Combined Transvaginal B-Mode and Color Doppler Sonography for Differential Diagnosis of Ovarian Tumors: Results of a Multivariate Logistic Regression Analysis

A new computer-aided diagnostic tool for non-invasive characterisation of malignant ovarian masses: results of a multicentre validation study

“…Neither B-mode morphological scoring systems [17][18][19][20][21] nor Doppler quantitative analysis [22,23] was used to evaluate the ovaries. All study investigators performed a simple descriptive assessment of the presence or absence of arterial vessels, septa, unilocular or multilocular cysts within the mass, following the previously published guidelines [24][25][26][27][28] for ultrasound classification of ovaries. Based on that descriptive analysis alone, investigators were asked to classify each ovary seen as positive (malignant) or negative (benign) for malignancy.…”

Doppler Evaluation of the Ovary: Clinical Applications and Challenges

“…Blood flow data should be considered to indicate the angiogenic intensity of a tumor, rather than indicating malignancy itself. [10][11][12] It seems clear that initial attempts to classify ovarian tumors solely on the basis of their impedance to blood flow have been too simplistic. This problem has been partly solved by the introduction of other 'vascular parameters' such as blood vessel arrangement and location, shape of the pulsed Doppler waveform and appearance of an early diastolic notch, as well as assessment of blood flow velocities.…”

The Role of 3D Ultrasound and 3D Power Doppler Imaging in the Diagnosis and Evaluation of Ovarian Cancer: New Perspectives

“…Other authors, however, point out that the most important variable in predicting malignancy is the presence or absence of solid elements within the tumor, and find that the use of 3D transvaginal sonography does not significantly improve the 2D transvaginal sonographic morphologic assessment of complex adnexal masses, though it is useful for reinforcing initial diagnostic impressions. [19][20][21] Concerning power Doppler evaluation of complex adnexal masses, Cohen et al published a study over 71 women in which despite all malignancies were correctly identified by both 2D and 3D imaging, the specificity was significantly improved with the addition of 3D power Doppler.…”