SANTRAUKAReikšminiai žodžiai: giliųjų venų trombozė, kompresinis ultragarsinis tyrimas, daugiasluoksnė kompiuterinė tomografija, magnetinis rezonansas, venografija. Venų tromboembolija (VTE) -tai dvi tarpusavyje susijusios patologijos: plaučių embolija (PE) ir giliųjų venų trombozė (GVT). Giliųjų venų trombozė išlieka svarbi sveikatos sistemos problema, kadangi yra susijusi su komplikacijomis, turinčiomis aukštą sergamumo ir mirtingumo rodiklį: ūminė ir lėtinė plaučių embolijos, plautinė hipertenzija ir potrombozinis sindromas. Paprastai GVT prasideda blauzdos venose, bet gali tęstis proksimaliau ir sąlygoti gyvybei pavojingą plaučių emboliją. Klinikinėje praktikoje labai svarbi šios ligos profilaktika ir gydymas, tad aktuali yra ankstyva ir tiksli diagnozė, įvertintant tikslią GVT vietą ir apimtį. Apibendrinus literatūros duomenis, straipsnyje apžvelgiami radiologinės diagnostikos metodai kojų giliųjų venų trombozei nustatyti, radiologinių tyrimų privalumai ir trūkumai. ABSTRACTKey words: deep vein thrombosis, compression ultrasound, multidetector computed tomography, magnetic resonance, venography. Venous thromboembolism consists of two related conditions: deep vein thrombosis and pulmonary embolism. One-third venous thromboembolism cases are manifested as pulmonary embolism and two-third present with deep vein thrombosis alone. Deep venous thrombosis remains an important health care problem as it is related with the complications having a high morbidity and mortality rate: acute and chronic pulmonary embolism, pulmonary hypertension and post-thrombotic syndrome. It is considered the third most common acute cardiovascular disease after ischemic heart disease and stroke and effects millions of people worldwide. Conventional venography was the gold standard in deep vein thrombosis diagnosis and the only imaging test for a long time in order to specify the suspected deep vein thrombosis in legs, pelvis or inferior vena cava [1,2]. Presently contrast x-ray venography is applied very seldom in conventional medical practice. Contrast x-ray venography is particularly helpful for assessing recurrent acute deep vein thrombosis in patients with a prior history of deep vein thrombosis in whom venous anatomy is often complex and difficult to evaluate using other methods [3] or when to remove an inferior vena cava filter. Conventional venography is presently replaced with non-invasive or less invasive radiological examination methods: the firstchoice method is ultrasound, but there are also other ones -computed tomography venography and magnetic resonance venography. Ultrasound is the imaging examination of choice for suspected lower extremity deep venous thrombosis. Ultrasound has high sensitivity (range, 93.2 %-95.0 %; pooled sensitivity, 94.2 %) and high specificity (range, 93.1 %-94.4 %; pooled specificity, 93.8 %) for diagnosing proximal (thigh) deep vein thrombosis and much lower sensitivity (range, 59.8 %-67.0 %; pooled sensitivity, 63.5 %) for diagnosing distal (calf ) and pelvic veins thrombosis. Compression ultra...
Background: The aim of this study was to assess and recommend the optimal deep vein thrombosis (DVT) prophylaxis regimen during and after laparoscopic fundoplication according to the blood coagulation disorders and the rate of DVT in 2 patient groups, receiving different DVT prophylaxis regimens.
IntroductionThromboelastography (TEG) is a technique that measures coagulation processes and surveys the properties of a viscoelastic blood clot, from its formation to lysis.AimTo determine the possible hypercoagulability state and the effect of antithrombotic prophylaxis on thromboelastogram results and development of venous thrombosis during laparoscopic fundoplication.Material and methodsThe study was performed on 106 patients who were randomized into two groups. The first group received low-molecular-weight heparin (LMWH) 12 h before the operation, and 6 and 30 h after it. The second group received LMWH only 1 h before the laparoscopic fundoplication. The TEG profile was collected before LMWH injection, 1 h after the introduction of the laparoscope and 15 min after the surgery was completed.ResultsThere was no significant difference in thromboelastography R-time between the groups before low-molecular-weight heparin injection. In group I preoperative R-values significantly decreased 1 h after the introduction of the laparoscope, after the end of surgery and on the third postoperative day. K-time values decreased significantly on the third postoperative day compared with the results before low-molecular-weight heparin injection, and after the operation. In group II, preoperative R-values significantly decreased 1 h after the introduction of the laparoscope, and after surgery. K-time values did not change significantly during or after the laparoscopic operation.ConclusionsOur study results demonstrated that the hypercoagulation state (according to the TEG results) was observed during and after laparoscopic fundoplication in patients when LMWH was administered 12 h before the operation together with intraoperative intermittent pneumatic compression. The optimal anticoagulation was obtained when LMWH was administered 1 h before fundoplication.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.