The article presents the results of evaluation studies on the elemental composition of Anthemis trotzkiana Claus plants growing in the Aktobe region in Western Kazakhstan. All selected samples from three populations of a rare plant species for chemical composition were examined by atomic absorption spectroscopy. Evaluation studies of the elemental composition of the vegetative organs of A. trotzkiana have shown that extracts obtained from leaves, roots, and stems of plants can be a promising source of macro- and microelements for pharmacopoeial purposes. Endemism of the species A. trotzkiana, distributed locally in the regions of Western Kazakhstan, requires measures for the rational use of this species.