Comorbidity of irritable bowel syndrome in general practice: a striking feature with clinical implications

Vandvik, Per Olav; Wilhelmsen, Ingvard; Ihlebæk, Camilla; Farup, Per G.

doi:10.1111/j.1365-2036.2004.02250.x

Cited by 142 publications

(119 citation statements)

References 38 publications

(84 reference statements)

Supporting

Mentioning

102

Contrasting

Unclassified

Order By: Relevance

“…In addition, nongastrointestinal somatic disorders and psychiatric disorders occur frequently in IBS (4,5). Comorbidity of IBS has been associated with increased use of health resources, impaired quality of life and poor outcome (6).…”

Section: Introductionmentioning

confidence: 99%

Irritable bowel syndrome subtypes: Clinical and psychological features, body mass index and comorbidities

Nagasako¹,

Montes²,

Lorena³

et al. 2015

Rev Esp Enferm Dig

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Irritable bowel syndrome subtypes: Clinical and psychological features, body mass index and comorbidities

Nagasako¹,

Montes²,

Lorena³

et al. 2015

Rev Esp Enferm Dig

View full text Add to dashboard Cite

show abstract

“…However, IBS is also often accompanied by another extra-intestinal symptoms, as asthma and cerebral pain symptoms as primary headache. The pathophysiology mechanisms suggest that IBS patients with one or more somatic comorbitdities might represent a separate sub-group (6,17,20,29,39,42) .…”

Section: Discussionmentioning

confidence: 99%

“…IBS affects 15%-23% of the general population and is the most common reason for patients and generalists to consult gastroenterologists In addition, our data showed that the percentage of IBS diagnosis and PH is in accordance with other studies. IBS affects 15%-23% of the general population and is the most common reason for patients and general practitioners to consult gastroenterologists (6,20,26,29,31,39,42) . Globally, the percentage of adult population with an active headache disorder is 47%.…”

Section: Discussionmentioning

confidence: 99%

“…The nongastrointestinal nonpsychiatric disorders with the best documented association are fibromyalgia, chronic fatigue syndrome, temporomandibular joint disorder and chronic pelvic pain (1,5,20) . In addition, IBS is often accompanied by other extra-intestinal symptoms, as asthma and cerebral pain symptoms as primary headache (39) . Chronic headache was reported by 34%-50% of IBS patients in three controlled demographical studies, which is significantly higher compared to healthy subjects.…”

Section: Introductionmentioning

confidence: 99%

“…They can contribute to the definition of new pathogenetic hypothesis to be tested experimentally (8,22,23,31) . To knowledge and assessment of comorbidities somatic symptoms in IBS patients might allow to identify sub-groups of IBS patients with special characteristics and lead to adaptation of therapeutic concept (5,39) .…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

THE PREVALENCE AND CLINICAL CHARACTERISTICS OF PRIMARY HEADACHE IN IRRITABLE BOWEL SYNDROME: a subgroup of the functional somatic syndromes

Soares

Moreira-filho

Maneschy

et al. 2013

Arq. Gastroenterol.

View full text Add to dashboard Cite

-Context -The irritable bowel syndrome and primary headache are two chronic diseases characterized by symptoms of recurring pain and affect approximately 10%-20% of the general population. Objectives -To study the prevalence of primary headache in volunteers with irritable bowel syndrome in a Brazilian urban community. Methods -It was evaluated the prevalence of primary headache associated with irritable bowel syndrome in adult volunteers 330 no patients.The protocol included the Rome III criteria, international classification of Headaches, later divided into four groups: I-Irritable bowel syndrome (n = 52), II-Primary headache (n = 45), III-Irritable bowel syndrome (n = 26) and headache, and IV-Controls (207). Results -We not found significant difference in the average age of the four groups and the diagnosis of irritable bowel syndrome, primary headache and their association was more frequent in females. The frequent use of analgesics was greater in groups II and III. Conclusion -Our results suggest that irritable bowel syndrome and primary headache are also common in third world countries. The frequency in use of analgesics in association between the two entities was relevant. The identification of irritable bowel syndrome patients with different clinical sub-types could improve the therapeutics options and the prevention strategies. HEADINGS -Irritable bowel syndrome. Headache. Comorbidities.

show abstract

Irritable Bowel Syndrome

Spiller

2012

Textbook of Clinical Gastroenterology and Hepatology

View full text Add to dashboard Cite

Irritable bowel syndrome (IBS) is a functional gastrointestinal disease with a high population prevalence. The disorder can be debilitating in some patients, whereas others may have mild or moderate symptoms. The most important single risk factors are female sex, younger age and HHS Public AccessAuthor manuscript Nat Rev Dis Primers. Author manuscript; available in PMC 2016 August 26. Published in final edited form as:Nat Rev Dis Primers. ; 2: 16014. doi:10.1038/nrdp.2016.14. Author Manuscript Author ManuscriptAuthor ManuscriptAuthor Manuscript preceding gastrointestinal infections. Clinical symptoms of IBS include abdominal pain or discomfort, stool irregularities and bloating, as well as other somatic, visceral and psychiatric comorbidities. Currently, the diagnosis of IBS is based on symptoms and the exclusion of other organic diseases, and therapy includes drug treatment of the predominant symptoms, nutrition and psychotherapy. Although the underlying pathogenesis is far from understood, aetiological factors include increased epithelial hyperpermeability, dysbiosis, inflammation, visceral hypersensitivity, epigenetics and genetics, and altered brain-gut interactions. IBS considerably affects quality of life and imposes a profound burden on patients, physicians and the health-care system. The past decade has seen remarkable progress in our understanding of functional bowel disorders such as IBS that will be summarized in this Primer.Irritable bowel syndrome (IBS) is a functional bowel disorder (that is, not associated with structural or biochemical abnormalities that are detectable with the current routine diagnostic tools) characterized by abdominal pain or discomfort, stool irregularities and bloating (BOX 1). Symptoms can be debilitating in many individuals, but may be mild or moderate in other patients. In addition, IBS is often associated with other somatic comorbidities (for example, pain syndromes, overactive bladder and migraine), psychiatric conditions (including depression and anxiety) and visceral sensitivity. The population prevalence of IBS is high (~11%) and the condition has considerable consequences for quality of life (QOL) that are comparable to other chronic diseases, such as diabetes mellitus and hepatitis. IBS is diagnosed based on symptoms, and a distinction is made between the following subtypes of IBS: IBS with pain or discomfort and predominant constipation (IBS-C), IBS with diarrhoea (IBS-D), mixed IBS (IBS-M) and unsubtyped IBS (IBS-U) (FIG. 1).Moreover, other diseases (including other functional gastrointestinal diseases, such as functional dyspepsia and gastroesophageal reflux disease) that may cause the typical IBS symptoms should be excluded. Although a substantial proportion of patients will experience spontaneous remission over time, there is currently no treatment that cures IBS; relief of symptoms is the most that can be achieved.IBS is a multifactorial disease. Hence, the underlying pathogenesis is considered complex and the precise molecular pathophysiology is far...

show abstract

Comorbidity of irritable bowel syndrome in general practice: a striking feature with clinical implications

Cited by 142 publications

References 38 publications

Irritable bowel syndrome subtypes: Clinical and psychological features, body mass index and comorbidities

Irritable bowel syndrome subtypes: Clinical and psychological features, body mass index and comorbidities

THE PREVALENCE AND CLINICAL CHARACTERISTICS OF PRIMARY HEADACHE IN IRRITABLE BOWEL SYNDROME: a subgroup of the functional somatic syndromes

Irritable Bowel Syndrome

Contact Info

Product

Resources

About