Comparative analysis of prebiotic effects of seaweed polysaccharides laminaran, porphyran, and ulvan using in vitro human fecal fermentation

Seong, Hyunbin; Bae, Jae Hoon; Seo, Ji Sun; Kim, Seul-Ah; Kim, Tae-Jip; Han, Nam Soo

doi:10.1016/j.jff.2019.04.014

Cited by 76 publications

(56 citation statements)

References 53 publications

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“…Nevertheless, the slow fermentation of OP powders could be an advantage in terms of health benefits, e.g. to avoid the production of gases that can result in discomfort, such as bloating and flatulence, and will also allow the production of SCFAs throughout the colon preventing colon cancer, which mainly occurs in the distal colon (Seong et al, 2019).…”

Section: Changes In Faecal Microbial Communities During In Vitro Fermmentioning

confidence: 99%

Prebiotic effects of olive pomace powders in the gut: In vitro evaluation of the inhibition of adhesion of pathogens, prebiotic and antioxidant effects

et al. 2021

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Olive pomace is a biowaste rich in polyphenols and insoluble dietary fibre with high potential to develop new value chains towards a sustainable and circular bioeconomy. Regarding gut health, olive pomace phenolics and insoluble dietary fibre (after possible fermentation) could act as antioxidants, antimicrobial and prebiotic agents. These potential beneficial effects on the gut were analysed for two powders from olive pomace: liquid-enriched powder (LOPP)-mostly source of phenolics-and pulp-enriched powder (POPP)-main source of insoluble dietary fibre. LOPP and POPP were subjected to an in vitro simulated gastrointestinal digestion followed by in vitro faecal fermentation. The undigested fraction retained in the colon was analysed regarding its potential antioxidant, antimicrobial and prebiotic effects. LOPP and POPP did not impact the gut microbiota diversity negatively, showing a similar ratio of Firmicutes/Bacteroidetes compared to a positive control (FOS). LOPP exhibit a positive (similar to FOS) effect on the Prevotella spp./Bacteroides spp. ratio. Both powders promoted more the production of short-chain fatty acids (mainly acetate > butyrate > propionate) than FOS and showed also significant total phenolic content and oxygen radical absorbance capacity during faecal fermentation until 48 h. Besides that, these powders showed mucin-adhesion inhibition ability against pathogens, principally POPP against Bacillus cereus (22.03 ± 2.45%) and Listeria monocytogenes (20.01 ± 1.93%). This study demonstrates that olive pomace powders have prebiotic effects on microbiota, including the stimulation of short-chain fatty acids production, potential antioxidant and antimicrobial activity which could improve the human gut health.

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Section: Changes In Faecal Microbial Communities During In Vitro Fermmentioning

confidence: 99%

Prebiotic effects of olive pomace powders in the gut: In vitro evaluation of the inhibition of adhesion of pathogens, prebiotic and antioxidant effects

et al. 2021

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“…Kong et al [82] performed an in vitro assay using Enteromorpha with a high content of ulvans, but there were no noticeable variations in the populations of Enterococcus, Lactobacillus and Bifidobacterium compared with controls. In contrast, in a recent in vitro faecal fermentation analysis, ulvans stimulated the growth of Bifidobacterium and Lactobacillus populations and promoted the production of SCFA, such as lactic and acetic acids [42]. In a previous study by Ren et al [114], both whole Enteromorpha and polysaccharides extracted from Enteromorpha improved inflammation associated with loperamide-induced constipation in mice.…”

Section: Polysaccharides From Green Seaweedsmentioning

confidence: 88%

“…It was previously shown that variations in the chemical structure of a prebiotic can impact its selective fermentation by bacteria [41]. For this reason, there were published large works regarding the investigation of the potential prebiotic effect of single polysaccharides, often contained in seaweeds, but employing pure standards [42][43][44]. However, it should be considered that seaweeds contain other components than also can affect GM.…”

Section: Polysaccharides From Marine Seaweedsmentioning

confidence: 99%

“…Being much less degradable by enzymes from the human upper gastrointestinal tract than their terrestrial plant counterparts, polysaccharides from marine algae reach a greater proportion in the descending colon. For this reason, some authors [42,74] have found that polysaccharides from marine algae, such as alginate, agarose oligosaccharides and κ-carrageenan oligosaccharides, have a higher prebiotic activity than FOS in vitro. Specifically, sulphated polysaccharides from marine algae show anticoagulant, antiviral, antitumor, anti-inflammatory, antibacterial, immunological, antioxidant and many other biological and physiological activities [8,75].…”

Section: Effects Of Seaweed Polysaccharides On Human Healthmentioning

confidence: 99%

“…In other research, laminarin has been shown to promote an immune response [98], and could be useful for inhibiting the production of putrefactive substances from undigested proteins [100]. In vitro batch fermentation of laminarin for 24 h promoted an increase in Bifidobacterium and Bacteroides, and propionate and butyrate production [42]. Contradicting results by other researchers indicated that laminarin was not selectively fermented by Lactobacillus and Bifidobacterium, but could modify the composition, secretion and metabolism of the jejunal, ileal, caecal and colonic mucosa to protect against bacterial translocation [32].…”

Section: Polysaccharides From Brown Seaweedsmentioning

confidence: 99%

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Potential Use of Marine Seaweeds as Prebiotics: A Review

et al. 2020

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Human gut microbiota plays an important role in several metabolic processes and human diseases. Various dietary factors, including complex carbohydrates, such as polysaccharides, provide abundant nutrients and substrates for microbial metabolism in the gut, affecting the members and their functionality. Nowadays, the main sources of complex carbohydrates destined for human consumption are terrestrial plants. However, fresh water is an increasingly scarce commodity and world agricultural productivity is in a persistent decline, thus demanding the exploration of other sources of complex carbohydrates. As an interesting option, marine seaweeds show rapid growth and do not require arable land, fresh water or fertilizers. The present review offers an objective perspective of the current knowledge surrounding the impacts of seaweeds and their derived polysaccharides on the human microbiome and the profound need for more in-depth investigations into this topic. Animal experiments and in vitro colonic-simulating trials investigating the effects of seaweed ingestion on human gut microbiota are discussed.

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