Comparative Cost Effectiveness of Varicella, Hepatitis A, and Pneumococcal Conjugate Vaccines

The cost-effectiveness of universal vaccination of children against hepatitis A in Argentina: results of a dynamic health–economic analysis

“…3,20,22,23,25,27,44,46 Real case studies, such as those from Israel, 19,23 the United States, 15,39 and Argentina, 3,33 are needed to improve understanding of the factors that affect cost-effectiveness and to provide model cases in order to facilitate future healthcare decision-making.…”

Regional variation in the cost effectiveness of childhood hepatitis A immunization

“…With adjustments reflecting the current study methods, varicella and pneumococcal conjugate vaccines cost the health system $26 400 and $74 800 per life-year saved, respectively. 51 Hepatitis B immunization of infants costs the health system $20 600 per life-year saved. 53 We found that hepatitis A vaccination would provide greater health benefits to personal contacts than to vaccinees themselves.…”

“…12 were adjusted to 2002 values using a 3% annual discount rate, 12 considering the interval between age 2 years and hepatitis A cost, disability or death. 51 Sensitivity analyses were conducted to examine the effect of selected assumptions on the primary endpoint. To consider alternative time preferences, discount rates of 0 and 5% were substituted.…”

Universal vaccination of children against hepatitis a in Chile: a cost-effectiveness study

“…4 There are also indirect costs associated with work absenteeism and lost productivity, which can add to the societal burden of hepatitis A. Targeted or routine vaccination against hepatitis A can be costeffective or even cost saving in some, but not all, situations (24)(25)(26)(27)(28)(29)(30). For example, routine childhood vaccination can be highly effective (13,17,31) and cost-effective (26,32) in countries or regions with decreasing levels of endemicity, such as Argentina, Israel, and the United States.…”