Comorbid anxiety and depression (CAD) at early stages of the pregnancy. A multicultural cross-sectional study

González-Mesa, Ernesto; Kabukçuoğlu, Kamile; Blasco, Marta; Körükçü, Öznur; Ibrahim, Noha; González-Cazorla, Ana; Cazorla, Olga

doi:10.1016/j.jad.2020.03.086

Cited by 27 publications

(28 citation statements)

References 24 publications

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“…This finding is in line with the studies conducted in Pakistan 13.5% [6], Spain (9.5%) [7], South Africa (7.6% early and 9.7% in late pregnancy) [9] and a meta-analysis conducted by Falah and coworkers (9.5%) [4]. On the other hand, this finding is higher than the study conducted in Singapore (5.0%) [5] and very much lower than the study in Turkey (47.6%) [7]. These discrepancies might be due to differences in anxiety and depression measurement scales and cut-off point used, geographical settings, pregnancy trimester, socio-economic status and socio-cultural differences.…”

Section: Plos Onesupporting

confidence: 93%

“…Thiagayson and associates also reported that 5% of Singaporean women had prenatal CAD [5]. Likewise, studies from Spain, Turkey and Pakistan also demonstrated that 9.5%, 47.6% and 13.5% of pregnant women encountered CAD respectively [6,7].…”

Section: Introductionmentioning

confidence: 89%

“…Household food insecurity also increases the odds of mental health problems during pregnancy [13][14][15]. Moreover, poor emotional support is reported as one of the single most predictors for CAD symptoms in a multinational study conducted in Turkey and Spain [7].…”

Section: Introductionmentioning

confidence: 99%

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Comorbid anxiety and depression: Prevalence and associated factors among pregnant women in Arba Minch zuria district, Gamo zone, southern Ethiopia

et al. 2021

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Introduction Prenatal anxiety and depression are major health problems all over the world. The negative sequela of prenatal comorbid anxiety and depression (CAD) has been suggested to be higher than that of anxiety or depression alone. CAD increases the odds of preterm birth, low birth weight, prolonged labor, operative deliveries, postpartum psychiatric disorders and long term cognitive impairment for the newborn. Despite its significant ill consequences, there is a dearth of studies in low-and middle-income countries. So far, to the best of our knowledge, no study assessed the prevalence of CAD in Ethiopia. Hence, the purpose of this study was to assess CAD and associated factors among pregnant women in Arba Minch Zuria district, Gamo zone, southern Ethiopia. Methods A community-based cross-sectional study was conducted among 676 pregnant women from January 01 to November 30, 2019. Patient Health Questionnaire 9-item (PHQ-9) and Generalized Anxiety Disorder 7-item (GAD-7) scales were used to assess depression and anxiety respectively. The data were collected electronically using an open data kit (ODK) collect android application and analyzed using Stata version 15.0. Bivariate and multivariable analyses were carried out to identify factors associated with CAD using binary logistic regression. Statistical significance was set at p-value < 0.05. Results A total of 667 women were involved. The prevalence of CAD was 10.04% [95% confidence interval (CI): 7.76, 12.33]. Being married [adjusted odds ratio (AOR): 0.16, 95% CI: 0.05, 0.56], categorized in the highest wealth quintile [AOR: 2.83, 95% CI: 1.17, 6.84], having medical illness [AOR: 3.56, 95% CI: 1.68, 7.54], encountering pregnancy danger signs [AOR: 2.66, 95% CI: 1.06, 6.67], experiencing life-threatening events [AOR: 2.11, 95% CI: 1.15, 3.92] and household food insecurity [AOR: 3.51, 95% CI: 1.85, 6.64] were significantly associated with CAD. Conclusions In general, one in every ten women faced CAD in the study area. Nutritional interventions, early identification and treatment of pregnancy-related illness and medical ailments, prenatal mental health problems screening and interventions are imperative to minimize the risk of CAD in pregnant women.

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Section: Plos Onesupporting

confidence: 93%

Section: Introductionmentioning

confidence: 89%

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Comorbid anxiety and depression: Prevalence and associated factors among pregnant women in Arba Minch zuria district, Gamo zone, southern Ethiopia

et al. 2021

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“…Our point estimates of the prevalence of comorbid anxiety and mild-to-severe depression (13.5%) and moderate-to-severe depression (9.2%) were higher than the corresponding rates of 9.5% and 6.3%, respectively, reported in the systematic review with studies predominantly from high-income countries [ 7 ]. Prevalence of comorbidity is influenced by geographic location and cultural milieu [ 22 , 23 ]. Differences in prevalence of comorbidity between a cohort of pregnant Spanish (26.9%) and Turkish (47%) women were attributed to sociocultural characteristics and practices including number of living children, quality of relationship with husband, family structure such as extended family living in the household, and ability to work given educational preparation [ 22 , 23 ].…”

Section: Discussionmentioning

confidence: 99%

“…Prevalence of comorbidity is influenced by geographic location and cultural milieu [ 22 , 23 ]. Differences in prevalence of comorbidity between a cohort of pregnant Spanish (26.9%) and Turkish (47%) women were attributed to sociocultural characteristics and practices including number of living children, quality of relationship with husband, family structure such as extended family living in the household, and ability to work given educational preparation [ 22 , 23 ].…”

Section: Discussionmentioning

confidence: 99%

Comorbid Anxiety and Depression among Pregnant Pakistani Women: Higher Rates, Different Vulnerability Characteristics, and the Role of Perceived Stress

Premji

Lalani

Shaikh

et al. 2020

IJERPH

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Anxiety and depression commonly co-occur during pregnancy and may increase risk of poor birth outcomes including preterm birth and low birth weight. Our understanding of rates, patterns, and predictors of comorbid anxiety and depression is hindered given the dearth of literature, particularly in low- and middle-income (LMI) countries. The aim of this study is (1) to explore the prevalence and patterns of comorbid antenatal anxiety and depressive symptoms in the mild-to-severe and moderate-to-severe categories among women in a LMI country like Pakistan and (2) to understand the risk factors for comorbid anxiety and depressive symptoms. Using a prospective cohort design, a diverse sample of 300 pregnant women from four centers of Aga Khan Hospital for Women and Children in Pakistan were enrolled in the study. Comorbid anxiety and depression during pregnancy were high and numerous factors predicted increased likelihood of comorbidity, including: (1) High level of perceived stress at any time point, (2) having 3 or more previous children, and (3) having one or more adverse childhood experiences. These risks were increased if the husband was employed in the private sector. Early identification and treatment of mental health comorbidities may contribute to decreased adverse birth outcomes in LMI countries.

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Socioeconomic resources moderate the relationship between maternal prenatal obsessive-compulsive symptoms and infant negative affectivity

Gibbs,

Aubuchon-Endsley

2023

Infant Behavior and Development

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Comorbid anxiety and depression (CAD) at early stages of the pregnancy. A multicultural cross-sectional study

Cited by 27 publications

References 24 publications

Comorbid anxiety and depression: Prevalence and associated factors among pregnant women in Arba Minch zuria district, Gamo zone, southern Ethiopia

Comorbid anxiety and depression: Prevalence and associated factors among pregnant women in Arba Minch zuria district, Gamo zone, southern Ethiopia

Comorbid Anxiety and Depression among Pregnant Pakistani Women: Higher Rates, Different Vulnerability Characteristics, and the Role of Perceived Stress

Socioeconomic resources moderate the relationship between maternal prenatal obsessive-compulsive symptoms and infant negative affectivity

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