Combination Treatment With Nefazodone and Cognitive-Behavioral Therapy for Relapse Prevention in Alcohol-Dependent Men

Wetzel, Hermann; Szegedi, Armin; Scheurich, Armin; Lörch, B.; Singer, Peter P.; Schläfke, Detlef; Sittinger, Helmut; Wobrock, Thomas; Müller, Matthias J.; Anghelescu, Ion; Hautzinger, Martin

doi:10.4088/jcp.v65n1017

Cited by 28 publications

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“…The current review also suggests larger effect sizes with shorter duration CBT interventions. However, of the 10 studies with greater than 20 sessions, 7 compared CBT with at least a support group or treatment as usual (Kadden et al, , 2001McKay et al, 1997;Rawson et al, 2002Rawson et al, , 2006Rosenblum et al, 2005;Wetzel et al, 2004). The current research therefore supports a benefi t from shorter CBT interventions, but whether this fi nding is also related to additional study characteristics, such as strength of comparison condition, requires further investigation.…”

Section: Discussionmentioning

confidence: 63%

Cognitive-Behavioral Treatment With Adult Alcohol and Illicit Drug Users: A Meta-Analysis of Randomized Controlled Trials

Magill

Ray

2009

J. Stud. Alcohol Drugs

603

347

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ABSTRACT. Objective:This meta-analysis examined 53 controlled trials of cognitive-behavioral treatment (CBT) for adults diagnosed with alcohol-or illicit-drug-use disorders. The aims were to provide an overall picture of CBT treatment effi cacy and to identify client or treatment factors predictive of CBT effect magnitude. Method: The inverse variance weighted effect size (Hedges' g) was calculated for each study and pooled using fi xed and random effects methods. Potential study-level moderators were assessed in subgroup analyses by primary drug, type of CBT, and type of comparison condition. In addition, seven client and treatment variables were examined in meta-regression analyses. Results: Across studies, CBT produced a small but statistically signifi cant treatment effect (g = 0.154, p < .005). The pooled effect was somewhat lower at 6-9 months (g = 0.115, p < .005) and continued to diminish at 12-month follow-up (g = 0.096, p < .05). The effect of CBT was largest in marijuana studies (g = 0.513, p < .005) and in studies with a no-treatment control as the comparison condition (g = 0.796, p < .005). Metaregression analyses indicated that the percentage of female participants was positively associated and the number of treatment sessions was negatively associated with effect size. Conclusions: The fi ndings demonstrate the utility of CBT across a large and diverse sample of studies and under rigorous conditions for establishing effi cacy. CBT effects were strongest with marijuana users, when CBT was compared with no treatment, and may be larger with women than with men and when delivered in a brief format. (J. Stud. Alcohol Drugs 70: 516-527, 2009) C OGNITIVE-BEHAVIORAL TREATMENT (CBT) models are among the most extensively evaluated interventions for alcohol-or illicit-drug-use disorders. Based primarily on Marlatt and Gordon's (1985; Marlatt and Donovan, 2005) model of relapse prevention, these treatments target cognitive, affective, and situational triggers for substance use and provide skills training specifi c to coping alternatives. CBT treatment for alcohol or illicit drug use often includes the following strategies: (1) identifying intrapersonal and interpersonal triggers for relapse, (2) coping-skills training, (3) drug-refusal skills training, (4) functional analysis of substance use, and (5) increasing nonuse-related activities. These models have been manualized (e.g., Kadden et al., 1992;Monti et al., 1989) and adapted for implementation in a variety of clinical capacities. Further, CBT interventions have been tested in Stage III research to examine their utility in the "real-world" context, possible adaptations, and costeffectiveness (National Institute on Drug Abuse, 1992; cited from Carroll and Onkin, 2005). As argued by Carroll and Rounsaville (2007), the addictions fi eld would benefi t from greater and continued attention devoted to the dissemination of research-based substance-use treatments. Review data to guide such efforts, however, are needed.CBT interventions for substance-use disorde...

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Section: Discussionmentioning

confidence: 63%

Cognitive-Behavioral Treatment With Adult Alcohol and Illicit Drug Users: A Meta-Analysis of Randomized Controlled Trials

Magill

Ray

2009

J. Stud. Alcohol Drugs

603

347

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“…For instance, using the definition of any drinking, Wetzel et al (2004) reported a relapse rate of 48% three months after treatment and 77% after 12 months. But they also measured relapse using a threshold of 60g of alcohol; with this definition the relapse rate was very similar to that observed with any drinking (46% and 76%, respectively).…”

Section: Resultsmentioning

confidence: 99%

“…But they also measured relapse using a threshold of 60g of alcohol; with this definition the relapse rate was very similar to that observed with any drinking (46% and 76%, respectively). This second measure allows the clarification that, at least for the study of Wetzel et al (2004), the high relapse rate can be related to the way heavy drinking is classified by any drinking measure.…”

Section: Resultsmentioning

confidence: 99%

“…The results of Wetzel et al (2004) shows that the registration of different outcomes allows a better understanding of relapse processes. According to Baer (2002), one indicator used to identify problematic drinking is the amount of alcohol consumed per episode.…”

Section: Discussionmentioning

confidence: 99%

“…Since definitions of the relapse are associated with different results (Maisto et al, 2003), the strategies and actions of health professional can more effectively improve treatment if they consider a better description of the entire drinking pattern (Wetzel et al, 2004).…”

Section: Discussionmentioning

confidence: 99%

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The Recovery from Alcohol Consumption: Analysis of the Construct of Relapse

Reyes-Huerta

Vacio

Pedroza

et al. 2018

Int. j. psychol. res.

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Objective: A systematic review was conducted to identify definitions that facilitated the study of relapse as both behavioral pattern and process. Methods: The review was conducted following the PRISMA-P guidelines. Articles that met the following inclusion criteria were considered: (a) published in peerreviewed journals, (b) provided an explicit operational definition of relapse, (c) assessed relapse during or after a specific psychological or self-care group intervention, (d) focused on alcohol consumption, and (e) were published between 2000 and September 2016. Results: "Any drinking" was the most frequent outcome used to identify relapse, although other discrete outcomes were also considered. Nevertheless, none of the definitions operationalize the notion of the return to a problematic drinking pattern and/or the process of relapse. Conclusion: Problems related to any drinking definition are discussed and we propose the use of a composed index to study relapse. ResumenObjetivo: Se realizó una revisión sistemática para identificar definiciones que permitieran el estudio de la recaída como un patrón y proceso conductual. Método: La revisión fue realizada siguiendo los lineamientos de la guía PRISMA-P. Los artículos que cumplían con los siguientes criterios fueron revisados: (1) publicados en revistas con revisión por pares, (b) definían explícitamente la recaída, (c) se evaluó la recaída después o durante un tratamiento psicológico o participación en un grupo de autoayuda, (d) la intervención se enfocaba en el consumo de alcohol, (d) publicados entre el año 2000 y septiembre de 2016. Resultados: Cualquier consumo fue el resultado más frecuentemente usado para definir la recaída, aunque otros resultados discretos también se consideraron. No obstante, ninguna de las definiciones operacionales reflejó la noción del regreso a un patrón de consumo problemático y/o el proceso a la recaída. Conclusiones: Problemas relacionados a la definición de cualquier consumo son discutidos y se propone un índice compuesto para estudiar la recaída.

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Combined Pharmacotherapy and Cognitive Behavioral Therapy for Adults With Alcohol or Substance Use Disorders

et al. 2020

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IMPORTANCE Substance use disorders (SUDs) represent a pressing public health concern. Combined behavioral and pharmacological interventions are considered best practices for addiction. Cognitive behavioral therapy (CBT) is a first-line intervention, yet the superiority of CBT compared with other behavioral treatments when combined with pharmacotherapy remains unclear. An understanding of the effects of combined CBT and pharmacotherapy will inform best-practice guidelines for treatment of SUD. OBJECTIVE To conduct a meta-analysis of the published literature on combined CBT and pharmacotherapy for adult alcohol use disorder (AUD) or other SUDs.

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Combination Treatment With Nefazodone and Cognitive-Behavioral Therapy for Relapse Prevention in Alcohol-Dependent Men

Cited by 28 publications

References 0 publications

Cognitive-Behavioral Treatment With Adult Alcohol and Illicit Drug Users: A Meta-Analysis of Randomized Controlled Trials

Cognitive-Behavioral Treatment With Adult Alcohol and Illicit Drug Users: A Meta-Analysis of Randomized Controlled Trials

The Recovery from Alcohol Consumption: Analysis of the Construct of Relapse

Combined Pharmacotherapy and Cognitive Behavioral Therapy for Adults With Alcohol or Substance Use Disorders

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