Community-Acquired Acute Kidney Injury: A Nationwide Survey in China

Wang, Yafang; Wang, Jinwei; Su, Tao; Qu, Zhen; Yang, Li; Zhao, Ming‐Hui; Wang, Haiyan; Xing, Guolan; Liu, Z.; Wang, L.; Wang, F.; Wu, Yanhua; Huang, Dandan; Li, Suhua; Wang, S.; Xu, Gang; Ge, Shuwang; He, Qiang; Shen, Quanquan; Chen, J.; Zhang, P.; Chen, M.; Wu, Lei; Liu, X.; Pan, Miao; Zhu, Zaizhi; Zou, Xiting; Yang, Lin; Zhu, Ping; Lian, Xihua; Zhao, Jin; Ding, Feng; Zhou, Minjie; Li, Y.; Wang, Huamin; Hu, Weixian; Wang, Jianqin; Wang, Jing; Wang, R.; Liu, Bing; Mei, Changlin; Zhang, T.; Xu, Jixian; Han, Jianxin; Li, R.; Wen, Tao; Cao, Juan; Zhang, L.; Wang, Yan; Xu, Jinhua; Bao, Beihua; Liu, Bi‐Cheng; Chen, H.; Li, Shaomei; Zha, Yan; Luo, Qian; Chen, D.; Shen, Yulan; Liao, Yuanjiang; Zhang, Z.; Wang, Xinyue; Zhang, K.; Liu, L.; Mao, Peiju; Guo, Chunxiang; Li, J.; Wang, Z.; Bai, Shoujun; Shi, Shuangjie

doi:10.1053/j.ajkd.2016.10.034

Cited by 55 publications

(56 citation statements)

References 25 publications

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“…Worldwide, the proportion of community‐acquired AKI (CA‐AKI) cases has been reported to vary widely (30–84.3%) based on single‐centre studies. In China, CA‐AKI contributes to 54.4% of AKI, with a higher proportion in local hospitals than in tertiary hospitals (65.8% vs 50.5%), but the proportion does not vary among regions with different latitudes or economic status . The causes of CA‐AKI vary from north to south.…”

Section: Aki In Mainland Chinamentioning

confidence: 99%

“…As a general rule, in areas at the same latitudes, detected CA‐AKI rates were greater when GDP (Gross Domestic Product) per capita was higher; a higher GDP would most likely lead to increased rates of physician referral and hospital admission for patients with CA‐AKI. In regions with higher per capita GDP, more patients received timely diagnoses and the appropriate RRT …”

Section: Aki In Mainland Chinamentioning

confidence: 99%

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Perspectives on acute kidney injury strategy in China

Zhao

Yang

2018

Nephrology

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Acute kidney injury (AKI) has imposed a heavy disease burden in China, with substantial underdiagnosis and undertreatment. The incidence, cause and outcome of patients with AKI vary according to different geographic regions and economic development status; therefore, regional improvement strategies are needed. Defining the etiology of AKI is critical in making the proper therapeutic regimen, and a multidisciplinary cooperative AKI team is essential in order to establish the early diagnosis and proper management of patients with AKI.

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Section: Aki In Mainland Chinamentioning

confidence: 99%

Section: Aki In Mainland Chinamentioning

confidence: 99%

Perspectives on acute kidney injury strategy in China

Zhao

Yang

2018

Nephrology

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“…While numerous studies have focused on the epidemiology and clinical outcomes of patients who developed AKI during hospitalization—hospital‐acquired (HA)‐AKI—little is known about community‐acquired (CA)‐AKI (before hospitalization); nine studies have examined it . CA‐AKI was actually about two to four times more common than HA‐AKI.…”

Section: Epidemiology Of Akimentioning

confidence: 99%

Acute kidney injury: Epidemiology, outcomes, complications, and therapeutic strategies

Negi

Koreeda

Kobayashi

et al. 2018

Seminars in Dialysis

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Acute kidney injury (AKI) is one of the most common serious complications for all hospital admissions, with its incidence increasing among hospitalized patients, particularly those in the intensive care unit. Despite significant improvements in critical care and dialysis technology, AKI is associated with an increased risk of short- and long-term mortality, prolonged hospital stays, and dialysis dependence. These risks are particularly relevant for critically ill patients with AKI severe enough to require renal replacement therapy (RRT). No specific pharmacologic treatment has been established to treat AKI. Hence, the mainstay treatment for patients with AKI is RRT even though there are still several problematic issues regarding its use including RRT modality, dose, and timing. Recently, the impact of AKI on an increased risk of progression to chronic kidney disease (CKD) and end-stage renal disease requiring dialysis or transplantation is attracting increased attention.

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“…Another factor to consider is the high incidence of AKI in the hospital settings of areas with more resources, in contrast to community hospitals and rural areas, where AKI is often not detected [8,19,[22][23][24][25][26]. Nonetheless, AKI in this population is often preventable and reversible, affecting young, previously healthy individuals and might be secondary to tropical infectious diseases, animal venoms, the use of herbal medicine, complications of pregnancy including septic abortion, and infectious diarrhea (Table 1).…”

Section: Aki Meta-analysismentioning

confidence: 99%

“…Usage and distribution for commercial purposes as well as any distribution of modified material requires written permission. points were essential for the initiative: defining preventable death from AKI and promoting local recommendations for AKI care considering the health-care infrastructure and socioeconomic conditions [1,[16][17][18][19]. Based on previous studies, preventable deaths from AKI are known to occur as a result of 3 different situations [1]: (1) secondary to public health problems such as unclean water, diarrhea, and endemic infections; (2) delayed or lack of recognition, lack of access to laboratory studies, inadequate response, or iatrogenic factors resulting in additional insults to a failing kidney; and (3) lack of dialysis support to treat lifethreatening hyperkalemia, fluid overload, and acidosis [1].…”

Section: Introduction Of 0 By 25 Projectsmentioning

confidence: 99%

International Society of Nephrology 0 by 25 Project: Lessons Learned

et al. 2019

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Acute kidney injury (AKI) is a common disorder with a high risk of mortality and development of chronic kidney disease. With the validation of the recent classification systems, RIFLE in 2004 and KDIGO, in use today, our understanding of AKI has evolved. We now know that community-acquired AKI is also associated with an increased risk of worse outcomes. In addition, several epidemiological studies, including cohorts from low-income and low-middle income countries, have confirmed common risk factors for community-acquired AKI. In 2013, the International Society of Nephrology launched the 0 by 25 campaign with the goal that no patient should die from preventable or untreated AKI in low-resource areas by 2025 [Mehta et al.: Lancet 2015;385:2616–43]. The initial effort of the initiative was a meta-analysis of AKI epidemiology around the world. The second project of the 0 by 25 initiative, the Global AKI Snapshot (GSN) study, provided insights into the recognition, treatment, and outcomes of AKI worldwide [Mehta et al.: Lancet 2016;387:2017–25]. Following the GSN, a Pilot Project was designed to test whether education and a simple protocol-based approach can improve outcomes in patients at risk of community-acquired AKI in low-resource settings [Macedo: J Am Soc Nephrol 2017]. In this review, we will comment on the main findings and lessons learned from the 0 by 25 initiative.

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Community-Acquired Acute Kidney Injury: A Nationwide Survey in China

Cited by 55 publications

References 25 publications

Perspectives on acute kidney injury strategy in China

Perspectives on acute kidney injury strategy in China

Acute kidney injury: Epidemiology, outcomes, complications, and therapeutic strategies

International Society of Nephrology 0 by 25 Project: Lessons Learned

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