Combined magnetic resonance imaging of deep venous thrombosis and pulmonary arteries after a single injection of a blood pool contrast agent

Hansch, Andreas; Betge, Stefan; Poehlmann, Gunther; Neumann, Steffi; Baltzer, Pascal; Pfeil, Alexander; Waginger, Matthias; Boettcher, Joachim; Kaiser, Werner A.; Wolf, Günter; Mentzel, Hans‐Joachim

doi:10.1007/s00330-010-1918-0

Cited by 38 publications

(24 citation statements)

References 22 publications

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“…From a clinical perspective, our study is in line with a recent report from Pfeil et al, who observed patients with symptoms of PE and no evidence of PE on CT . Some studies suggested alternative imaging technique like MRI for the diagnosis of the PE . Although MRI has no IOV, CEUS is cheaper, is much faster, and can also be performed in patients with pacemaker or other contraindications for MRI.…”

Section: Discussionsupporting

confidence: 90%

Detection of peripheral embolic consolidations using contrast‐enhanced ultrasonography in patients with no evidence of pulmonary embolism on computed tomography: A pilot study

Trenker

Apitzsch²,

Pastor

et al. 2017

J of Clinical Ultrasound

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Despite the lack of definite confirmation of peripheral and central PE on CT, peripheral pleural consolidations with no or inhomogeneous enhancement on CEUS, in combination with the risk profile for a PE, are highly suggestive of EC. If there is still some doubt, histologic confirmation is important to confirm EC and exclude malignancy. Thus, CEUS may close a potential diagnostic gap of small peripheral PE on CT. © 2017 Wiley Periodicals, Inc. J Clin Ultrasound 45:575-579, 2017.

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Section: Discussionsupporting

confidence: 90%

Detection of peripheral embolic consolidations using contrast‐enhanced ultrasonography in patients with no evidence of pulmonary embolism on computed tomography: A pilot study

Trenker

Apitzsch²,

Pastor

et al. 2017

J of Clinical Ultrasound

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“…To determine the regional difference of mean PBF, PBV and MTT in the gravitational direction, all slices were divided into three groups as follows: ventral (slices 1-10), middle (slices [15][16][17][18][19][20][21][22][23][24][25] and dorsal (slices 30-40, Fig. 3b).…”

Section: Perfusion Quantification Using Contrast-enhanced Perfusion Mrimentioning

confidence: 99%

“…they rapidly diffuse into the parenchyma. The recently introduced blood pool MR contrast agent, gadofosveset [18,19], remains longer in the intravascular circulation with no parenchymal extravasate.…”

Section: Introductionmentioning

confidence: 99%

Quantitative evaluation of MR perfusion imaging using blood pool contrast agent in subjects without pulmonary diseases and in patients with pulmonary embolism

et al. 2012

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“…By Hoffer E. K. et al [18] MRV is effective and accurate, with a sensitivity and specificity for iliac and femoral DVT approaching 100 % compared with venography and a 92 % sensitivity in detecting isolated calf-vein thrombus. A variety of sequences can be utilized, including spin-echo, gradient-recalled echo, and gadolinium-enhanced images [21,22,23].…”

Section: Magnetic Resonance Venographymentioning

confidence: 99%

Modern Methods of Deep Vein Thrombosis Diagnosis: Literature Review

Zostautiene

Žvinienė

Kiudelis

2016

Medicinos Teorija Ir Praktika

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SANTRAUKAReikšminiai žodžiai: giliųjų venų trombozė, kompresinis ultragarsinis tyrimas, daugiasluoksnė kompiuterinė tomografija, magnetinis rezonansas, venografija. Venų tromboembolija (VTE) -tai dvi tarpusavyje susijusios patologijos: plaučių embolija (PE) ir giliųjų venų trombozė (GVT). Giliųjų venų trombozė išlieka svarbi sveikatos sistemos problema, kadangi yra susijusi su komplikacijomis, turinčiomis aukštą sergamumo ir mirtingumo rodiklį: ūminė ir lėtinė plaučių embolijos, plautinė hipertenzija ir potrombozinis sindromas. Paprastai GVT prasideda blauzdos venose, bet gali tęstis proksimaliau ir sąlygoti gyvybei pavojingą plaučių emboliją. Klinikinėje praktikoje labai svarbi šios ligos profilaktika ir gydymas, tad aktuali yra ankstyva ir tiksli diagnozė, įvertintant tikslią GVT vietą ir apimtį. Apibendrinus literatūros duomenis, straipsnyje apžvelgiami radiologinės diagnostikos metodai kojų giliųjų venų trombozei nustatyti, radiologinių tyrimų privalumai ir trūkumai. ABSTRACTKey words: deep vein thrombosis, compression ultrasound, multidetector computed tomography, magnetic resonance, venography. Venous thromboembolism consists of two related conditions: deep vein thrombosis and pulmonary embolism. One-third venous thromboembolism cases are manifested as pulmonary embolism and two-third present with deep vein thrombosis alone. Deep venous thrombosis remains an important health care problem as it is related with the complications having a high morbidity and mortality rate: acute and chronic pulmonary embolism, pulmonary hypertension and post-thrombotic syndrome. It is considered the third most common acute cardiovascular disease after ischemic heart disease and stroke and effects millions of people worldwide. Conventional venography was the gold standard in deep vein thrombosis diagnosis and the only imaging test for a long time in order to specify the suspected deep vein thrombosis in legs, pelvis or inferior vena cava [1,2]. Presently contrast x-ray venography is applied very seldom in conventional medical practice. Contrast x-ray venography is particularly helpful for assessing recurrent acute deep vein thrombosis in patients with a prior history of deep vein thrombosis in whom venous anatomy is often complex and difficult to evaluate using other methods [3] or when to remove an inferior vena cava filter. Conventional venography is presently replaced with non-invasive or less invasive radiological examination methods: the firstchoice method is ultrasound, but there are also other ones -computed tomography venography and magnetic resonance venography. Ultrasound is the imaging examination of choice for suspected lower extremity deep venous thrombosis. Ultrasound has high sensitivity (range, 93.2 %-95.0 %; pooled sensitivity, 94.2 %) and high specificity (range, 93.1 %-94.4 %; pooled specificity, 93.8 %) for diagnosing proximal (thigh) deep vein thrombosis and much lower sensitivity (range, 59.8 %-67.0 %; pooled sensitivity, 63.5 %) for diagnosing distal (calf ) and pelvic veins thrombosis. Compression ultra...

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Combined magnetic resonance imaging of deep venous thrombosis and pulmonary arteries after a single injection of a blood pool contrast agent

Abstract: This study shows the feasibility of a combined protocol for the MRI diagnosis of DVT and PE using gadofosveset trisodium. This procedure is not only more sensitive in detecting DVT compared to standard DUS, but is also able to detect PE in asymptomatic patients.

Cited by 38 publications

References 22 publications

Detection of peripheral embolic consolidations using contrast‐enhanced ultrasonography in patients with no evidence of pulmonary embolism on computed tomography: A pilot study

Detection of peripheral embolic consolidations using contrast‐enhanced ultrasonography in patients with no evidence of pulmonary embolism on computed tomography: A pilot study

Quantitative evaluation of MR perfusion imaging using blood pool contrast agent in subjects without pulmonary diseases and in patients with pulmonary embolism

Modern Methods of Deep Vein Thrombosis Diagnosis: Literature Review

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