“…This study showed that protected CAS is a feasible and safe procedure with a very low 2.2% 30-day neurological complication rate, which is comparable to other studies of unprotected carotid stenting and historical surgical controls. 16,18,21,37,44,45 However, cerebral protection cannot prevent all embolic events that may occur at all steps in the procedure. The balloon protection device is active against embolism only after the wire has crossed the lesion; this maneuver and even the initial positioning of the guide catheter in the CCA can release embolic material.…”