Compact water-window x-ray microscopy with a droplet laser-plasma source

Hertz, Hans M.; Berglund, Magnus; Johansson, Göran A.; Peuker, M.; Wilhein, Thomas; Brismar, Hjalmar

doi:10.1063/1.1291239

Cited by 6 publications

(5 citation statements)

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“…Figure 6 shows an image of a dehydrated COS‐7 cell recorded with a pixel element size of 36 × 36 nm 2 using 5 min exposure time. We note the much higher transmission in the thick central part of the cell with the present λ= 2.48 nm microscope compared to the λ= 3.37 nm microscope (Hertz et al , 2000). The employed adherent COS‐7 cells, derived from foetal monkey kidney, were cultured in Dulbecco's modified eagles medium ( Sigma‐Aldrich ) containing 10% foetal bovine serum ( Invitrogen ), 1% penicillin streptomycin ( Sigma‐Aldrich ), and 1% L‐glutamine ( Sigma‐Aldrich ).…”

Section: Resultscontrasting

confidence: 48%

High‐resolution compact X‐ray microscopy

Takman

Stollberg

Johansson

et al. 2007

Journal of Microscopy

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153

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SummaryWe demonstrate compact full-field soft X-ray transmission microscopy with sub 60-nm resolution operating at λ = 2.48 nm. The microscope is based on a 100-Hz regenerative liquid-nitrogen-jet laser-plasma source in combination with a condenser zone plate and a micro-zone plate objective for highresolution imaging onto a 2048 × 2048 pixel CCD detector. The sample holder is mounted in a helium atmosphere and allows imaging of both dry and wet specimens. The microscope design enables fast sample switching and the sample can be prealigned using a visible-light microscope. High-quality images can be acquired with exposure times of less than 5 min. We demonstrate the performance of the microscope using both dry and wet samples.

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Section: Resultscontrasting

confidence: 48%

High‐resolution compact X‐ray microscopy

Takman

Stollberg

Johansson

et al. 2007

Journal of Microscopy

Self Cite

153

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“…The interest in laser-plasma sources is stimulated by potential innovative applications, where intensive sources of monochromatic radiation are required. If the objective is to develop SXR microscopy [2][3][4] of biological samples [5][6][7], the preference is given to a radiation with a wavelength in the "water window" spectral range (i.e. 2.3 -4.4 nm).…”

Section: Introductionmentioning

confidence: 99%

Gas-Puff Target for Laser-Producing Plasma SXR Source

et al. 2019

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“…Multilayer x-ray optics have many useful applications such as x-ray microscopy, 1,2 x-ray astronomy, 3,4 x-ray lithography, 5 x-ray microanalysis. 6 In particular, multilayer mirrors for the water window region (λ=2.2-4.4 nm) has an important application when used as optical elements in microscopy of biological specimens, due to the large absorption contrast between protein and water.…”

Section: Introductionmentioning

confidence: 99%

<title>Enhanced soft x-ray reflectivity of Cr/Sc multilayers by ion-assisted sputter deposition</title>

et al. 2001

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Cr/Sc multilayers have been grown on Si substrates using DC magnetron sputtering. The multilayers are intended as condenser mirrors in a soft x-ray microscope operating at the wavelength 3.374 nm. They were designed for normal reflection of the first and second order with multilayer periods of 1.692 nm and 3.381 nm, and layer thickness ratios of 0.471 and 0.237, respectively. At-wavelength soft x-ray reflectivity measurements were carried out using a reflectometer with a compact soft x-ray laser-plasma source. The multilayers were irradiated during growth with Ar ions, varying both in energy (9-113 eV) and flux, in order to stimulate the ad-atom mobility and improve the interface flatness. It was found that to obtain a maximum soft x-ray reflectivity with a low flux (Cr=0.76, Sc=2.5) of Ar ions a rather high energy of 53 eV was required. Such energy also caused intermixing of the layers. By the use of a solenoid surrounding the substrate, the arriving ion-to-metal flux ratio could be increased 10 times and the ion energy could be decreased. A high flux (Cr=7.1, Sc=23.1) of low energy (9 eV) Ar ions founded the most favourable growth condition in order to limit the intermixing with a subsistent surface flatness.

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Compact water-window x-ray microscopy with a droplet laser-plasma source

Cited by 6 publications

References 0 publications

High‐resolution compact X‐ray microscopy

High‐resolution compact X‐ray microscopy

Gas-Puff Target for Laser-Producing Plasma SXR Source

<title>Enhanced soft x-ray reflectivity of Cr/Sc multilayers by ion-assisted sputter deposition</title>

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