Comparação de métodos de avaliação nutricional empregados no acompanhamento de pacientes submetidos a transplante de células-tronco hematopoéticas alogênico

Sommacal, Heloisa Martins; Jochims, Ana Maria Keller; Schuch, Ilaine; Silla, Lúcia Mariano da Rocha

doi:10.1590/s1516-84842010005000012

Cited by 7 publications

(8 citation statements)

References 15 publications

(31 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The mean length of hospitalization observed in this study was similar to those previously reported by Bechard et al (38 days) 16 and Sommacal et al (39 days). 17 The median time to engraftment in the current study was also similar to that observed by Bechard et al (20 days).…”

Section: Discussionsupporting

confidence: 91%

Nutritional status of patients submitted to transplantation of allogeneic hematopoietic stem cells: a retrospective study

Ferreira

Guerra

Baluz

et al. 2014

Revista Brasileira de Hematologia e Hemoterapia

View full text Add to dashboard Cite

ObjectiveThis study aimed to describe and compare the nutritional status of adult patients submitted to allogeneic hematopoietic stem cell transplantation at two different time points (admission and discharge).MethodsA retrospective, descriptive and quantitative study was performed based on clinical, laboratory and nutritional data obtained from medical records of adult patients of both genders submitted to allogeneic hematopoietic stem cell transplantation in a bone marrow transplantation reference center in Rio de Janeiro in the period from 2010 to 2013. Statistical analysis was performed using the SPSS software (version 22.0).ResultsSixty-four patients were evaluated. The mean age was 42.1 ± 3.2 years and the most prevalent disease was acute myeloid leukemia (39%). There was a high prevalence of gastrointestinal symptoms including nausea (100%), vomiting (97%) and mucositis (93%). Between admission and discharge there was a significant decrease in the median weight (−2.5 kg; 71.5 vs. 68.75 kg; p-value < 0.001), body mass index (−0.9 kg/m2; 24.8 vs. 24.4 kg/m2; p-value < 0.001), and serum albumin levels (−0.2 g/dL; 3.7 vs. 3.6 g/dL; p-value = 0.024). The survival time after hematopoietic stem cell transplantation correlated negatively with C-reactive protein at discharge (CC = −0.72; p-value < 0.001) and positively with serum albumin levels (CC = 0.56; p-value = 0.004) and with high total protein level at discharge (CC = 0.53; p-value = 0.006).ConclusionOur results suggest that patients submitted to allogeneic hematopoietic stem cell transplantation have compromised nutritional status during the hospital stay for transplantation.

show abstract

Section: Discussionsupporting

confidence: 91%

Nutritional status of patients submitted to transplantation of allogeneic hematopoietic stem cells: a retrospective study

Ferreira

Guerra

Baluz

et al. 2014

Revista Brasileira de Hematologia e Hemoterapia

View full text Add to dashboard Cite

show abstract

“…In spite of the low food consumption of the patients who underwent allogeneic HSCT, the average length of the hospital stay (30 days) was similar or lower to the results found by Ferreira et al 9 (36 days), Garófolo 23 (37 days), Sommacal 22 (39 days) and So et al 4 (31 days). The time lapsed from transplantation to engraftment (17 days) was longer than the time reported by So et al 4 (13 days) and close to that of Ferreira et al 9 (18 days).…”

Section: Discussionsupporting

confidence: 81%

“…On comparing nutritional evaluation methods in patients who underwent allogeneic HSCT, Sommacal et al 22 stated that the percentage of weight loss associated with fortnightly assessed anthropometric measures, such as arm circumference and triceps skinfold thickness, are adequate methods for the nutritional follow-up of patients. However, during hospitalization, an imbalance of electrolytes and fluids in patients might occur, likely leading to a positive hydric balance, which might affect the anthropometric evaluation and conceal the real weight of the patient.…”

Section: Discussionmentioning

confidence: 99%

Caloric and protein intake in different periods of hospitalization of patients undergoing hematopoietic stem cell transplantation

Garios

Oliveira

Aguiar

et al. 2018

Hematology, Transfusion and Cell Therapy

View full text Add to dashboard Cite

ObjectiveTo evaluate the nutritional status and caloric and protein intake during the hospitalization of patients undergoing hematopoietic stem cell transplantation.MethodsA retrospective study was performed based on clinical and nutritional data of patients undergoing autologous and allogeneic hematopoietic stem cell transplantation from March 2015 to March 2017. The mean caloric and protein intake were evaluated in three different intervals (P1: from admission to the day before transplantation, P2: from the transplantation day to the day before engraftment, P3: from the engraftment day to the day of hospital discharge). Body mass index, weight loss, gastrointestinal symptoms and use of nutritional therapy were also evaluated.ResultsThirty-five patients were included in this study (25 autologous and ten allogeneic). The majority (62.6%) were overweight at admission. The median and percentage weight loss were 3.2 kg and 4.6%, respectively. A nutritional supplement was provided to 33 patients for a median of nine days. The most prevalent gastrointestinal symptoms were nausea (91.4%), vomiting (88.6%) and diarrhea (80%). The mean caloric and protein intake and adequacy of patients were 1569.0 ± 443.3 Kcal (73.6 ± 22.1%) and 66 ± 22.8 g (61.9 ± 20%), respectively. The allogeneic group presented lower intake and caloric and protein adequacy throughout hospitalization, in particular in P2, compared to the autologous patients.ConclusionThe patients presented deterioration of nutritional status during hospitalization with the reduction in food intake being greater in patients submitted to allogeneic transplantation.

show abstract

“…Energy and protein deficit as well as weight loss were also explored by other researchers which found that low energetic and protein intake was related to mortality among critically ill patients in CTUs [27][28][29]. Once more, on the studies mentioned, the patients had other clinical conditions rather than HSCT.…”

Section: Discussionmentioning

confidence: 99%

Pre-transplant arm muscle area: a simple measure to identify patients at risk

Thomaz

Silvério

Campos

et al. 2015

Support Care Cancer

View full text Add to dashboard Cite

show abstract

Comparação de métodos de avaliação nutricional empregados no acompanhamento de pacientes submetidos a transplante de células-tronco hematopoéticas alogênico

Abstract: 4Pacientes submetidos a transplante de células-tronco hematopoéticas alogênico (TCTH alo)

Cited by 7 publications

References 15 publications

Nutritional status of patients submitted to transplantation of allogeneic hematopoietic stem cells: a retrospective study

Nutritional status of patients submitted to transplantation of allogeneic hematopoietic stem cells: a retrospective study

Caloric and protein intake in different periods of hospitalization of patients undergoing hematopoietic stem cell transplantation

Pre-transplant arm muscle area: a simple measure to identify patients at risk

Contact Info

Product

Resources

About