2012
DOI: 10.1016/j.memsci.2012.02.005
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Comparative application of pressure- and electrically-driven membrane processes for isolation of bioactive peptides from soy protein hydrolysate

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Cited by 43 publications
(26 citation statements)
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“…Besides, the fractionation process makes it possible to control the molecular-weight distribution of the hydrolysates and to concentrate the desired bioactive or functional peptides (Akin et al, 2012). For that purpose, pressure-driven membrane techniques (e.g., ultrafiltration) are commonly used since they can easily be scaled-up (Langevin et al, 2012). Although most of the studies reported in the literature utilize polymeric membranes (Chabeaud et al, 2009;Jiang et al, 2010;Hwang et al, 2016), ceramic membranes are preferred at industrial scale due to their high chemical resistance, wider operational limits of pH and temperature, as well as extended operational lifetime (Lin et al, 2011;Espejo-Carpio et al, 2014b).…”
Section: Removing Bitternessmentioning
confidence: 99%
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“…Besides, the fractionation process makes it possible to control the molecular-weight distribution of the hydrolysates and to concentrate the desired bioactive or functional peptides (Akin et al, 2012). For that purpose, pressure-driven membrane techniques (e.g., ultrafiltration) are commonly used since they can easily be scaled-up (Langevin et al, 2012). Although most of the studies reported in the literature utilize polymeric membranes (Chabeaud et al, 2009;Jiang et al, 2010;Hwang et al, 2016), ceramic membranes are preferred at industrial scale due to their high chemical resistance, wider operational limits of pH and temperature, as well as extended operational lifetime (Lin et al, 2011;Espejo-Carpio et al, 2014b).…”
Section: Removing Bitternessmentioning
confidence: 99%
“…As an example, target bioactive peptides with similar molecular weight, which cannot be separated by pressure-driven membranes, have been concentrated by electrodialysis with ultrafiltration membranes (Doyen et al, 2014;He et al, 2016). Furthermore, sequential ultrafiltration and nanofiltration stages have also been tested in order to obtain even more concentrated peptide fractions with a reduced salt content (Langevin et al, 2012;Ranamukhaarachchi et al, 2013). In contrast, fractionation techniques are seldom applied to improve functional properties of protein hydrolysates.…”
Section: Removing Bitternessmentioning
confidence: 99%
“…The combination of membrane processes (UF and NF) is often used in the separation of peptides [ 100 , 126 , 127 ]. To improve the yield and selectivity of the peptide separation, other driving forces have been used in the membrane process, including electrical potential difference (electrodialysis and electrophoresis) and the combination of electrical potential gradients and pressure (electronanofiltration and electrofiltration) [ 128 , 129 , 130 , 131 , 132 ].…”
Section: Recovery and Purification Processmentioning
confidence: 99%
“…The combination of bioinformatics and chemometrics tools speeds up the screening of various peptide sources with high levels of biological activity and optimises the process of isolating (selected substrates) and identifying peptides in food products. The process of identifying and isolating peptides in a laboratory and in industrial applications is overviewed in Table 2 [Carrasco-Castilla et al , Korhonen and Pihlanto 2006, 2007, Langevin et al 2012, Minkiewicz and Dziuba 2009.…”
Section: Strategy For Isolating and Analysing Bioactive Peptidesmentioning
confidence: 99%