000

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In our long-term program of research in command and control (C2) teamwork and performance, we have extensively analyzed the roles, responsibilities, and interdependencies of Airborne Warning and Control System (AWACS) Weapons Director (WD) teams, using a variety of methods. The AWACS WD team serves as a vital airborne C2 node, providing airborne surveillance and command, control, and communications functions for tactical and air defense forces. They detect, identify, track, and intercept airborne threats. Our investigations seek to identify tools and techniques to facilitate performance in this complex and dynamic domain. In this paper, we describe progress toward an agent-based decision support system, the AWACS WD Intelligent Agent Assistant (IAA). The WD-IAA will facilitate decision making for decision events which are both typical and time consuming. This paper will describe approach, methodology, and potential application areas for agent-technologies in C2 training. Report Documentation Page Form Approved OMB No. 0704-0188Public reporting burden for the collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden, to Washington Headquarters Services, Directorate for Information Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to a penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number.

show abstract

Comparative effects of antihistamines on aircrew mission effectiveness under sustained operations.

Cited by 3 publications

References 12 publications

The effects of meclizine on motion sickness revisited

The effects of meclizine on motion sickness revisited

Readiness to Perform testing: A critical analysis of the concept and current practices.

Simulation-based Agent Support in a Synthetic Team-based C2 Task Environment

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