Medically unexplained somatic symptoms and bipolar spectrum disorders: A systematic review and meta-analysis

Edgcomb, Juliet Beni; Tseng, Chi‐Hong; Kerner, Berit

doi:10.1016/j.jad.2016.06.029

Cited by 18 publications

(19 citation statements)

References 58 publications

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“…Somatic symptoms are prevalent in people with some kinds of psychiatric disorders. For example, about 48% of both bipolar and unipolar depressions show higher somatic symptoms than general population [9].…”

Section: Introductionmentioning

confidence: 99%

Explanation of somatic symptoms by mental health and personality traits: application of Bayesian regularized quantile regression in a large population study

et al. 2019

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Background Somatic syndrome is one of the remarkably prevalent issues in primary health care and subspecialty settings. We aimed to elucidate multidimensional associations between somatic symptoms with major mental problems and personality traits in the framework of the quantile regression model with a Bayesian approach. Methods A total of 4763 employees at Isfahan University of Medical Sciences and Health Services in Isfahan province, Iran, filled out four validated questionnaires including Hospital Anxiety and Depression Scale (HADS), NEO Questionnaire, General Health Questionnaire (GHQ) and PHQ-15 for somatic symptom severity. In addition, Functional Gastrointestinal Disorders (FGIDs) were determined using Rome IV criteria. Exploratory Factor Analysis (EFA) and Bayesian regularized quantile regression with adaptive LASSO penalization were applied for reduced dimension of somatic symptoms and variable selection and parameter estimation, respectively. Results The 25 major somatic symptoms were grouped into four factors including general, upper gastrointestinal, lower gastrointestinal and respiratory by EFA. Stress, depression, and anxiety had significant effects on all of the four extracted factors. The effect of anxiety in each four extracted factors was more than stress and depression. Neuroticism and agreeableness had significant effects on all of the four extracted factors, generally ( p < 0.05). Conclusions Given the high prevalence of somatic symptoms and psychosomatic complaints in correlation with the diverse range of mental co-morbidities, developing more detailed diagnostic tools and methods is crucial; nonetheless, it seems that providing better interdisciplinary approaches in general medical practice is groundwork.

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Section: Introductionmentioning

confidence: 99%

Explanation of somatic symptoms by mental health and personality traits: application of Bayesian regularized quantile regression in a large population study

et al. 2019

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“…In patients with bipolar disorder, the prevalence of somatic symptoms is approximately 48%. This is higher than in any mixed psychiatric sample or the general population . These bodily symptoms are often debilitating and impairing.…”

Section: Discussionmentioning

confidence: 74%

“…This is higher than in any mixed psychiatric sample or the general population. 2 These bodily symptoms are often debilitating and impairing. Hence, careful monitoring of all bodily symptoms described by a patient suffering from bipolar disorder is essential.…”

Section: Discussionmentioning

confidence: 99%

“…This limits early and accurate psychological diagnosis being made, delaying the institution of appropriate treatment. Interestingly patients suffering from bipolar disorder are far more likely than patients with other psychiatric disorders or the general population to present clinically with somatic complaints …”

Section: Introductionmentioning

confidence: 99%

“…Interestingly patients suffering from bipolar disorder are far more likely than patients with other psychiatric disorders or the general population to present clinically with somatic complaints. 2 The following case highlights the importance of considering the diagnosis of a somatoform symptom disorder in patients with bipolar illness and emphasises the usefulness of a thorough diagnostic interview upon which to base treatment.…”

Section: Introductionmentioning

confidence: 99%

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