Community Care of Corneal Ulcers

Park, Steve B.; Aquavella, James V.

doi:10.1016/s0002-9394(14)74479-4

Cited by 105 publications

(67 citation statements)

References 20 publications

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“…Estima-se que um terço das úlceras corneanas supostamente infecciosas têm cultura negativa (11)(12) . Cerca de um quarto das culturas para fungos apresentam-se positivas apenas depois de Figura 4 -Cultura para fungos: Fusarium sp 2 semanas (13) .…”

Section: Discussionunclassified

Microscopia confocal in vivo no diagnóstico de ceratite fúngica: relato de caso

Victor¹,

Alves²,

Nosé³

2006

Arq. Bras. Oftalmol.

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Section: Discussionunclassified

Microscopia confocal in vivo no diagnóstico de ceratite fúngica: relato de caso

Victor¹,

Alves²,

Nosé³

2006

Arq. Bras. Oftalmol.

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“…5 Nevertheless, several recent reports describe a decrease in the frequency with which ophthalmologists perform standard cultures, and an increasing use of transport media for submitting samples to microbiology laboratories for evaluation. 6,10,11 The disparity between traditional academic and actual practice can be explained by laboratory costs, time constraints in busy office settings, the cost in maintaining fresh media in an office setting, and the difficulty in transporting the inoculated plates, as they require immediate transportation in a special conditions. Another reason can be the sense that empiric treatment is adequate for the majority of cases.…”

Section: Discussionmentioning

confidence: 99%

“…5 Nevertheless, it was reported in Southern California that as many as 48% of patients with clinically suspected infectious keratitis received antibiotic therapy without prior culture, and only 22% of the general ophthalmologists were found to maintain culture media supplies in their offices. 6 Several reasons have been offered as explanations for the disparity between the traditionally recommended evaluation of infectious keratitis and actual practice. These explanations include laboratory costs, time constraints in busy office settings, the cost of maintaining fresh media in an office setting, and the difficulty of transporting the inoculated plates, as they require immediate transportation in special conditions.…”

Section: Introductionmentioning

confidence: 99%

Broth cultures yield vs traditional approach in the workup of infectious keratitis

Kratz

Levy

Klemperer

et al. 2005

Eye

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Broth cultures yield vs traditional approach in the workup of infectious keratitisA Kratz, J Levy, I Klemperer and T Lifshitz Abstract Purpose To elucidate whether BACTEC Peds Plus F broth, usually used for culturing body fluids in paediatric departments, can be used for corneal cultures from cases with clinically suspected infectious keratitis, and to compare yields between this method and traditional methods (blood agar, chocolate agar, a fungal media, and swab transport media). Methods All cases with newly diagnosed, nonviral, clinically suspected infectious keratitis with no prior antibiotic therapy, were cultured both in the BACTEC Peds Plus F broth and the traditional method. McNemar's test was used for pairwise comparisons of the rates of positive growth between the two groups. Results In total, 30 eyes were included in this study. The growth rates for the traditional method and the BACTEC broth were similar (50.0 and 53.33%, respectively, P ¼ 1.0). The overall growth rate for the two methods combined was 73.33%, which is 45.29% higher than the reported yield in the literature (average of 50.47%). Conclusions Our results show that BACTEC Peds Plus F broth can be used successfully in the work-up of clinically suspected infectious keratitis. The method has, apparently, several advantages over the 'Traditional method:' time-savings, as only one medium needs to be inoculated, transportation to the laboratory is simpler as there is no need for immediate incubation, and there is no need to keep and maintain a supply of fresh agar media. This method is especially suitable for office settings and remote clinics, but also can be used in hospital setting, as an adjunct, when available, to increase the growth yield.

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“…8,26 More importantly, the access to the diagnostic tools described in this review are not available in multiple regions of the World. In order to decrease the need of diagnostic test and to simplify the diagnosis of patients with PIK the use of artificial neural networks (ANN) may have a role in the future.…”

Section: Case Nomentioning

confidence: 99%

“…The majority of the PIK cases respond well to this type of management. 8 The small numbers of cases that do not respond to the treatment are the cases that offer a diagnostic and therapeutic challenge to the corneal specialist.…”

Section: Introductionmentioning

confidence: 99%

What is causing the corneal ulcer? Management strategies for unresponsive corneal ulceration

Amescua

Miller

Alfonso

2011

Eye

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Infectious keratitis represents a significant cause of ocular morbidity in the United States. The work-up and treatment of presumed infectious keratitis (PIK) has changed in the past two decades. The development of newer topical antibiotics has enabled broad-spectrum antibiotic coverage with good tissue penetration. The majority of PIK cases respond well to this strategy. The small numbers of cases that do not respond to the treatment are the cases that offer a diagnostic and therapeutic challenge. This review will describe different algorithms that can be followed for the successful management of patients with difficult or progressive PIK. These algorithms are based on scientific work and on our empirical clinical experience. The review will also present three different clinical cases of PIK that were managed according to the algorithms presented in this review.

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Community Care of Corneal Ulcers

Cited by 105 publications

References 20 publications

Microscopia confocal in vivo no diagnóstico de ceratite fúngica: relato de caso

Microscopia confocal in vivo no diagnóstico de ceratite fúngica: relato de caso

Broth cultures yield vs traditional approach in the workup of infectious keratitis

What is causing the corneal ulcer? Management strategies for unresponsive corneal ulceration

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