Comorbid bipolar disorder among patients with conversion disorder

Karamustafalıoğlu, Oğuz; Özçelik, Başak; Toker, Sinem Gönenli; Bakım, Bahadır; Ceylan, Yasemin; Akpınar, Abdullah; Uzun, U.; Tankaya, Onur; Çevik, Mehmet Uğur; Yavuz, Betül; Karabulut, Vahap; Toprak, E.

doi:10.5455/jmood.20130116052209

Cited by 4 publications

(3 citation statements)

References 20 publications

(16 reference statements)

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“…A history of physical and sexual trauma in childhood was found to be prevalent in our study. Similar to the findings of previous studies (3,16,17,24,40), 53.3% of our CD patients reported a history of physical trauma and 25% reported sexual trauma in their childhood. Sexual and physical abuse, as well as physical neglect, have been reported in patients with dissociative symptoms (17,35,36,42).…”

Section: Discussionsupporting

confidence: 91%

See 1 more Smart Citation

Conversion Disorder Comorbidity and Childhood Trauma

Akyüz

Gokalp

Erdiman

et al. 2017

Arch Neuropsychiatr

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Section: Discussionsupporting

confidence: 91%

“…Consistent with these data, a psychiatric co-morbidity was present in 73.3% of our CD patients. The most common co-morbid psychiatric diagnoses were depression (50%) and dissociative disorder (48.3%); this is also similar to the findings of previous studies (11,23,24,40).…”

Section: Discussionsupporting

confidence: 90%

Conversion Disorder Comorbidity and Childhood Trauma

Akyüz

Gokalp

Erdiman

et al. 2017

Arch Neuropsychiatr

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“…Gerardo et al found that 4% of patients with pseudo-seizure had bipolar disorder (2). Karamustafalioglu et al (8) showed 28% of bipolar disorder comorbidities in patients with conversion disorder.…”

Section: Introductionmentioning

confidence: 99%

Bipolar Spectrum in Patients with Conversion Disorder

Ardestani

Yasamy

Borna

et al. 2020

Iran J Psychiatry Behav Sci

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Background: The frequency of bipolar spectrum in patients with conversion disorder is not well known, while it is important to be aware of comorbid bipolarity in the management of conversion disorder. Objectives: The study aimed to identify the frequency of bipolar spectrum disorder among people with conversion disorder and the factors associated with this comorbidity. Methods: The participants were 96 consecutive patients aged 18 - 65 years, referring to the emergency department or admitted to the psychiatric wards of two university general hospitals in Tehran, Iran, in 2019. Patients fulfilled the DSM-IV criteria for conversion disorder based on the structured clinical interview (SCID). The Mood Disorder questionnaire (MDQ) was used to identify bipolar spectrum disorder. Demographic characteristics and other relevant correlated factors were also recorded using a checklist. Data were analyzed using Pearson chi-square/Fisher’s exact test and logistic regression model. Results: The frequency of bipolar spectrum disorder based on the MDQ was 35.4% in patients with conversion disorder. The results of the logistic regression model using the Backward Conditional method showed that only two variables, namely antidepressant-induced mania/hypomania (OR = 39; CI 95%: 4.56 - 333.7) and history of hospitalization in the psychiatric ward (OR = 7.1, CI 95%: 2.05 - 24.65), remained as associated factors after controlling for other variables. Conclusions: Our study showed a higher frequency of bipolar spectrum disorder in patients with conversion disorder than did previous epidemiological studies in Iran and other countries. Such significant comorbidity should discourage potentially harmful off-label use of antidepressants for the treatment of conversion disorder instead of looking for other underlying psychiatric or social problems. Further research is suggested in this area.

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