Comment to the article titled: “Autonomic nervous system function in women with anorexia nervosa” by Jenkins and coll

Luca, Antonina; Luca, Maria Luisa De

doi:10.1007/s10286-022-00887-w

Cited by 1 publication

(1 citation statement)

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“…However, in the latest publication by Jenkins et al, there were no significant differences in baroreceptor function compared to healthy controls. The only notable difference was a lower tilt mean slope between the weight-restored AN group and the healthy control group [53].…”

Section: Blood Pressure Variability and Baroreceptorsmentioning

confidence: 81%

The autonomic nervous system in anorexia nervosa — an implication for the fat tissue

Boryczko,

Skowron,

Kurnik-Łucka

et al. 2023

Folia Medica Cracoviensia

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Eating disorders are a heterogeneous group of diseases affecting mainly young people in devel-oped countries. Among them, anorexia nervosa (AN) is the one with the highest mortality, up to five times higher compared to healthy individuals. The etiology of this medical condition is complex and still un-certain. However, disturbances of the autonomic nervous system (ANS) and increased lipolysis resulting in a decrease of the adipose tissue volume are common findings among AN patients. Since ANS is directly connected to adipocyte tissue, thus significantly affecting the body’s metabolic homeostasis, we suspect that this relationship may be a potential pathophysiological underpinning for the development of AN. In this narrative review, we have analyzed scientific reports on ANS activity in AN considering different phases of the disease in humans as well as animal models. Due to the different effects of the disease itself on the ANS as well as specific variations within animal models, the common feature seems to be dysre-gulation of its function without the identification of one universal pattern. Nonetheless, higher norepi-nephrine concentrations have been reported in adipocyte tissue, suggesting local dominance of the sym-pathetic nervous system. Further studies should explore in depth the modulation of sympathetic in adipose tissue factor and help answer key questions that arise during this brief narrative review.

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Section: Blood Pressure Variability and Baroreceptorsmentioning

confidence: 81%