Community Willingness to Participate in a Dengue Study in Aceh Province, Indonesia

Harapan, Harapan; Anwar, Samsul; Bustaman, Aslam; Radiansyah, Arsil; Angraini, Pradiba; Fasli, Riny; Salwiyadi, Salwiyadi; Bastian, Reza Akbar; Oktiviyari, Ade; Akmal, Imaduddin; Iqbalamin, Muhammad; Adil, Jamalul; Henrizal, Fenni; Darmayanti, Darmayanti; Pratama, Rovy; Fajar, Jonny Karunia; Setiawan, Abdul Malik; Imrie, Allison; Kuch, Ulrich; Groneberg, David A.; Sasmono, R. Tedjo; Dhimal, Meghnath; Müller, Ruth

doi:10.1371/journal.pone.0159139

Cited by 24 publications

(19 citation statements)

References 69 publications

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“…The data presented in this study was a part of Aceh Dengue Study and the characteristics of the research participants, in part, have been described elsewhere [ 15 , 17 – 20 ]. Briefly, for this specific study, 677 healthy community members were surveyed and 68 (10.0%) participants were excluded from the analysis due to missing information.…”

Section: Resultsmentioning

confidence: 99%

Knowledge, attitude, and practice regarding dengue virus infection among inhabitants of Aceh, Indonesia: a cross-sectional study

et al. 2018

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BackgroundThe Indonesian region of Aceh was the area most severely affected by the earthquake and tsunami of 26 December 2004. Department of Health data reveal an upward trend of dengue cases in Aceh since the events of the tsunami. Despite the increasing incidence of dengue in the region, there is limited understanding of dengue among the general population of Aceh. The aim of this study was to assess the knowledge, attitude, and practice (KAP) regarding dengue among the people of Aceh, Indonesia in order to design intervention strategies for an effective dengue prevention program.MethodsA community-based cross-sectional study was conducted in Aceh between November 2014 and March 2015 with a total of 609 participants living in seven regencies and two municipalities. Information on the socio-demographic characteristics of participants and their KAP regarding dengue was collected using a pre-tested structured questionnaire. The KAP status (good vs. poor) of participants with different socio-demographic characteristics was compared using Chi Square-test, ANOVA or Fisher’s exact test as appropriate. Logistic regression analysis was used to determine the predictors of each KAP domain.ResultsWe found that 45% of participants had good knowledge regarding dengue and only 32% had good attitudes and good dengue preventive practices. There was a significant positive correlation between knowledge and attitudes, knowledge and practice, and attitudes and practice. In addition, people who had good knowledge were 2.7 times more likely to have good attitudes, and people who had good attitudes were 2.2 times more likely to have good practices regarding dengue. The level of education, occupation, marital status, monthly income, socioeconomic status (SES) and living in the city were associated with the knowledge level. Occupation, SES, and having experienced dengue fever were associated with attitudes. Education, occupation, SES and type of residence were associated with preventive practices.ConclusionOur study suggests that dengue prevention programs are required to increase KAP levels regarding dengue in the communities of Aceh.Electronic supplementary materialThe online version of this article (10.1186/s12879-018-3006-z) contains supplementary material, which is available to authorized users.

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Section: Resultsmentioning

confidence: 99%

Knowledge, attitude, and practice regarding dengue virus infection among inhabitants of Aceh, Indonesia: a cross-sectional study

et al. 2018

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“…Several studies have confirmed the assumption that knowledge of dengue favors the adoption of preventive measures that promote the reduction of breeding sites for A. aegypti 13 . Another study has stated that the greater the knowledge, the greater the willingness to participate in research on dengue 14 . This study found that healthcare personnel have a greater knowledge and a greater risk perception in comparison with the general population.…”

Section: Discussionmentioning

confidence: 99%

Risk perception and level of knowledge of diseases transmitted by Aedes aegypti

Menchaca-Armenta

Ocampo-Torres

Hernández-Gómez

et al. 2018

Rev. Inst. Med. trop. S. Paulo

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Diseases caused by viruses such as dengue, chikungunya and zika are mosquito-borne diseases transmitted by Aedes aegypti. We performed a cross-sectional study of healthcare personnel and the general population using questionnaires to identify the level of knowledge, attitudes and practices, and risk perception for dengue, chikungunya and zika. A total of 248 questionnaires were applied, 63.3% to healthcare personnel and 36.7% to the general population. Of the healthcare personnel, 53% were men, and in the general population 74% were women. Nahuatl and Spanish were spoken by both, healthcare personnel (28%) and the general population (23%). The level of knowledge, attitudes and practices and risk perception of the population and personnel showed significant differences (p<0.05). Among healthcare personnel, nurses and vector operating staff had the lowest level of knowledge. On the other hand, the questions with the lowest scores were 1) symptoms of Zika in both groups, 2) circulating dengue serotypes in healthcare personnel and 3) symptoms of chikungunya in the general population. The results of this work allow us to identify information gaps in which knowledge, attitudes and practices, and risk perception need to be increased.

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“…One study specifically identified that women were more likely to participate in a trial because of general altruistic considerations [ 39 ]. In Indonesia, a previous study similarly found that women were more willing to donate their blood for dengue research [ 21 ]. Together, our study on Zika and the previous study on Dengue [ 21 ] indicate that females are likely more willing to participate in health-related research.…”

Section: Discussionmentioning

confidence: 99%

“…Several motivations and barriers have been identified to be associated with WTP in clinical trials [ 18 , 19 , 20 ]. In Indonesia, only one study has been conducted to assess the WTP in a medical related study and found that being female, working as a civil servant, private employee or entrepreneur, having a high socioeconomic status and good knowledge, attitude and practice related to the disease were associated with WTP [ 21 ]. However, new emerging infectious disease with severe complications for infants, such as ZIKV infection, might have additional considerations.…”

Section: Introductionmentioning

confidence: 99%

Willingness to Participate and Associated Factors in a Zika Vaccine Trial in Indonesia: A Cross-Sectional Study

Harapan

Mudatsir

Yufika

et al. 2018

Viruses

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One of the crucial steps during trials for Zika and other vaccines is to recruit participants and to understand how participants’ attitudes and sociodemographic characteristics affect willingness to participate (WTP). This study was conducted to assess WTP, its explanatory variables, and the impact of financial compensation on WTP in Indonesia. A health facility-based cross-sectional study was conducted in eleven regencies in the Aceh and West Sumatra provinces of Indonesia. Participants were recruited via a convenience sampling method and were interviewed. The associations between explanatory variables and WTP were assessed using a two-step logistic regression analysis. A total of 1,102 parents were approached, and of these 956 (86.8%) completed the interview and were included in analysis. Of those, 144 (15.1%) were willing to participate in a Zika vaccine trial without a financial compensation. In the multivariate analysis, WTP was tied to an age of more than 50 years old, compared to 20–29 years (odds ratio (OR): 5.0; 95% confidence interval (CI): 2.37–10.53), to being female (OR: 2.20; 95% CI: 1.11–4.37), and to having heard about Zika (OR: 2.41; 95% CI: 1.59–3.65). Participants’ WTP increased gradually with higher financial compensation. The rate of WTP increased to 62.3% at the highest offer (US$ 350.4), and those who were still unwilling to participate (37.7%) had a poorer attitude towards childhood vaccination. This study highlights that pre-existing knowledge about Zika and attitudes towards childhood vaccination are important in determining community members being willing to participate in a vaccine trial. Financial incentives are still an important factor to enhance participant recruitment during a vaccine trial.

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Community Willingness to Participate in a Dengue Study in Aceh Province, Indonesia

Cited by 24 publications

References 69 publications

Knowledge, attitude, and practice regarding dengue virus infection among inhabitants of Aceh, Indonesia: a cross-sectional study

Knowledge, attitude, and practice regarding dengue virus infection among inhabitants of Aceh, Indonesia: a cross-sectional study

Risk perception and level of knowledge of diseases transmitted by Aedes aegypti

Willingness to Participate and Associated Factors in a Zika Vaccine Trial in Indonesia: A Cross-Sectional Study

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