Comparative Analysis of Risk Management Strategies for Additive Manufacturing Supply Chains

Altubaishe, Bandar; Clarke, Jahlani; McWilliams, Christina; Desai, Salil

doi:10.3844/ajassp.2019.273.282

Cited by 7 publications

(7 citation statements)

References 27 publications

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“…A 3D printer builds an object by depositing the desired material layer-by-layer. The biomedical device industry has seen a rapid rise of 3D printing technologies in tissue engineering implants in recent years [ 153 , 154 , 155 , 156 , 157 , 158 , 159 , 160 , 161 , 162 , 163 , 164 ]. In 2019, Johnson et al fabricated the first MN master using a commercial 3D printer [ 60 ].…”

Section: Mn Manufacturing Methodsmentioning

confidence: 99%

A Comprehensive Review of Microneedles: Types, Materials, Processes, Characterizations and Applications

2021

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Drug delivery through the skin offers many advantages such as avoidance of hepatic first-pass metabolism, maintenance of steady plasma concentration, safety, and compliance over oral or parenteral pathways. However, the biggest challenge for transdermal delivery is that only a limited number of potent drugs with ideal physicochemical properties can passively diffuse and intercellularly permeate through skin barriers and achieve therapeutic concentration by this route. Significant efforts have been made toward the development of approaches to enhance transdermal permeation of the drugs. Among them, microneedles represent one of the microscale physical enhancement methods that greatly expand the spectrum of drugs for transdermal and intradermal delivery. Microneedles typically measure 0.1–1 mm in length. In this review, microneedle materials, fabrication routes, characterization techniques, and applications for transdermal delivery are discussed. A variety of materials such as silicon, stainless steel, and polymers have been used to fabricate solid, coated, hollow, or dissolvable microneedles. Their implications for transdermal drug delivery have been discussed extensively. However, there remain challenges with sustained delivery, efficacy, cost-effective fabrication, and large-scale manufacturing. This review discusses different modes of characterization and the gaps in manufacturing technologies associated with microneedles. This review also discusses their potential impact on drug delivery, vaccine delivery, disease diagnostic, and cosmetics applications.

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Section: Mn Manufacturing Methodsmentioning

confidence: 99%

A Comprehensive Review of Microneedles: Types, Materials, Processes, Characterizations and Applications

2021

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“…Table 5 shows the risk priority numbers for each sub-criterion for all suppliers calculated using the traditional FMEA model as [31]. As can be seen in Table 5, supplier B has the lowest total (40) and average (6.7) for the RPN among all suppliers. Thus, based on the traditional FMEA model, supplier B is the preferred choice of supplier for the corporation due to its lowest risk potential.…”

Section: Contrasting Supplier Selection Methodologiesmentioning

confidence: 99%

“…The second aspect involves determining the evaluation methods to be used to compare different suppliers [39]. The criteria considered in supplier evaluation are industry-specific [40]. In other words, the selection of criteria can be adapted based on the requirements of each industry with data acquisition and augmentation using edge-based sensors.…”

Section: The Literature Reviewmentioning

confidence: 99%

Multicriteria Decision Making in Supply Chain Management Using FMEA and Hybrid AHP-PROMETHEE Algorithms

Altubaishe

Desai

2023

Sensors

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In today’s global environment, supplier selection is one of the critical strategic decisions made by supply chain management. The supplier selection process involves the evaluation of suppliers based on several criteria, including their core capabilities, price offerings, lead times, geographical proximity, data collection sensor networks, and associated risks. The ubiquitous presence of internet of things (IoT) sensors at different levels of supply chains can result in risks that cascade to the upstream end of the supply chain, making it imperative to implement a systematic supplier selection methodology. This research proposes a combinatorial approach for risk assessment in supplier selection using the failure mode effect analysis (FMEA) with hybrid analytic hierarchy process (AHP) and the preference ranking organization method for enrichment evaluation (PROMETHEE). The FMEA is used to identify the failure modes based on a set of supplier criteria. The AHP is implemented to determine the global weights for each criterion, and PROMETHEE is used to prioritize the optimal supplier based on the lowest supply chain risk. The integration of multicriteria decision making (MCDM) methods overcomes the shortcomings of the traditional FMEA and enhances the precision of prioritizing the risk priority numbers (RPN). A case study is presented to validate the combinatorial model. The outcomes indicate that suppliers were evaluated more effectively based on company chosen criteria to select a low-risk supplier over the traditional FMEA approach. This research establishes a foundation for the application of multicriteria decision-making methodology for unbiased prioritization of critical supplier selection criteria and evaluation of different supply chain suppliers.

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“…Lately, additive manufacturing, more commonly known as 3D printing, has rapidly been gaining attention as a means of manufacturing microneedles and molds [192]. In fact, the biomedical device industry has witnessed a swift adoption of 3D printing technologies for tissue engineering implants in recent years [256][257][258][259][260][261].…”

Section: Additive Manufacturingmentioning

confidence: 99%

Microneedles Patch: Design, Fabrication and Applications

Oliveira,

Teixeira,

Oliveira

et al. 2024

Preprint

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The delivery of therapeutical molecules through the skin, particularly to its deeper layers is impaired due to the stratum corneum layer, which acts as barrier to foreign substances. Thus, for the past years, scientists have focused on the development of more efficient methods to deliver molecules to skin distinct layers. Microneedles, as a new class of biomedical devices, consists on an array of microscale needles. This particular biomedical device had been drawing attention due to their ability to breach the stratum corneum, forming micro-conduits to facilitate the passage of therapeutical molecules. The microneedle device has several advantages over conventional methods, such as better medication adherence, easiness and painless self-administration. Moreover, it is possible to deliver the molecules swiftly or over time. Microneedles can vary in shape, size and composition. The design process of a microneedle device must take in account several factors, like the location delivery, the material and manufacturing process. Microneedles have been used in a large number of fields from drug and vaccine application, cosmetics, therapy, diagnosis, tissue engineering, sample extraction, cancer research, wound healing, among others.

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Comparative Analysis of Risk Management Strategies for Additive Manufacturing Supply Chains

Cited by 7 publications

References 27 publications

A Comprehensive Review of Microneedles: Types, Materials, Processes, Characterizations and Applications

A Comprehensive Review of Microneedles: Types, Materials, Processes, Characterizations and Applications

Multicriteria Decision Making in Supply Chain Management Using FMEA and Hybrid AHP-PROMETHEE Algorithms

Microneedles Patch: Design, Fabrication and Applications

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