Community-associated meticillin-resistant Staphylococcus aureus as a cause of hospital-acquired infections

Skov, Robert; Jensen, Kai

doi:10.1016/j.jhin.2009.07.004

Cited by 98 publications

(83 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moreover, these strains moving into the hospital settings increasingly caused HCA infections including ventilator associated pneumonia, surgical site infections and bacteremia. 33,34 They usually remain susceptible to many non-beta-lactam antibiotics including clindamycin and TMP-SMX. 27 Coagulase-negative streptococci are the most common cause nosocomial BSIs and are responsible almost one third of all healthcare associated bacteremia.…”

Section: Gram-positive Bacteriamentioning

confidence: 99%

Epidemiology of antimicrobial resistance in bloodstream infections

2016

View full text Add to dashboard Cite

Antimicrobial resistance in bacterial pathogens is a worldwide challenge leading high morbidity and mortality in clinical settings. Multidrug resistant patterns in gram-positive and -negative bacteria have resulted in difficult-to-treat or even untreatable infections with conventional antimicrobials. Since the early identification of causative microorganisms and their antimicrobial susceptibility patterns in patients with bacteremia and other serious infections is lacking in many healthcare institutions, broad spectrum antibiotics are liberally and mostly unnecessarily used. Such practice has, in turn, caused dramatic increases in emerging resistance and when coupled with poor practice of infection control, resistant bacteria can easily be disseminated to the other patients and the environment. Thus, availability of updated epidemiological data on antimicrobial resistance in frequently encountered bacterial pathogens will be useful not only for deciding on empirical treatment strategies, but also devising an effective antimicrobial stewardship program in hospitals.

show abstract

Section: Gram-positive Bacteriamentioning

confidence: 99%

Epidemiology of antimicrobial resistance in bloodstream infections

2016

View full text Add to dashboard Cite

show abstract

“…Mathematical models appear to predict that they will ultimately displace traditional HA-MRSA strains in the healthcare setting [23,30]. A high number of CA-MRSA infections are being observed in the USA, but also in increasing frequency in other parts of the world, reaching pandemic proportions [23,30,33]. The fact that the CA-MRSA epidemic is particularly severe in the USA is likely due to single epidemic clone USA300.…”

Section: Epidemiology Of Mrsamentioning

confidence: 99%

“…According to the current definition, CA-MRSA infections are those for which the onset of infection is within 48 h of admission to the hospital with no previous history of hospitalization in the past year, whereas HA-MRSA is defined by the onset of infection occurring after 48 h of hospital admission [33]. The most contemporary definitions now incorporate both MIC and molecular criteria.…”

Section: Epidemiology Of Mrsamentioning

confidence: 99%

“…Until recently, studies of ocular MRSA infections have generally been limited to case reports and small case series from single institutions [1,91]. The scant information on ocular infections and the variety of definitions for CA-MRSA [9,33,92,94] makes comparing and contrasting published studies difficult. In addition, many of the earlier studies on MRSA ophthalmic infections do not distinguish CA-MRSA from HA-MRSA entities.…”

Section: Spectrum Of Eye Diseasementioning

confidence: 99%

See 1 more Smart Citation

Methicillin-Resistant Staphylococcus aureus and the Eye: Current Concepts and Management Strategies

Ritterband

2013

Curr Ophthalmol Rep

View full text Add to dashboard Cite

Methicillin-resistant Staphylococcus aureus (MRSA) remains one of the most important causes of nosocomial infections worldwide. This review explores the history and epidemiology of MRSA infections with a detailed analysis of its molecular subtyping, target populations, virulence factors, and modes of transmission. In addition, it specifically discusses the spectrum of eye diseases caused by MRSA, reviews the current ophthalmic literature, addresses the controversy regarding ophthalmic antibiotic resistance to MRSA, and examines alternative treatment strategies.

show abstract

“…When caused by Methicillin-resistant Staphylococcus aureus, infection rates increase, including surgical site infection, pneumonias associated with mechanical ventilation and bacteremia (15,(19)(20) . These studies, however, do not directly relate the presence of previous community-acquired infections with the occurrence of infections caused by resistant microorganisms.…”

Section: Mortality-associated Factorsmentioning

confidence: 99%

Bacterial Resistance and Mortality in an Intensive Care Unit

Oliveira

Silva

Diaz

et al. 2010

Rev. Latino-Am. Enfermagem

View full text Add to dashboard Cite

The goal was to identify risk factors for healthcare-associated infections by resistant Resistencia bacteriana y mortalidad en un Centro de Terapia IntensivaSe objetivó identificar factores de riesgo para el desarrollo de infecciones relacionadas al cuidar en salud, por microorganismos resistentes, y también investigar su relación con la mortalidad de los pacientes en un centro de terapia intensiva. Se trata de un estudio epidemiológico prospectivo realizado entre 2005 y 2008, envolviendo 2.300 pacientes. Se utilizó la estadística descriptiva y el análisis de regresión logístico bivariado y multivariado. En el análisis bivariado, la infección por microorganismos resistentes estuvo significativamente asociada a pacientes con infección comunitaria (p=0,03; OR=1,79) y a la colonización por microorganismo resistente (p<0,01; OR=14,22). En el análisis multivariado la severidad clínica C (p=0,03; OR=0,25) y la colonización por microorganismo resistente (p<0,01; OR=21,73) fueron significativas. En relación a las muertes, se observó como factor de riesgo: el tipo de paciente, la severidad clínica, y el uso de ventilación mecánica. La constatación de la relación entre los microorganismos resistentes y la muerte, coloca en evidencia la necesidad de monitorizar la adhesión a las medidas de control de la infección con el objetivo de mejorar la calidad de la asistencia y, sobre todo, la sobrevivencia de los pacientes críticos.

show abstract

Community-associated meticillin-resistant Staphylococcus aureus as a cause of hospital-acquired infections

Cited by 98 publications

References 37 publications

Epidemiology of antimicrobial resistance in bloodstream infections

Epidemiology of antimicrobial resistance in bloodstream infections

Methicillin-Resistant Staphylococcus aureus and the Eye: Current Concepts and Management Strategies

Bacterial Resistance and Mortality in an Intensive Care Unit

Contact Info

Product

Resources

About