Colorectal cancers in United Arab Emirates nationals: The Sheik Khalifa Medical Center's experience.

Abstract

442 Background: Previous reports suggested that colorectal cancers (CRC) appear at younger age in the United Arabs Emirates (UAE). However, these reports included nationals and expatriates in their analysis with heterogeneous population leading to biased analysis. our objective was to determine age and stage of disease in newly diagnosed UEA nationals with CRC treated at one major referral hospital in Abu Dhabi (SKMC) Methods: Charts of all patients diagnosed and/ or treated for CRC at SKMC between January 2000 and May 2011 were reviewed. Ultimately, only UEA nationals with diagnosis of adenocarcinoma of the colon and rectum were retained for further analysis. Results: Two hundreds six patients were diagnosed at SKMC as having colon or rectal carcinomas. Ninety two were expatriates and in 10 out of 113 nationals, the final diagnosis was squamous or adenosquamous carcinoma leaving 103 patients forming the population of this study. Median age was 57(10-100 years), with 59 men. The patient’s condition necessitated emergency operation in 38 and 15 either refused or were unfit for treatment mainly because of very advanced disease or severe co morbidity. The tumor location was: sigmoid: 46%, rectum: 33:, right colon :17% and 4% for descending and transverse colon. The stage of the disease was I; 4 pts, II: 16 pts, III 25 pts, IV in 49 pts and undetermined in 7. Resection was curative for 46 pts, palliative in 45, unknown in 10 and 2 refused surgery. Fifty one patients had their treatment essentially at SKMC and the others were treated both at SKMC and abroad. Average follow-up was 2 years and at last FU 39 were confirmed deceased, 29 were alive and the outcome in the remaining was unknown. Conclusions: UAE nationals with CRC presenting to our facility have relatively young age but presented with stage IV disease in half of the cases. Screening program for this population is warranted. Because a substantial number of patients had had their treatment abroad, rigorous follow-up and cancer outcome assessment was unreliable.

Colorectal Cancer in Saudi Arabia: The Way Forward

“…(Arnold et al, 2019). The percentage of patients presenting with regional and/ or distant metastasis is high (Alsanea et al, 2015;Dehni et al,2012;Kumar et al, 2015). Notably, recent advances in early detection screenings and treatment options have reduced CRC mortality in Europe and North America.…”

Colorectal Cancer screening in ambulatory healthcare service clinics in Abu Dhabi, United Arab Emirates in 2015–2016

“…Eleven cases of CRC were diagnosed: 3 in men and 8 in women, with a mean age of 61.09 ± 11.2 years (range, 40–74 years). In Sheikh Khalifa Medical City (SKMC), Abu Dhabi, 103 Emirati nationals (57.9% men) were diagnosed with colorectal adenocarcinomas between 2000 and 2011; the mean patient age was 57 years [ 21 ]. Men had a higher incidence of CRC in our study, similar to the HAAD data that showed that men are diagnosed with CRC more often [ 9 ].…”