Common variable immunodeficiency with pernicious anemia, asthma, and reactions to gamma globulin; treatment with plasma

Ehtessabian, Reza; Cassidy, James T.; Thomas, M; Mathews, Kenneth P.; Tubergen, David G.

doi:10.1016/0091-6749(76)90140-8

Cited by 7 publications

(2 citation statements)

References 34 publications

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“…Immune globulins are also considered relatively free of immediate side effects, and the severe reactions to intravenously administered immune globulins [3] have received much more attention than those observed after intramuscular injections. Nevertheless, a considerable number of authors have reported adverse reactions to immune globulin given by the intramuscular route [21,[38][39][40]53,69,77,81,87,143,144,147,172,182,184]. The exact incidence of untoward reactions is difficult, if not impossible, to determine; figures reported have ranged from 0 [50] to 25% [21].…”

Section: Adverse Reactions To Immune Globulinsmentioning

confidence: 99%

Immune Globulins

Finlayson¹

1980

Semin Thromb Hemost

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Section: Adverse Reactions To Immune Globulinsmentioning

confidence: 99%

Immune Globulins

Finlayson¹

1980

Semin Thromb Hemost

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“…Various schemes to depict the interaction between insulin and glucagon with respect to blood plasma glucose levels can be found, mainly on the internet; although most of them are part of popular science internet sites or publications and the information they present is by large scientifically sound, significant information is not shown, such as the succession of the body's biochemical responses [7,8] or the role of a meal in raising blood glucose levels [9]. Hence, a single scheme that complements the glucose-fatty acid cycle and demonstrates the major shifts that occur in metabolism in the postprandial and in the fasting state, including the effects of the major hormones, in a concise and accurate way could not be found.…”

Section: Introductionmentioning

confidence: 99%

Meal–insulin cycle: A visual summary of the biochemical events between meals

Kalogiannis

2016

Biochem Molecular Bio Educ

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In the present article, a scheme that summarizes the biochemical events occurring in the human body after the consumption of a meal is proposed. The scheme illustrates the metabolic sequence as a series of counteracting components occupying opposite positions in a cycle, indicating their opposite actions or physiological states, such as meal versus energy consumption, increase versus decrease of blood glucose levels, and excretion of insulin versus excretion of glucagon. Furthermore, the cycle is complemented by a table indicating the acceleration or inhibition of selected metabolic pathways and actions. Since the cycle demonstrates the effects of a meal and of insulin on metabolism it was named "the meal-insulin cycle." Evaluation of the implementation in the classroom by postgraduate students of Nutrition showed that the proposed summarized visualization improved the understanding of the events between meals of all students, both holders of a Nutrition degree as well as graduates of another science division. Moreover, the representation as a perpetuating cycle throughout our lifespan was new to the students. The students recognized the graphical illustration as the most helpful feature. The proposed scheme may be used in teaching metabolism or biochemistry in a students' course or in a diabetes care course, it can be found on the internet, at the URL www.metpath.teithe.gr/meal_insulin_cycle and is linked to an interactive map of metabolic pathways. © 2016 by The International Union of Biochemistry and Molecular Biology, 45(3):279-284, 2017.

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Considerations for Use of Acupuncture as Supplemental Therapy for Patients with Allergic Asthma

Yang

Chen

Wang

et al. 2012

Clinic Rev Allerg Immunol

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This study examines the clinical and immunomodulatory effects of acupuncture in the treatment of patients with allergic asthma. The acupuncture points GV14, BL12, and BL13 were selected based on the theory of traditional Chinese medicine in treating asthma. Manual acupuncture was performed once every other day (three times per week) for 5 weeks. The needles were twisted approximately 360° evenly at the rate of 60 times/min for 20 s, manipulated every 10 min and withdrawn after 30 min. Concentrations of sIgA and total IgA in secretions were determined by the combination of sucrose density gradient ultracentrifugation and RIA. Levels of cortisol in the plasma were measured by RIA. Total IgE in the sera was examined by ELISA. Flow cytometry was used to detect the numbers of CD3+, CD4+, CD8+, and IL-2R + T lymphocytes in the peripheral blood. The absolute and differential numbers of eosinophils in peripheral blood were counted with eosin staining. The total efficacy of the acupuncture treatment in patients with allergic asthma at the end of one course of treatment was 85 %. After treatment, the concentrations of sIgA and total IgA in the saliva (P<0.01, P<0.02) and nasal secretions (P<0.02, P<0.02) were significantly decreased in patients with allergic asthma. The levels of total IgE in sera (P<0.001), the counts of IL-2R + T lymphocytes (P<0.001), and the absolute and differential numbers of eosinophils (P<0.01, P<0.01) in the peripheral blood were also significantly decreased. The numbers of CD3+, CD4+, and CD8+ T lymphocytes in the peripheral blood were significantly increased in the allergic asthmatics treated by acupuncture (P<0.001, P<0.01, and P<0.001, respectively). The concentration of cortisol in the plasma of asthmatic patients did not change significantly after the acupuncture treatment (P>0.05). Acupuncture has regulatory effects on mucosal and cellular immunity in patients with allergic asthma and may be an adjunctive therapy for allergic asthma.

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Common variable immunodeficiency with pernicious anemia, asthma, and reactions to gamma globulin; treatment with plasma

Cited by 7 publications

References 34 publications

Immune Globulins

Immune Globulins

Meal–insulin cycle: A visual summary of the biochemical events between meals

Considerations for Use of Acupuncture as Supplemental Therapy for Patients with Allergic Asthma

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