Colorectal carcinoma in children

Karnak, İbrahìm; Çiftçi, Arbay Ö.; Şenocak, Mehmet Emìn; Büyükpamukçu, Nebìl

doi:10.1016/s0022-3468(99)90112-4

Cited by 92 publications

(94 citation statements)

References 16 publications

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“…Postoperative histological examination is considered the gold standard for diagnosis. Colorectal carcinoma in children may occur at any age, however, the majority of cases are identified in older children; 70-95% of cases occur in children >10 years of age (2,(4)(5)(6). The present study reports the case of colorectal carcinoma, diagnosed as signet-ring cell carcinoma, in a 9-year-old boy.…”

Section: Introductionmentioning

confidence: 75%

Signet-ring cell carcinoma of the colon: A case report of a 9-year-old boy

et al. 2015

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Abstract. Colorectal carcinomas are common in adults; however, they rarely occur in children. The present study reported the case of a colorectal carcinoma diagnosed as signet-ring cell carcinoma in a 9-year-old boy. The patient presented with acute intestinal obstruction symptoms, which persisted following 3 days of conservative treatment. The diagnosis was determined by emergency laparotomy and a mass was identified in the transverse colon proximal to the splenic flexure. Histological examination of the mass revealed signet-ring cell carcinoma. In addition, the present study aimed to discuss the diagnostic establishment and treatment of this rare disease in children. Due to the high mortality rate caused by delays in accurate diagnoses, signet-ring cell carcinoma in children promotes a specific diagnostic and surgical challenge.

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Section: Introductionmentioning

confidence: 75%

Signet-ring cell carcinoma of the colon: A case report of a 9-year-old boy

et al. 2015

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“…El cuadro clínico de presentación puede incluir anemia, dolor abdominal, sangrado digestivo bajo (proctorragia), pérdida de peso y cambios en los hábitos evacuatorios. [2][3][4] Anatómicamente, puede presentarse con igual frecuencia tanto en el colon derecho como izquierdo, con tendencia al crecimiento exofítico e invasión de la muscularis mucosae. Los ganglios linfáticos regionales, el hígado, los pulmones y los …”

Section: Discussionunclassified

“…[1][2][3][4] El tratamiento oncológico dependerá del estadio al momento del diagnóstico y requerirá, en general, la remoción del tumor junto con el pedículo vascular que lo irriga y los ganglios linfáticos regionales en un bloque. En algunos casos, además, será necesario el tratamiento quimioterápico neoadyuvante.…”

Section: Colorectal Adenocarcinoma In a 5 Year Old Girlunclassified

“…[11][12] Existen casos de presentación familiar, como la poliposis adenomatosa familiar y el síndrome de Lynch, aunque los de presentación "esporádica" son más frecuentes y con mejor pronóstico. 3 El tratamiento se basa en la resección quirúrgica con un margen mínimo de 5 cm de intestino sano tanto en sentido proximal como distal, junto con los ganglios regionales potencialmente involucrados. En los estadios más avanzados (TNM III y IV), se agrega quimioterapia adyuvante posterior.…”

Section: Figura 3 Resonancia Magnética Por Imágenes De Pelvis De Altunclassified

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Adenocarcinoma colorrectal en una niña de 5 años de edad

et al. 2015

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Arch Argent Pediatr 2015;113(6):e333-e335 / e333Presentación de casos clínicos RESUMEN El adenocarcinoma colorrectal es excepcional en niños, por lo que, generalmente, se lo diagnostica en estadios avanzados, con mal pronóstico. Presentamos el caso de una niña de 5 años de edad con proctorragia recurrente de 2 meses de evolución, sin alteraciones en los análisis de laboratorio, en quien se confirmó la existencia de un adenocarcinoma colorrectal por medio de una colonoscopía. La estatificación demostró un compromiso local sin enfermedad o metástasis a distancia. La paciente se trató con resección laparoscópica y quimioterapia adyuvante, y permaneció libre de enfermedad a 21 meses de seguimiento. Palabras clave: adenocarcinoma, neoplasias colorrectales, colonoscopía, hemotoquecia. ABSTRACTColorectal adenocarcinoma is exceptional in children, generally diagnosed in advanced stages, with worse prognosis. We report the case of a 5 year old girl with isolated hematochezia lasting two months without other findings, in whom a colorectal adenocarcinoma was confirmed by colonoscopy. Staging revealed localized disease, extending to perisigmoid fat and a few adjacent ganglia. She was treated by laparoscopic resection and adjuvant chemotherapy, being free of disease at 21 moths of follow-up.

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“…This distinct feature has already been documented in the old literature (Scholefield 1946;Hoerner 1958). Several cases of liver metastases in pediatric colorectal carcinoma have been reported (Ko et al 1995;Karnak et al 1999;Ameh and Nmadu 2000;Kam et al 2004;Hill et al 2007;Pandey et al 2008). Due to the small number of cases observed in children, it is currently not known whether the propensity to metastasize to the liver is similar to or different from CRCs of the adult age group, but CRC in young individuals is rapidly progressive, with a high rate of recurrence, both local and remote.…”

Section: Liver Metastases In Pediatric Colorectal Carcinomamentioning

confidence: 99%

Metastatic Liver Disease: Colorectal Carcinomas

Zimmermann

2016

Tumors and Tumor-Like Lesions of the Hepatobiliary Tract

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Colorectal carcinoma in children

Cited by 92 publications

References 16 publications

Signet-ring cell carcinoma of the colon: A case report of a 9-year-old boy

Signet-ring cell carcinoma of the colon: A case report of a 9-year-old boy

Adenocarcinoma colorrectal en una niña de 5 años de edad

Metastatic Liver Disease: Colorectal Carcinomas

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