Comparative Analysis of Prostate Volume as a Predictor of Outcome in Prostate Artery Embolization

Bagla, Sandeep; Smirniotopoulos, John; Orlando, J.; Breda, Arina van; Vadlamudi, Venu

doi:10.1016/j.jvir.2015.08.018

Cited by 68 publications

(55 citation statements)

References 16 publications

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“… Note: Data from Isaacson et al,9 Bagla et al,10 Li et al,11 and Wang et al12 Abbreviations: BPH, benign prostatic hyperplasia; CI, confidence interval; IIEF-5, International Index of Erectile Function; IPSS, International Prostate Symptom Score; MD, mean difference; PAE, prostate artery embolization; PSA, prostate-specific antigen; PV, prostate volume; PVR, postvoid residual; Q max , peak urinary flow rate; QoL, quality of life.…”

Section: Figurementioning

confidence: 99%

Efficacy and safety of prostate artery embolization on lower urinary tract symptoms related to benign prostatic hyperplasia: a systematic review and meta-analysis

Wang

Zong

Zhang

2016

CIA

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BackgroundProstate artery embolization (PAE) is emerging and is a promising minimally invasive therapy that improves lower urinary tract symptoms (LUTS) related to benign prostatic hyperplasia (BPH). The purpose of this article was to evaluate the efficacy and safety of PAE on LUTS related to BPH.Materials and methodsA literature review was performed to identify all published articles of PAE for BPH. The sources included MEDLINE, EMBASE and Cochrane Library from 1980 to 2016. A systematic review and meta-analysis was conducted. The outcome measurements were combined by calculating the mean difference with 95% confidence interval. Statistical analysis was carried out using Review Manager 5.3.0.ResultsTwelve studies involving 840 participants were included. Compared with baseline, the International Index of Erectile Function (IIEF-5; International Prostate Symptom Score) scores, the quality of life scores, peak urinary flow rate (Qmax) and postvoid residual volume all had significant improvements during the 24-month follow-up (all P<0.00001). Both prostate volume (PV) and prostate-specific antigen had significant decrease during the 12-month follow-up (P<0.00001 and P=0.005, respectively), except postoperative 24 months (P=0.47 and P=0.32, respectively). The IIEF-5 short form scores had significant increase at postoperative 6 months (P=0.002) and 12 months (P<0.0001), except postoperative 1 month (P=0.23) and 24 months (P=0.21). For large volume (PV ≥80 mL) BPH, the results were similar. There were no life-threatening complications.ConclusionPAE is an effective, safe and well-tolerable treatment for LUTS related to BPH, including large volume (PV ≥80 mL) BPH, with a good short-term follow-up. Studies with large number of cases and longer follow-up time are needed to validate our results.

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Section: Figurementioning

confidence: 99%

Efficacy and safety of prostate artery embolization on lower urinary tract symptoms related to benign prostatic hyperplasia: a systematic review and meta-analysis

Wang

Zong

Zhang

2016

CIA

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“…In a wide systematic review by Kuang et al (18), all data by relative recent studies have been compared to demonstrate a significant improvement of Qmax, IPSS and QoL associated with reduced PV and PVR in a maximum FU of 24 months. Consistent results emerge also from large prostates trials: Bagla et al (20) have tested PAE effectiveness in three group with increasing prostate size (mean volumes: 37.5, 65.7, 139.4 cm 2 ) during a maximum FU term of 6 months and have demonstrated high and stable rate of clinical success with significant QoL improvement in small prostates as in the larger ones.…”

Section: Resultsmentioning

confidence: 52%

“…All studies included only symptomatic patients presenting moderate or severe LUTS (12,(20)(21)(22)(23)(24). Some of them (12,21,23,24), also specified the required grade of LUTS in terms of IPSS: Li defined a threshold score of 12 (23), while Bilhim, Pisco and Wang demanded an IPSS higher than 18, therefore involving only patients with severe LUTS (12,21,24).…”

Section: Indicationsmentioning

confidence: 99%

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State of the art of prostatic arterial embolization for benign prostatic hyperplasia

et al. 2018

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Prostatectomy via open surgery or transurethral resection of the prostate (TURP) is the standard treatment for benign prostatic hyperplasia (BPH). Several patients present contraindication for standard approach, individuals older than 60 years with urinary tract infection, strictures, post-operative pain, incontinence or urinary retention, sexual dysfunction, and blood loss are not good candidates for surgery. Prostatic artery embolization (PAE) is emerging as a viable method for patients unsuitable for surgery. In this article, we report results about technical and clinical success and safety of the procedure to define the current status.

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“…sPVA size did not affect the relapse rate after 12 months [22]. Prostate volume does not seem to have an effect on the outcome of PAE since there is no statistically significant differences for IPSS, QoL, and IIEF 6 months after treatment between the groups PV < 50 ml, PV 50 -80 ml and PV > 80 ml [23]. In contrast, a younger age (≤ 65 years) and the bilateral embolization of the prostate arteries seem to be associated with improved clinical success [20].…”

Section: Study Resultsmentioning

confidence: 79%

Prostate Artery Embolization: Indication, Technique and Clinical Results

Teichgräber

Aschenbach

Diamantis

et al. 2018

Fortschr Röntgenstr

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ABSTR AC T Background Prostate artery embolization (PAE) is a new embolization therapy to treat benign prostate syndrome (BPS). Materials and MethodsThis review article presents the rationale and impact mechanism of PAE, criteria for patient selection, and discusses the anatomy of prostate arteries. The study results are seen in the context of complications and clinical partners.Results Important preconditions for successful prostate artery embolization are a strict indication, precise knowledge of the anatomy of the pelvic arteries and advanced interventional-radiological skills. Several studies showed that urological parameters after prostate artery embolization improve at a similar level as for established post-surgical treatments. At the same time, it could be proven that prostate artery embolization has no impact on erectile function and is associated with a relatively low complication rate.Conclusion PAE is increasingly developing to an alternative for the established surgical treatments in BPS patients. Key Points▪ PAE is a new embolization method for treating BPS and represents an alternative to classic urological surgical procedure such as TURP. ▪ Due to the low caliber of the prostate artery (0.5 -2 mm), the presence of anatomical variations, and the arteriosclerosis seen in most older men, PAE is a technically challenging embolization method. ▪ In patients with a high postoperative bleeding risk in classic urological surgical treatment concepts, PAE is a very gentle alternative method. Citation

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Comparative Analysis of Prostate Volume as a Predictor of Outcome in Prostate Artery Embolization

Cited by 68 publications

References 16 publications

Efficacy and safety of prostate artery embolization on lower urinary tract symptoms related to benign prostatic hyperplasia: a systematic review and meta-analysis

Efficacy and safety of prostate artery embolization on lower urinary tract symptoms related to benign prostatic hyperplasia: a systematic review and meta-analysis

State of the art of prostatic arterial embolization for benign prostatic hyperplasia

Prostate Artery Embolization: Indication, Technique and Clinical Results

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