“…In some invasive fungal diseases, such as aspergillosis, cryptococcosis, and histoplasmosis, the detection of circulating antigens is a useful approach to immunodiagnosis (9,10,15,19,36) and, in some cases, may also help the clinician to evaluate the clinical response to antifungal therapy. Some tests have been used to detect gp43 circulating antigen with partial success in PCM (12,13,14,16,17,21,22,30).…”