“…So far, many strategies have been developed for Cys and Cu 2+ detection, such as high-performance liquid chromatography (HPLC), , capillary electrophoresis, , electrochemistry, , gas chromatography, atomic emission/absorption spectrometry (AES/AAS), , surface plasmon resonance (SPR), colorimetric method, , and fluorometric method. − However, most of these methods suffer from expensive instruments and sophisticated operation; moreover, these methods detect Cys and Cu 2+ separately, thus needing different technologies and instruments, making it more complicated and time-consuming. In fact, there lies a strong interaction between Cys and Cu 2+ , , which makes it rational to build a sensing platform for their simultaneous detection in the same process, with the aim to shorten the detection time and simplify the measurement process.…”