Combining Microfractures, Autologous Bone Graft, and Autologous Matrix-Induced Chondrogenesis for the Treatment of Juvenile Osteochondral Talar Lesions

D’Ambrosi, Riccardo; Maccario, Camilla; Ursino, Chiara; Serra, Nicola; Usuelli, Federico Giuseppe

doi:10.1177/1071100716687367

Cited by 26 publications

(16 citation statements)

References 40 publications

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“…Significant pain relief was reported in all studies involving ankle cartilage defects treated with AMIC, as VAS decreased from 2-9 preoperatively to 0-3 within 5 years postoperatively (Table 4). 12,13,31,40,50-52,55-58 AOFAS ankle and hindfoot score improved from 17-79 preoperatively to 79-86 within 5 years postoperatively (applied in 11 of the 12 studies). 12,13,40,50-52,55-57 MOCART scoring was reported in only 6 of 12 studies.…”

Section: Resultsmentioning

confidence: 99%

“…§ Of the 11 identified clinical articles about AMIC combined with other materials or surgical procedures, 4 articles were reports of single cases 14,40,55,57 and 7 were case series of a total of 335 patients. 13,16,20,46,50,52,58 Only 3 studies compared the outcomes of AMIC with microfracture: 1 study of the hip 21 and 2 studies of the knee. 1,54 Only 1 study of the hip compared the outcomes between AMIC and matrix-assisted ACI.…”

Section: Resultsmentioning

confidence: 99%

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Autologous Matrix-Induced Chondrogenesis: A Systematic Review of the Clinical Evidence

2017

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This systematic review reveals a paucity of high-quality, randomized controlled studies testing the AMIC technique versus established procedures such as microfracture or ACI. Evidence is insufficient to recommend joint-specific indications for AMIC. Additional nonbiased, high-powered, randomized controlled clinical trials will provide better clinical and structural long-term evidence, thus helping to define possible indications for this technique.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Autologous Matrix-Induced Chondrogenesis: A Systematic Review of the Clinical Evidence

2017

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“…Furthermore, recently calcaneal bone grafts are also utilized in autologous matrix-induced chondrogenesis technique for the treatment of osteochondral talar lesion. 15 However, their usefulness and safety in rheumatoid foot surgery has not yet been reported. In our limited experience, autologous bone grafting from the calcaneus was very useful and safe even in RA patients.…”

Section: Discussionmentioning

confidence: 99%

Use of autologous bone grafting from the calcaneus and interconnected porous hydroxyapatite ceramic for bone transplantation in rheumatoid foot surgery

Hirao

Ebina

Etani

et al. 2018

SAGE Open Medical Case Reports

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Cancellous bone grafts from the calcaneus have been used for the foot and ankle as well as iliac bone graft; however, there is a sparse report for calcaneal bone transplantation in the field of rheumatoid foot surgery. In this study, safety and usefulness of calcaneal bone grafts, and combination with interconnected porous hydroxyapatite ceramic, was evaluated in rheumatoid arthritis foot surgeries. Of six rheumatoid arthritis cases, three (talo-navicular joint fusion) used a calcaneal bone graft alone, and the remaining three cases (subtalar joint and talo-navicular joint fusion) used a combination of calcaneal bone graft and interconnected porous hydroxyapatite ceramic augmented with dense calcium hydroxyapatite for subtalar bony defect (1.5–2.0 cm) after the correction. Pre- and postoperative Japanese Society for Surgery of the Foot rheumatoid arthritis foot ankle scale scores were obtained for the clinical assessment. As radiographic assessment, tibio-calcaneal angle, calcaneal pitch, talo-1st metatarsal angle, and pronated foot index were also evaluated. After starting weight-bearing or walking, there was no pain and skin trouble at the fusion and harvesting sites. All cases achieved bony fusion within 6–10 weeks. Japanese Society for Surgery of the Foot rheumatoid arthritis foot ankle score was improved in all six cases. Furthermore, tibio-calcaneal angle, talo-1st metatarsal angle, and pronated foot index were also improved at latest follow-up in all cases. In conclusion, autologous bone grafting from the calcaneus was safe and convenient even in rheumatoid foot surgeries. For larger bony defects (1.5–2.0 cm), combination use with interconnected porous hydroxyapatite ceramic augmented with dense calcium hydroxyapatite was also useful.

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“… 9 A case series study on the use of AMIC ® with bone grafting for chondral talar lesions presented good clinical results after two years of follow-up. 10 …”

Section: Discussionmentioning

confidence: 99%

Osteochondritis dissecans of the trochlea: case report

Gracitelli

Rezende

Martimbianco

et al. 2018

Revista Brasileira de Ortopedia (English Edition)

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Combining Microfractures, Autologous Bone Graft, and Autologous Matrix-Induced Chondrogenesis for the Treatment of Juvenile Osteochondral Talar Lesions

Abstract: Level IV, retrospective case series.

Cited by 26 publications

References 40 publications

Autologous Matrix-Induced Chondrogenesis: A Systematic Review of the Clinical Evidence

Autologous Matrix-Induced Chondrogenesis: A Systematic Review of the Clinical Evidence

Use of autologous bone grafting from the calcaneus and interconnected porous hydroxyapatite ceramic for bone transplantation in rheumatoid foot surgery

Osteochondritis dissecans of the trochlea: case report

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