“…These are critical processes for improving the acquisition of new skills, learning, and memory, and therefore have important implications in clinical populations such as stroke (Bliss and Cooke, 2011 ; Zeiler and Krakauer, 2013 ). Presently, there is a focus on determining the specifics of aerobic exercise prescription to optimally prime the brain (Ploughman et al, 2005 , 2008 ; Singh et al, 2014 ; Robertson et al, 2015 ; Saucedo Marquez et al, 2015 ; Hwang et al, 2016 ; Charalambous et al, 2017 ; Gentil and Del Vecchio, 2017 ; Kelly et al, 2017 ; Morais et al, 2017 ; Nepveu et al, 2017 ; Neva et al, 2017 ). The benefits of aerobic exercise appear to be intensity dependent (Ploughman et al, 2007b ; Hasan et al, 2016 ; Kelly et al, 2017 ) and several studies have shown that delivering high-intensity aerobic exercise protocols is superior to low or moderate intensity exercise (Ferris et al, 2007 ; Rojas et al, 2014 ; Saucedo Marquez et al, 2015 ; Hussain et al, 2016 ; MacInnis and Gibala, 2016 ).…”