Common Causes of Pleural Effusion in Referral Hospital in Isfahan, Iran 1997–1998

Golshan, Mohammad; Faghihi, Mehri; Ghanbarian, Khadijeh; Ghanei, Mustafa

doi:10.1177/021849230201000111

Cited by 10 publications

(11 citation statements)

References 17 publications

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“…Male to female ratio in pleural effusion reported by Sharma et al was 1.14:1 and a slight male predominance was reported by Golshan et al 19,20 In the present study, the male to female ratio for pleural effusion was 1.4:1 and for peritoneal fluid it was 1:1.5 which supports the previous studies.…”

Section: Discussionsupporting

confidence: 90%

The Role of Argyrophilic Nucleolar Organizer Region (AgNOR) Study in Cytological Evaluation of Fluids, Especially for Detection of Malignancy

Karki¹,

Jha²,

Sayami³

2012

Kathmandu Univ. Med. J.

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BackgroundSerous effusion smears reported as "suspicious for malignancy" pose problems in clinical management. Silver staining for argyrophilic nucleolar organizer regions (AgNOR) has proved useful in making a cytopathologic differential diagnosis between benign and malignant cells. Nucleolar organizer regions(NORs) are loops of DNA located in acrocentric chromosomes. These NORs are visualized by silver staining technique that recognizes these argyrophilia associated proteins which are increased in malignancy. ObjectiveThis study aimed to distinguish reactive mesothelial cells from malignant cells in serous effusions using these NORs. MethodsA total of 174 serous effusions received at the Department of Pathology, TUTH, during a period of one year were included in the study. Smears were studied by conventional Papanicolaou and Giemsa stains. AgNOR counts, variation in size and dispersion of AgNOR dots in smears were graded and compared in malignant and non-malignant effusions. ResultsMean AgNOR counts of 10.43±0.73 and 10.21±0.51 in malignant peritoneal and pleural effusions, respectively, were significantly (p<0.0001) greater as compared with counts of 2.12±0.54 and 2.11±0.54 in non-malignant effusions. The AgNORs were irregular in shape in malignant effusions whereas they were comparatively larger, single dots in benign effusions. AgNOR size and dispersion were of higher grade in significantly greater proportion of malignant as compared with non malignant effusions (p<0.0001). Of the cytologically suspicious samples, nine were in the malignant range and one was in the benign range. ConclusionAgNOR study appears to be clinically useful as an additional diagnostic tool for use in serous effusion when the cytologic diagnosis is difficult.

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Section: Discussionsupporting

confidence: 90%

The Role of Argyrophilic Nucleolar Organizer Region (AgNOR) Study in Cytological Evaluation of Fluids, Especially for Detection of Malignancy

Karki¹,

Jha²,

Sayami³

2012

Kathmandu Univ. Med. J.

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“…Cardiomegaly was seen in majority of the cases (93.3%) and was frequently (33%) associated with bilateral Pleural Effusion on the study of C X-rays. This was comparable with the study carried by M Golshan et al 24 who found CKD as a cause of pleural effusion in 6 of 106 patients with transudative pleural effusion in his study involving 213 patients with pleural effusion. This observation was also backed by another study conducted by Ray S et al 23 whose study had CKD, uremic pleural effusion accounted for 19% of the total pleural effusion cases studied by them.…”

Section: Electrocardiography (Ecg)supporting

confidence: 91%

Cardiac status in patients of chronic kidney disease: an assessment by non-invasive tools

Singal

Gupta

et al. 2016

Bangladesh J Med Sci

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Background: Chronic Renal Insufficiency is a major public health problem. Cardiovascular Disease is the leading cause of morbidity and mortality in patients at every stage of Chronic Kidney Disease. There is a 10-200 fold increased risk of cardiovascular disease in those with Chronic Kidney Disease compared to the age and sex matched with general population, depending on the stage of Chronic Kidney Disease. Objective: The objective of the study was to see correlation, if any, of cardiac status and stage of kidney disease. Materials and methods: The study was conducted at M. M. Institute of Medical Sciences and Research, Mullana, Ambala. Thirty patients of Chronic Kidney Disease were included in the study. Chronic Kidney Disease is defined as kidney damage lasting for more than 3 months characterised by structural or functional abnormalities of the kidney, with or without decreased Glomerular Filtration Rate (GFR), according to the K/DOQI Guidelines. Inclusion criteria were based on symptomatology and clinical history of features suggestive of Chronic Kidney Disease. Symptoms, Signs and history of the patients were used to filter out patients who did not fit in the criteria and selected patients on the basis of criteria were further evaluated and investigated. All patients were subjected to detailed history and clinical examination. Patients with age <20 years, with history of Diabetes Mellitus, Dyslipidemia, Intrinsic Diseases of Ventricles, Congenital Heart Disease and chronic smokers were excluded from the study. A standard 12 lead ECG was done in all cases. Echocardiography was done in ECHO lab of Cardiology unit in MMIMSR. Echocardiographic assessment was done by using Model vivid Colour Doppler Echocardiography machine of GE make. Apical four chamber view was employed to obtain the measurements of Left ventricular volume in diastole and systole, Ejection fraction; Left Ventricular Indices were assessed and then were used to calculate Left Ventricular Mass by using the cube formula proposed by Devereux. Patients included in the study were treated as per the standard treatment schedule. The data obtained was analysed with appropriate statistical analysis tools at the end of the study and conclusive evidence was derived. Results: In the present study the mean Left Ventricular Mass was 249.76 ± 69.35 gms with 73% study cases having Left Ventricular Mass more than the reference range, also Left Ventricular Mass showed a progressive rise with increase in S. Creatinine levels. In the present study, Left Ventricular dysfunction was seen in nearly half of the cases while approximately one-fourth cases (23%) also had Systolic Dysfunction. Pericardial Effusion was also observed in 10 % the study cases in the present study.Conclusion: Cardiac functions particularly Left Ventricular parameters. Left Ventricular free wall thickness and Left Ventricular Mass being common abnormality in CKD patients.Bangladesh Journal of Medical Science Vol.15(2) 2016 p.207-215

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“…Pleural effusion can be caused by a variety of intrathoracic and systemic diseases, 37,38 and it is necessary to evaluate the cause of the effusion. During follow‐up of established HF patients, the US‐PLE sign usually appeared in relation to worsening HF in the present study.…”

Section: Discussionmentioning

confidence: 99%

“…In two other patients, such a US‐PLE event was due to malignant effusion due to lung cancer and parapneumonic effusion due to bacterial pneumonia. Thus, the presence of the US‐PLE sign as a persistent or increased amount of effusion despite augmented treatment for HF in established HF patients should undergo thoracentesis to reveal the possible cause of effusion other than HF through the analysis of pleural fluid 37,38 …”

Section: Discussionmentioning

confidence: 99%

Ultrasound Pleural Effusion Sign as a Useful Marker for Identifying Heart Failure Worsening in Established Heart Failure Patients During Follow‐Up

Kataoka

2012

Congestive Heart Failure

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Clinical significance of UltraSound Pleural Effusion (US-PLE) and test characteristics of this sign for identifying worsening heart failure (HF) during follow-up of HF patients are unclear. Clinical records of 83 established HF patients were examined. The diagnosis of worsening HF was classified as "highly certain,""probable,""uncertain," or "no" based on the combination of the changes in symptoms/signs and B-type natriuretic peptide (BNP). Routine test included searching for the US-PLE sign. During a follow-up of 652±456 days, 1826 visits were evaluated. Among the 83 study patients, 78 had at least one of the following: worsening symptom(s), HF-related sign(s), and/or elevated BNP levels (≥3-fold increase) at one or more clinic visits. The US-PLE sign was present at 83 visits of 49 study patients. Its appearance was associated with the presence of HF-related symptom(s)/sign(s) and BNP elevation (odds ratio, 53-177, P<.0001 each). The test characteristics of the US-PLE sign for diagnosis of high possibility of worsening HF status fulfilling the "highly certain" or "probable" criteria were: sensitivity (76.6%), specificity (98.6%), positive predictive value (71.1%), and negative predictive value (99.0%). The US-PLE sign has high diagnostic accuracy for identifying worsening HF, including asymptomatic events, in HF patients during follow-up.

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Common Causes of Pleural Effusion in Referral Hospital in Isfahan, Iran 1997–1998

Cited by 10 publications

References 17 publications

The Role of Argyrophilic Nucleolar Organizer Region (AgNOR) Study in Cytological Evaluation of Fluids, Especially for Detection of Malignancy

The Role of Argyrophilic Nucleolar Organizer Region (AgNOR) Study in Cytological Evaluation of Fluids, Especially for Detection of Malignancy

Cardiac status in patients of chronic kidney disease: an assessment by non-invasive tools

Ultrasound Pleural Effusion Sign as a Useful Marker for Identifying Heart Failure Worsening in Established Heart Failure Patients During Follow‐Up

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