Common Craniofacial Anomalies: Conditions of Craniofacial Atrophy/Hypoplasia and Neoplasia

Abstract

The spectrum of craniofacial malformations includes conditions of congenital and acquired etiology. The conditions of craniofacial atrophy and hypoplasia may arise primarily or secondary to previous therapeutic interventions. The conditions of progressive hemifacial atrophy (Romberg disease) and radiation-induced hypoplasia will be reviewed on the basis of their etiology, pathogenesis, anatomy, and treatment. Approaches to the surgical management of these conditions will be discussed. The craniofacial neoplastic conditions of fibrous dysplasia, neurofibromatosis, and craniofacial tumors will also be reviewed and discussed.

Micro-well texture printed into PEG hydrogels using the FILM nanomanufacturing process affects the behavior of preadipocytes

“…These contour defects can be psychologically devastating to patients and, in many cases, physical impairments also result (e.g., loss of range of motion). Current reconstructive treatments consist of implanting or injecting synthetic materials or injecting autologous fat tissue (fat tissue removed from other parts of the patient's own body; Wang et al 2005;Hunt and Hobar 2003;Vaienti et al 2005;Asai et al 2006). These treatments are far from ideal.…”

Rombergʼs Disease Associated with Hornerʼs Syndrome: Contour Restoration by a Free Anterolateral Thigh Perforator Flap and Ancillary Procedures

“…The onset of the disease is slow and progressive and usually commences in the first or second decade of life, more often between the ages of 5 and 15 years. 1 It is more common in the female population, with a female-to-male ratio of 1.5 to 1. The atrophy is unilateral in 95 percent of cases.…”

Correction of Hemifacial Atrophy With Autologous Fat Transplantation

“…1 In general, the disease is characterized by a progressive hemifacial atrophy, followed by a stable "burned out" atrophic facial appearance. The main problem in patients with hemifacial atrophy is the lack of soft tissue in the atrophic area of the face, although the disease may also subsequently involve the facial muscles and skeleton.…”