Comparative analysis of analgesic activities of dermorphin, [DPro6]-dermorphin, and their C-terminal tripeptides

Guzevatykh, L. S.; Воронина, Т. А.; Emel'yanova, T. G.; Андреева, Л. А.; Gromovykh, P. S.; Myasoedov, N. F.; Seredenin, S. B.

doi:10.1134/s106235900705010x

Cited by 1 publication

(2 citation statements)

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“…Utilizing data on the processes occurring on the surface of the catalyst enables the optimization of the conditions of solid‐and liquid‐phase reactions, and demonstrates that there are hidden links between the various methods of labelling organic compounds using isotopic exchange. The use of liquid‐phase methods, solvent‐free catalyst systems, and tritiated water isotopic exchange makes it possible to introduce tritium into practically any biologically active compound 63–73 …”

Section: Discussionmentioning

confidence: 99%

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The efficiency of solvent‐free catalyst systems in the synthesis of tritium‐labelled biologically active compounds

Shevchenko

Nagaev

Myasoedov

2010

Labelled Comp Radiopharmac

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Modern theories about the processes that take place inside solvent‐free catalyst systems are considered and the various factors that have an effect on the successful introduction of tritium into organic compounds are summarized. Obtaining labelled compounds using solvent‐free catalyst systems, liquid‐phase methods, and isotopic exchange with tritiated water are all regarded as various manifestations of the same set of occurrences in the presence of tritium, a substrate and a catalyst. The use of various isotopic exchange methods has made possible the introduction of tritium into practically any type of biologically active compound. This will enable scientists to carry out more detailed studies of the processes inside living organisms. Copyright © 2010 John Wiley & Sons, Ltd.

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Section: Discussionmentioning

confidence: 99%

“…The use of liquid‐phase methods, solvent‐free catalyst systems, and tritiated water isotopic exchange makes it possible to introduce tritium into practically any biologically active compound 63–73…”

Section: Discussionmentioning

confidence: 99%