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Matsubara, Kazumi; Nishida‐Umehara, Chizuko; Kuroiwa, Asato; Tsuchiya, Koichiro; Matsuda, Yoichi

doi:10.1023/a:1022010116287

Cited by 25 publications

(10 citation statements)

References 18 publications

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“…Our results were similar to those of Matsubara et al [26]: rDNA clusters were present on three chromosomes 5, 8 and 12.…”

Section: Resultssupporting

confidence: 93%

“…Eight of the studied taxa showed a distribution of rDNA clusters that was identical to published data [see Table 1; [26,41,42]]. This included the rare subtelomeric position noted on chromosome 4 in M. m. domesticus [41].…”

Section: Resultssupporting

confidence: 76%

“…Identification of chromosomes was performed by DAPI-banding following the nomenclature of Cowell [29] for the subgenus Mus , Veyrunes et al [22,24] for the subgenera Nannomys and Coelomys , and Matsubara et al [26] for the subgenus Pyromys . At least five metaphases per specimen were analysed.…”

Section: Methodsmentioning

confidence: 99%

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Are ribosomal DNA clusters rearrangement hotspots? A case study in the genus Mus (Rodentia, Muridae)

et al. 2011

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BackgroundRecent advances in comparative genomics have considerably improved our knowledge of the evolution of mammalian karyotype architecture. One of the breakthroughs was the preferential localization of evolutionary breakpoints in regions enriched in repetitive sequences (segmental duplications, telomeres and centromeres). In this context, we investigated the contribution of ribosomal genes to genome reshuffling since they are generally located in pericentromeric or subtelomeric regions, and form repeat clusters on different chromosomes. The target model was the genus Mus which exhibits a high rate of karyotypic change, a large fraction of which involves centromeres.ResultsThe chromosomal distribution of rDNA clusters was determined by in situ hybridization of mouse probes in 19 species. Using a molecular-based reference tree, the phylogenetic distribution of clusters within the genus was reconstructed, and the temporal association between rDNA clusters, breakpoints and centromeres was tested by maximum likelihood analyses. Our results highlighted the following features of rDNA cluster dynamics in the genus Mus: i) rDNA clusters showed extensive diversity in number between species and an almost exclusive pericentromeric location, ii) a strong association between rDNA sites and centromeres was retrieved which may be related to their shared constraint of concerted evolution, iii) 24% of the observed breakpoints mapped near an rDNA cluster, and iv) a substantial rate of rDNA cluster change (insertion, deletion) also occurred in the absence of chromosomal rearrangements.ConclusionsThis study on the dynamics of rDNA clusters within the genus Mus has revealed a strong evolutionary relationship between rDNA clusters and centromeres. Both of these genomic structures coincide with breakpoints in the genus Mus, suggesting that the accumulation of a large number of repeats in the centromeric region may contribute to the high level of chromosome repatterning observed in this group. However, the elevated rate of rDNA change observed in the chromosomally invariant clade indicates that the presence of these sequences is insufficient to lead to genome instability. In agreement with recent studies, these results suggest that additional factors such as modifications of the epigenetic state of DNA may be required to trigger evolutionary plasticity.

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“…Our results were similar to those of Matsubara et al [26]: rDNA clusters were present on three chromosomes 5, 8 and 12.…”

Section: Resultssupporting

confidence: 93%

Section: Resultssupporting

confidence: 76%

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Are ribosomal DNA clusters rearrangement hotspots? A case study in the genus Mus (Rodentia, Muridae)

et al. 2011

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“…The P. sinensis chromosome paints were prepared and provided by Fengtang Yang and Patricia O’Brien, both from the Department of Veterinary Medicine, Cambridge University, UK. Chromosome painting was performed as described previously [12], [21]. One microgram of DNA probe was labeled with biotin-16-dUTP (Roche Diagnostics) using a nick translation kit (Roche Diagnostics).…”

Section: Methodsmentioning

confidence: 99%

The Staurotypus Turtles and Aves Share the Same Origin of Sex Chromosomes but Evolved Different Types of Heterogametic Sex Determination

et al. 2014

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Reptiles have a wide diversity of sex-determining mechanisms and types of sex chromosomes. Turtles exhibit temperature-dependent sex determination and genotypic sex determination, with male heterogametic (XX/XY) and female heterogametic (ZZ/ZW) sex chromosomes. Identification of sex chromosomes in many turtle species and their comparative genomic analysis are of great significance to understand the evolutionary processes of sex determination and sex chromosome differentiation in Testudines. The Mexican giant musk turtle (Staurotypus triporcatus, Kinosternidae, Testudines) and the giant musk turtle (Staurotypus salvinii) have heteromorphic XY sex chromosomes with a low degree of morphological differentiation; however, their origin and linkage group are still unknown. Cross-species chromosome painting with chromosome-specific DNA from Chinese soft-shelled turtle (Pelodiscus sinensis) revealed that the X and Y chromosomes of S. triporcatus have homology with P. sinensis chromosome 6, which corresponds to the chicken Z chromosome. We cloned cDNA fragments of S. triporcatus homologs of 16 chicken Z-linked genes and mapped them to S. triporcatus and S. salvinii chromosomes using fluorescence in situ hybridization. Sixteen genes were localized to the X and Y long arms in the same order in both species. The orders were also almost the same as those of the ostrich (Struthio camelus) Z chromosome, which retains the primitive state of the avian ancestral Z chromosome. These results strongly suggest that the X and Y chromosomes of Staurotypus turtles are at a very early stage of sex chromosome differentiation, and that these chromosomes and the avian ZW chromosomes share the same origin. Nonetheless, the turtles and birds acquired different systems of heterogametic sex determination during their evolution.

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“…This could mean that other negative feedback loops are more important for adaptation than the ERK-MKP1 loop is, and indeed there are several other negative feedback loops. Active ERK1/2 can phosphorylate and thereby feed back upon its upstream regulators MEK, Raf, Sos, and the EGFR itself, and some or all of these loops may help generate the canonical pulse of ERK activity (Brunet et al, 1994;Fritsche-Guenther et al, 2011;Li et al, 2008;Matsuda et al, 1993;Shin et al, 2009). Or it could be that some other type of motif provides the adaptation.…”

Section: Negative Feedbackmentioning

confidence: 99%

Perfect and Near-Perfect Adaptation in Cell Signaling

2016

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Adaptation is an important basic feature of cellular regulation. Previous theoretical work has identified three types of circuits-negative feedback loops, incoherent feedforward systems, and state-dependent inactivation systems-that can achieve perfect or near-perfect adaptation. Recent work has added another strategy, termed antithetic integral feedback, to the list of motifs capable of robust perfect adaptation. Here, we discuss the properties, limitations, and biological relevance of each of these circuits.

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Cited by 25 publications

References 18 publications

Are ribosomal DNA clusters rearrangement hotspots? A case study in the genus Mus (Rodentia, Muridae)

Are ribosomal DNA clusters rearrangement hotspots? A case study in the genus Mus (Rodentia, Muridae)

The Staurotypus Turtles and Aves Share the Same Origin of Sex Chromosomes but Evolved Different Types of Heterogametic Sex Determination

Perfect and Near-Perfect Adaptation in Cell Signaling

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