Comparative chromosome painting discloses homologous segments in distantly related mammals

Scherthan, Harry; Cremer, Thomas; Árnason, Úlfur; Lima-de-Faria, A.; Frönicke, Lutz

doi:10.1038/ng0494-342

Cited by 262 publications

(154 citation statements)

References 46 publications

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“…Comparative chromosome painting is a robust method for detecting chromosome homologies at the whole chromosome level, and this approach provides clues about the processes of karyotypic evolution (Wienberg et al 1990, Scherthan et al 1994, Wienberg & Stanyon 1995. The 5S and 18S-28S ribosomal RNA (rRNA) genes are good cytogenetic markers to examine interand intraspecies chromosomal variations, and in our previous study, we defined the chromosome rearrangements between the laboratory mouse (Mus musculus) and the Indian spiny mouse (M. platythrix) by comparative chromosome painting and mapping of the rRNA genes (Matsubara et al 2003).…”

Section: Introductionmentioning

confidence: 99%

Karyotypic Evolution of Apodemus (Muridae, Rodentia) Inferred from Comparative FISH Analyses

et al. 2004

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SummaryWe conducted comparative FISH analyses to investigate the chromosomal rearrangements that have occurred during the evolution of the rodent genus Apodemus, which inhabits broadleaf forests in the temperate zone of the Palaearctic region. Chromosome-specific painting probes of the laboratory mouse were hybridized to chromosomes of seven Apodemus species, A. agrarius, A. argenteus, A. gurkha, A. peninsulae, A. semotus, A. speciosus and A. sylvaticus, and homologous chromosomal regions were determined in the species for the study of karyotypic evolution. Differences in the hybridization patterns were found in nine pairs of autosomes among the seven species. The chromosomal location of the 5S rRNA genes on the telomeric region of chromosome 20 was highly conserved in all the species. In contrast, there was much wider variation in the location of the 18S-28S rRNA genes, although the 18S-28S rRNA genes were predominantly located on chromosomes 7, 8 and 12. Phylogenetic relationships of the seven Apodemus species were inferred from the chromosome rearrangements and the chromosomal distribution patterns of the 18S-28S rRNA genes. The karyotypic relationships correlated well with the molecular phylogeny, and A. semotus had the most highly conserved karyotype among the seven species.

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Section: Introductionmentioning

confidence: 99%

Karyotypic Evolution of Apodemus (Muridae, Rodentia) Inferred from Comparative FISH Analyses

et al. 2004

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“…Comparative chromosome painting, named Zoo-FISH, is a powerful tool for identifying homologous chromosome regions between different species. This approach allows the direct delineation of conserved segments at the molecular level, and provides clues for understanding the process of chromosome evolution (Wienberg et al 1990, Scherthan et al 1994, Wienberg & Stanyon 1995.…”

Section: Introductionmentioning

confidence: 99%

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Matsubara

Nishida‐Umehara

Kuroiwa

et al. 2003

Chromosome Research

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Comparative chromosome painting was applied to the Indian spiny mouse (Mus platythrix) with mouse (M. musculus) chromosome-specific probes for understanding the process of chromosome rearrangements between the two species.The chromosome locations of the 5S and 18S-28S ribosomal RNA genes and the order of the 119 and Tcp-1 genes in the In(17)2 region of the t-complex were also compared.All the painting probes were successfully hybridized to the Indian spiny mouse chromosomes, and a total of 27 segments homologous to mouse chromosomes were identified. The comparative FISH analysis revealed that tandem fusion were major events in the chromosome evolution of the Indian spiny mouse. In addition, other types of chromosome rearrangements, i.e. reciprocal translocations and insertions, were also included.3

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“…Representatives of the Muridae were the first rodents studied by chromosome painting (Scherthan et al, 1994) and today some 29 species from three subfamilies have been investigated (Table 1) using different sets of probes. Generally, murid genomes have been extensively reorganized during evolution.…”

Section: Muridaementioning

confidence: 99%

Chromosomal evolution in Rodentia

et al. 2011

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Rodentia is the most species-rich mammalian order and includes several important laboratory model species. The amount of new information on karyotypic and phylogenetic relations within and among rodent taxa is rapidly increasing, but a synthesis of these data is currently lacking. Here, we have integrated information drawn from conventional banding studies, recent comparative painting investigations and molecular phylogenetic reconstructions of different rodent taxa. This permitted a revision of several ancestral karyotypic reconstructions, and a more accurate depiction of rodent chromosomal evolution.

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Comparative chromosome painting discloses homologous segments in distantly related mammals

Cited by 262 publications

References 46 publications

Karyotypic Evolution of Apodemus (Muridae, Rodentia) Inferred from Comparative FISH Analyses

Karyotypic Evolution of Apodemus (Muridae, Rodentia) Inferred from Comparative FISH Analyses

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Chromosomal evolution in Rodentia

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