A comparative radio-frequency (RF) and crosstalk analysis is performed on carbon nanointerconnects based on an efficient π-type equivalent single-conductor model of bundled multiwall carbon nanotubes (MWCNTs) and stacked multilayer graphene nanoribbons (MLGNRs). Simulation results are extracted using HSPICE for global-level nanointerconnects at the 14-nm node. RF performance is evaluated in terms of skin depth and a 3-dB bandwidth, while crosstalk performance is analysed in terms of crosstalk-induced delay and average power consumption. The skin-depth results indicate significant improvements in skin-depth degradation at higher frequencies for AsF 5-doped zigzag MLGNRs compared with that of Cu, nanotubes and MWCNTs. The transfer gain results explicitly demonstrate that AsF 5-doped MLGNRs exhibit excellent RF behaviour, showing 10-and 20-fold improvements over MWCNTs and copper (Cu), respectively. Further, the 3-dB bandwidth calculations for AsF 5-doped MLGNRs suggest 18.6-and 9.7-fold enhancement compared with Cu and MWCNTs at 1000 μm. Significant reductions are obtained in crosstalk-induced out-of-phase delays for AsF 5-doped MLGNRs-their delay values were 84.7% and 60.24% less than those for Cu and MWCNTs. Further, AsF 5-doped MLGNRs present the most optimal energy-delay product results, with values representing 98.6% and 99.6% improvements over their Cu and MWCNT counterparts at a global length of 1000 µm. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.