This paper studies the 2-distance chromatic number of some graph product. A coloring of [Formula: see text] is 2-distance if any two vertices at distance at most two from each other get different colors. The minimum number of colors in the 2-distance coloring of [Formula: see text] is the 2-distance chromatic number and denoted by [Formula: see text]. In this paper, we obtain some upper and lower bounds for the 2-distance chromatic number of the rooted product, generalized rooted product, hierarchical product and we determine exact value for the 2-distance chromatic number of the lexicographic product.