Combined use of laser correlation spectroscopy and ICP-AES, ICP-MS determination of macro- and trace elements in human biosubstrates for intoxication risk assessment

Karganov, M. Yu.; Skalny, Anatoly V.; Алчинова, И. Б.; Хлебникова, Н. Н.; Grabeklis, Andrei R.; Lakarova, E.V.; Eisazadeh, S.

doi:10.5414/tep28124

Cited by 13 publications

(12 citation statements)

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“…Exposure to ionizing radiation exhausts the pool of stem increases differentiated cell stress, and activated reparation and apoptosis processes. Laser correlation spectroscopy allows evaluation of changes in serum homeostasis [9]. In irradiated 101/Hf mice, an increase in the one particles into light scattering during week 3 and a shift of the second zone towards larger particles in comparison with the control were observed.…”

Section: Comparison Of Blood Cell Content In Three Mouse Strains Aftementioning

confidence: 99%

The Effects of Gamma-Irradiation in Sub-Lethal Doses in Mice with Different Radiosensitivity

Medvedeva¹

2015

AJLS

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Abstract:Reactions to gamma-irradiation in an acute dose of 750 R in C57BL/6, 101/Hf and С3H/Sn mice at different physiological levels were analyzed. In C3H/Sn and 101/Hf mice, light scattering spectrum was shifted towards small particles, while in C57BL/6 mice increased contribution of large particles was observed. In 3 weeks, a shift towards larger particles was recorded in all three mouse strains, but its degree varied. By week 6, the histograms approached the control. Histological study showed that the incidence of severe injuries in the liver increased by the end of the experiment in C57BL/6 mice (but not in other mouse strains). The same shifts were observed in the pancreas and an opposite tendency was seen in the spleen. Thus, C57BL/6 mice responded to irradiation later that C3H/Sn and 101/Hf mice, but demonstrated high adaptation capacity. C3H/Sn mice best of all recovered from the radiation crisis.

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Section: Comparison Of Blood Cell Content In Three Mouse Strains Aftementioning

confidence: 99%

The Effects of Gamma-Irradiation in Sub-Lethal Doses in Mice with Different Radiosensitivity

Medvedeva¹

2015

AJLS

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“…So, the presented data are good illustrations of the necessity of complex biophysical and biochemical investigation in life sciences, because biosphere is an assembly of bioelements and living organisms, existing under permanent regulatory influence of physic-chemical factors (Skalny, 2011). Biophysics is a vast cross-disciplinary subject encompassing the fields of biology, physics and computational biology etc in microbes, plants, animals and human being.…”

Section: Rat Spleen Genome Dna Stability In Experimental Model Of Folmentioning

confidence: 99%

“…More numerous sample and broader range of effective concentrations are required for deciphering of the real significance of the detected relationships (Karganov et al, 2011).…”

Section: The Content Of Chemical Elements In Biosubstrates Was Measurmentioning

confidence: 99%

“…Bioelements are the elemental functioning units of living matter, which are biologically active complexes of chemical elements as atoms, ions and nanoparticles with organic compounds of exogenous (primary) or biogenous (secondary) origin (Skalny, 2009(Skalny, , 2011. Evaluation of subfraction composition of samples provides information on percentage of biosubstrate constituents and yields integral characteristics reflecting the function of systems and their readiness to adequate protection of the body.…”

Section: Introductionmentioning

confidence: 99%

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Laser Correlation Spectroscopy: Nutritional, Ecological and Toxic Aspects

Karganov¹,

Алчинова²,

Arkhipova³

et al. 2012

Biophysics

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“…39.003.A N 5381, St. Petersburg). The method is based on changes in spectral characteristics of monochromatic coherent helium-neon laser radiation due to light scatter in disperse system (blood serum, urine, and other biological fluids) (Karganov et al, 2011). The degree of this scatter is proportional to particle speed, which depends on its hydrodynamic radius.…”

Section: Methodsmentioning

confidence: 99%