Comparative cardiovascular effects of four fishery anesthetics in spinally transected rainbow trout, oncorhynchus mykiss

Fredricks, Kim T.; Gingerich, William H.; Fater, Dennis C.

doi:10.1016/0742-8413(93)90021-c

Cited by 31 publications

(23 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Metomidate, the active compound in AquaCalm, has a more hypnotic effect with potential cortisol suppressing properties by blockage of release from the inter-renal cells (Olsen et al, 1995;Small, 2003). This drug causes drastic reduction in blood pressure in rainbow trout (Fredricks et al, 1993). Of special relevance are earlier findings that there was no cortisol response to handling stress in metomidate sedated Atlantic salmon (Olsen et al, 1995).…”

Section: Anestheticsmentioning

confidence: 78%

The effect of anesthetics on carotenoid pigmentation and behavior in Arctic char (Salvelinus alpinus)

Bäckström

Heynen

Brännäs

et al. 2015

Journal of Veterinary Behavior

View full text Add to dashboard Cite

Status of individual animals is often shown in pigmentation. For instance, stress responsiveness is associated with melanin-based pigmentation in vertebrates in general. This pattern is evident in Atlantic salmon (Salmo salar) and rainbow trout (Onchorhynchus mykiss) with melanin-based spots indicating stress coping style. Arctic charr (Salvelinus alpinus) differ from other salmonids in pigmentation but have an association between carotenoid-based pigmentation and stress coping style. These pigmentation differences could be used as a fast and simple tool for improving breeding programs. However, the procedure for photographing individuals is stressful. Therefore we wanted to investigate if three common inhalation anesthetics could be used to reduce the stress involved in the procedure compared to a no-anesthetics group. Behavior was also monitored during the anaesthetization. All three anesthetics (AquaCalm, Benzocaine, and MS-222) differed in pigmentation compared to the no-anesthetics group, by having a higher number of spots. In the anesthetic treatments as well as the no-anesthetics group the fish had elevated plasma cortisol levels. In fact the no-anesthetics group had higher cortisol than treated fish. This was probably procedural differences such as time affecting the stress response. Further, in a longterm experiment all fish survived and had similar condition factors one week after photographing as before. Therefore the method for photographing Arctic charr is deemed safe and could be used for as a tool for estimating stress coping style, but careful planning is needed for experiments using it.

show abstract

Section: Anestheticsmentioning

confidence: 78%

The effect of anesthetics on carotenoid pigmentation and behavior in Arctic char (Salvelinus alpinus)

Bäckström

Heynen

Brännäs

et al. 2015

Journal of Veterinary Behavior

View full text Add to dashboard Cite

show abstract

“…The following increase in plasma TA during stage 4 anaesthesia could be explained by increased endogenous ammonia production due to adenylate deamination in hypoxemic muscle (Wood 1993) and possibly also shuttling of ammonia from intracellular compartments in combination with reduced ammonia excretion over the gills due to reduced ventilation and circulation. Reduced oxygen consumption and ammo-nia excretion is described in teleosts during effective anaesthesia with several anaesthetics (McFarland 1959;Ferreira et al 1984), and respiratory and cardivasculatory depression are common side-effects reported for most anaesthetics (Houston et al 1971;Soivo et al 1977;Iwama et al 1989;Mattson and Riple 1989;Fredricks et al 1993;Ryan et al 1993). Increased blood Pco levels and acidosis are reported in fish as a result of respiratory depression during anaesthesia, also for metomidate (Soivo et al 1977;Iwama et al 1989).…”

Section: Discussionmentioning

confidence: 93%

Effects of metomidate anaesthesia or transfer to pur sea water on plasma parameters in ammonia-exposed Atlantic salmon (Salmo salar L) in sea water

Knoph

1995

Fish Physiol Biochem

View full text Add to dashboard Cite

Atlantic salmon (Salmo salar L) postsmolts weighing 150 ± 53 g were exposed to 14-15 mg l(-1) TA-N (total ammonia-N) in sea water in 1 m(3) tanks for 24h. Blood samples were then taken A) immediately after the fish were netted from the exposure tanks and stunned by a blow to the head; B) 2-20 min after the fish were transferred to 15 l of an anaesthetic solution of metomidate in "ammonia-free" sea water; or C) 2-20 min after the fish were transferred to 15 l of "ammonia-free" sea water. Plasma TA-N level was 18% lower in the anaesthetised fish compared to in the fish sampled directly from the exposure tanks (p ≤ 0.05), and accordingly 16% lower in the fish transferred to pure sea water although this difference was not significant (p = 0.07). Plasma glucose level was higher in the fish transferred to pure sea water than in the fish receiving the two other treatments (p ≤ 0.05), but plasma urea, osmolality, Na(+, Cl-, Ca2+ or Mg2+) levels did not vary significantly between the different treatments. Plasma TA-N level increased with time in the fish in the metomidate solution (p ≤ 0.02).

show abstract

“…However, 2-phenoxyethanol has poor analgesic properties, a narrow margin of safety, is an irritant to mucous membranes, decreases blood pH, increases adrenaline and glucose levels and acts as an immunosuppressant (Fredricks et al, 1993). Furthermore, a sustained and regular exposure to 2-phenoxyethanol has been reported to cause a neuropsychological syndrome in some handlers (Hseu et al, 1998).…”

Section: Discussionmentioning

confidence: 94%

“…This drug has a short anesthesia induction time, rapid recovery and low price (Weyl et al, 1996). However, adverse effects such as decreased heart rate and low blood pressure (Fredricks et al, 1993), or respiratory depression (Ortuño et al, 2002), have been described in fish.…”

Section: Introductionmentioning

confidence: 98%

The efficacy and effect of repeated exposure to 2-phenoxyethanol, clove oil and tricaine methanesulphonate as anesthetic agents on juvenile Angelfish (Pterophyllum scalare)

et al. 2014

View full text Add to dashboard Cite

Comparative cardiovascular effects of four fishery anesthetics in spinally transected rainbow trout, oncorhynchus mykiss

Cited by 31 publications

References 25 publications

The effect of anesthetics on carotenoid pigmentation and behavior in Arctic char (Salvelinus alpinus)

The effect of anesthetics on carotenoid pigmentation and behavior in Arctic char (Salvelinus alpinus)

Effects of metomidate anaesthesia or transfer to pur sea water on plasma parameters in ammonia-exposed Atlantic salmon (Salmo salar L) in sea water

The efficacy and effect of repeated exposure to 2-phenoxyethanol, clove oil and tricaine methanesulphonate as anesthetic agents on juvenile Angelfish (Pterophyllum scalare)

Contact Info

Product

Resources

About